Navigation Links
Study finds drug may cut down involuntary movements

The medication tetrabenazine cut down involuntary movement in patients with Huntington's disease on average by about 25 percent, with many patients experiencing a greater improvement, according to a study in the February 14 issue of the journal Neurology.

Overall, patients who received the medication were six times as likely to be considered by their doctors to have improved considerably, compared to participants who received a placebo.

Dr. Kathleen M. Shannon, neurologist and Huntington's disease specialist at the Huntington's Disease Society of America Center of Excellence at Rush University Medical Center, led the Rush study. Rush was one of 16 sites to participate in the randomized, controlled study which involved 84 patients.

Tetrabenazin is available in Europe and Canada ?but not the United States, but is currently being reviewed by the U.S. Food and Drug Administration. If approved, the medication would be the first authorized by the agency expressly for the treatment of Huntington's disease, which affects about 30,000 people in the United States.

"Huntington's disease is an inherited brain disorder that causes patients to experience uncontrollable jerky movements (chorea), as well as changes in personality, behavior, thinking and memory. There are no FDA-approved treatments for the chorea. Anti-psychotic drugs like haloperidol (Haldol) are commonly used to suppress chorea, but they cause many different side effects. This study shows that tetrabenazine can decrease chorea, and the drug is well-tolerated by most research subjects," said Shannon.

Tetrabenazine was originally developed in the 1950s to treat psychosis, but was quickly pushed aside by more effective medications. But doctors in the United Kingdom found it to be effective to treat the excessive involuntary movements of Huntington's, and it is approved for use in several nations. In the United States, tetrabenazine is designated as an "orphan drug" by the FD
'"/>

Source:Rush University Medical Center


Page: 1 2 3

Related biology news :

1. Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
2. Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs
3. UCLA Study Shows One-Third of Drug Ads in Medical Journals Do Not Contain References Supporting Medical Claims
4. Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
5. Study Links Ebola Outbreaks To Animal Carcasses
6. Breakthrough Microarray-based Technology for the Study of Cancer
7. NYU Study Reveals How Brains Immune System Fights Viral Encephalitis
8. Study finds more than one-third of human genome regulated by RNA
9. Leukemia Drug Breakthrough Study In New England Journal Of Medicine
10. Study identifies predictors of HIV drug resistance in patients beginning triple therapy
11. New Study from Affymetrix Laboratories Points to Changing View of How Genome Works
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Study finds drug may cut down involuntary movements

(Date:7/21/2014)... species, investigators have found that migration routes are under ... which is published in Ecology Letters , was ... of a bird and allow its long distance movement ... exhibited increased variability in their migratory routes: some used ... the same routes as one parental group on fall ...
(Date:7/21/2014)... for the evolution of life are now being developed ... an evolving system of species. Specifically, a recent model ... Finland in Joensuu accounts for species interactions with various ... an improvement on previous, simpler models, which apply random ... EPJ E demonstrate that the resulting replicator ecosystems ...
(Date:7/21/2014)... Women,s Hospital (BWH) have developed a scalable, next-generation platelet ... The work is a major biomedical advancement that will ... is published July 21, 2014 in Blood . ... of functional human platelets with virtually no disease transmission ... that may allow us meet the growing need for ...
Breaking Biology News(10 mins):Refined biological evolution model 2Scientists successfully generate human platelets using next-generation bioreactor 2
... Envisat and the Italian Space Agency,s COSMO-SkyMed, scientists have ... the 6.3 earthquake that shook the medieval town of ... Scientists from Italy,s Istituto per il Rilevamento Elettromagnetico dell, ... Vulcanologia (INGV) are studying Synthetic Aperture Radar (SAR) data ...
... into how the deadly Hendra virus spreads promises to ... the future. CSIRO Livestock Industries, scientists working at ... have made a major breakthrough in better understanding how ... humans. Funded by the Australian Biosecurity ...
... BioMed Central,s 3rd Annual Research Awards were announced at ... The event was attended by shortlisted authors, eminent researchers ... journalists. The Research Awards, now in their ... made universally accessible by open access publication. The Awards ...
Cached Biology News:Satellites show how Earth moved during Italy quake 2Minimizing the spread of deadly Hendra virus 2Open access research celebrated 2
(Date:7/22/2014)... Quorum Review IRB, the industry leader in central ... called Quick Step™ . The offering went live on ... industry’s need for seamless study start-up with a large volume ... planning 50 or more North American investigator sites, as well ... count of 80 or more. Qualifying studies may also enroll ...
(Date:7/22/2014)... Angeles, CA (PRWEB) July 22, 2014 ... test solutions with the debut of its fluorescent ... of Clinical Chemistry (AACC) meeting in Chicago, July ... or bench top versions, the HRDR-300 is a ... pending technology to analyze fluorescent lateral flow immunoassays ...
(Date:7/22/2014)... Lawrence, KS (PRWEB) July 22, 2014 ... as attention-deficit hyperactivity disorder (ADHD) is diagnosed, selecting medication ... trial and error. Analyzing brain patterns by using electroencephalography ... best result and thus lower the risk of adverse ... Electroencephalography Phenotypes and Biomarkers” in the current issue ...
(Date:7/22/2014)... SC (PRWEB) July 22, 2014 Dr. ... of those who have recognized that the greatest health ... and far too often needlessly deadly while trying to ... multitude of quasi-experts seeking to transform an enormous system ... , Dr. Williams, in his continuing series of Open ...
Breaking Biology Technology:Quorum Review IRB Launches New Quick Step™ Service for Large Clinical Trials 2Quorum Review IRB Launches New Quick Step™ Service for Large Clinical Trials 3Holomic to Debut HRDR-300 Fluorescent Immunoassay Reader at the AACC 2014 2Analyzing Brain Patterns with EEG Can Help Predict Effective Use of Medication 2Analyzing Brain Patterns with EEG Can Help Predict Effective Use of Medication 3Dr. Ira Williams Asks What’s Wrong With Jonathan Bush’s Book, Where Does It Hurt? 2
... N.J., March 18 Medarex, Inc. (Nasdaq: MEDX ... the Needham & Company Cancer Therapeutics: Today & Tomorrow Conference ... The event will be webcast live and will be available ... www.medarex.com . An archived edition of the presentation will ...
... StartUpHire launched today as the job search engine dedicated ... backed companies. These are some of the most ... been difficult to identify. The StartUpHire website, ... be filtered by industry, geography, functional area, investor, and ...
... XTL Biopharmaceuticals Ltd. (Nasdaq: XTLB ; TASE: ... ("EGMs") held earlier today.All of the resolutions at the ... of Mark Allouche, Dafna Cohen, Yaron Diament, David Grossman, ... appointed Chairman. Dafna Cohen and Yaron Diament were ...
Cached Biology Technology:StartUpHire Launches Comprehensive Search Engine for Jobs at Venture-Backed Companies 2StartUpHire Launches Comprehensive Search Engine for Jobs at Venture-Backed Companies 3Extraordinary General Meetings Statement -- XTL Also Announces Board and Management Changes 2
Human sVCAM-1/CD106 ELI-PAIR Kit...
GLP-1 (HYB 147-12)...
... Custom Synthesis Service provides you ... to knockdown any gene. We ... base pairs with terminal dT ... other lengths of your choice. ...
EDG-1 Western blot control Source: Cell Lysate Application: Western Blotting Control...
Biology Products: