Navigation Links
Studies on human genome variation provide insight into disease

The International HapMap Project was initiated with the primary goal of facilitating medical studies and understanding the genomic basis for human diseases. To coordinate with the journal Nature's publication describing the HapMap, the journal Genome Research is announcing a special issue entitled "Human Genome Variation," which is entirely devoted to studies using these data to provide insight into human biology and disease.

Predicting pregnancy success

Successful human reproduction and the maintenance of early pregnancy are dependent on a cluster of genes on chromosome 19 called the Luteinizing Hormone/Chorionic Gonadotropin Beta (LHB/CGB). During primate evolution, this cluster actively underwent numerous gene duplications and structural rearrangements, allowing the associated genes to acquire new biological functions.

In this month's issue of Genome Research, Dr. Maris Laan and her colleagues report their analysis of the LHB/CGB cluster in three human populations: European Estonians, African Mandenka, and Chinese Han. They demonstrate how gene conversion was critical for shaping the genetic diversity of this region in humans.

"This study paves the way for examining an individual's potential reproductive success based on sequence variants of the LHB/CGB genes," explains Laan. "We may be able to determine whether an individual is particularly susceptible to spontaneous abortions or reduced gonadal function, for example."

Contact:
Maris Laan, Ph.D.
Research Professor, University of Tartu, Estonia
Phone: +372-53495258
E-mail: maris@ebc.ee

X-ing out hereditary prostate cancer

According to the Prostate Cancer Foundation, one of every six American men develops prostate cancer, making it the most common form of non-skin cancer. Growing evidence suggests that there is a signific
'"/>

Source:Cold Spring Harbor Laboratory


Page: 1 2 3 4

Related biology news :

1. Studies reveal methods viruses use to sidestep immune system
2. Studies reveal how plague disables immune system, and how to exploit the process to make a vaccine
3. Studies clarify risk factors for mother-to-child transmission of hepatitis C virus
4. Studies suggest new brain protein may help in treating schizophrenia, insomnia and anxiety
5. Studies find general mechanism of cellular aging
6. Studies look at how genes affect antipsychotic drug response
7. Studies yield insight into the numerical brain
8. Studies force new view on biology of flavonoids
9. Novel technology detects human DNA mutations
10. Current human embryonic stem cell lines contaminated UCSD/Salk team finds
11. UWs Rosetta software to unlock secrets of many human proteins
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Studies human genome variation provide insight into disease

(Date:6/17/2015)... , June 17, 2015  Synaptics Inc. ... interface solutions, today announced that Xiaomi, one of ... Synaptics ® ClearPad ® family of ... driver integrated circuits (DDICs) for its latest smartphones, ... leveraging ClearPad for full in-cell display solutions and ...
(Date:6/16/2015)... Fingerprint Cards has received an order of 375 ... from one of its module partners in Asia ... the third quarter 2015. The sensors will be used by ... Jörgen Lantto, CEO of FPC, comments: " This order   ... smartphone OEMs in integrating touch fingerprint sensors in   their ...
(Date:6/15/2015)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the ... commerce market, announces that its leading payment security technology, the ... Experience! @ NYC June 18th. Digital Experience! @ ... in technology to over 300 of the top media covering ... Pavilion in New York City from ...
Breaking Biology News(10 mins):Synaptics Touchscreen and Display Driver IC Solutions Power Xiaomi's Latest Flagship Smartphones 2Synaptics Touchscreen and Display Driver IC Solutions Power Xiaomi's Latest Flagship Smartphones 3FPC Receives Order for Touch Fingerprint Sensors of 375 MSEK 2Wocket Smart Wallet Exhibiting at Pepcom Digital Experience! @ NYC June 18th 2Wocket Smart Wallet Exhibiting at Pepcom Digital Experience! @ NYC June 18th 3
... crash-car derby between heavy and light isotopes vying for the ... have an edge, research led by Case Western Reserve University ... igneous rocks form. As molten rock cools along a ... happens because hotter atoms move faster than cooler atoms and, ...
... release is available in German . ... increasing quantities as substitutes for CFCs, are also climatically very ... journal Science an international team of researchers recommends ... This could save the positive side effect of the Montreal ...
... An invasive plant may have saved an iconic Australian lizard ... according to research published in the March issue of The ... invasive species preparing local predators for the arrival of another, ... who led the research. Cane toads were ...
Cached Biology News:How heavy and light isotopes separate in magma 2How heavy and light isotopes separate in magma 3Protecting the climate by reducing fluorinated greenhouse gas emissions 2Protecting the climate by reducing fluorinated greenhouse gas emissions 3Invasive plant protects Australian lizards from invasive toad: Study 2
(Date:6/25/2015)... ... 25, 2015 , ... The American Brain Tumor Association announced ... Family Conference, Providing and Pursuing Answers: Advances in Research, Treatment and Care. The ... July 24-25, 2015. , “As advances in research accelerate the arrival of precision ...
(Date:6/25/2015)... , June 25, 2015  The Galien Awards Committee ... Genome Sciences and Medical Genetics at the University of ... Bono Humanum Award at the ninth annual Prix Galien ...   The Pro Bono Humanum Award recognizes ... the first woman recipient of the award.   ...
(Date:6/25/2015)... 2015 /PRNewswire/ - Portage Biotech Inc. ("Portage" or "the ... PTGEF,), is pleased to announce that it has completed ... approximately 36.8 million common shares at US$0.14 each. The ... closed on June 15, 2015 as per our press ... tranche closed on June 24, 2015. The Company is ...
(Date:6/25/2015)... 2015   Advaxis, Inc.  (NASDAQ: ADXS ), ... hold a business update conference call at 8:30 a.m. ... call is intended to provide Advaxis investors and stakeholders ... first half of 2015 and an overview of milestones ... 2016. A live broadcast of the conference ...
Breaking Biology Technology:Nationally Recognized Brain Tumor Experts to Speak at American Brain Tumor Association Patient and Family Conference 2The Prix Galien USA Awards Committee Selects Professor Mary-Claire King as 2015 Pro Bono Humanum Honoree 2The Prix Galien USA Awards Committee Selects Professor Mary-Claire King as 2015 Pro Bono Humanum Honoree 3Portage Completes Non-brokered Private Placement in Two Tranches for a Total Proceeds of US$ 5,155,080 2Portage Completes Non-brokered Private Placement in Two Tranches for a Total Proceeds of US$ 5,155,080 3Advaxis Provides 2015 Half-Year Review and Outlook 2Advaxis Provides 2015 Half-Year Review and Outlook 3Advaxis Provides 2015 Half-Year Review and Outlook 4Advaxis Provides 2015 Half-Year Review and Outlook 5Advaxis Provides 2015 Half-Year Review and Outlook 6Advaxis Provides 2015 Half-Year Review and Outlook 7Advaxis Provides 2015 Half-Year Review and Outlook 8
... MADISON, WI - KLAS Enterprises, a research and consulting ... Best Overall Vendor in its Top 20 Year-end Report ... on a confidential survey of CIOs, executives, managers, and ... in monitoring and reporting the performance of healthcare's information ...
... have datelined this column Chicago or Minneapolis, because last week ... the I-Q Corridor. It was a reminder that better days ... intellectual property, innovative spirit and investment capital four of ... interstate highway system that binds Chicago, Milwaukee, the Rockford-Beloit-Janesville area, ...
... of Commerce has announced that it is producing the ... on Thursday, September 25, from 8:30 a.m. to 3:45 ... Pewaukee. , ,Wisconsins medical device and technology cluster ... our state, said Department of Commerce (Commerce) Secretary Cory ...
Cached Biology Technology:Traveling the I-Q Corridor: Upper Midwest technology future is bright 2Traveling the I-Q Corridor: Upper Midwest technology future is bright 3Medical Technologies and Devices Symposium 2
HybriWell seals securely to a microscope slide surface in seconds to enclose single or multiple specimens in a small reagent volume and eliminate evaporation....
Comp Dim: chamber diam. depth 20 2.8 mm chamber maximum volume 720 μL...
... Human IgM Assay Kit to address the ... assay for Human IgM that eliminates the ... a simple mix-and-read assay that allows the ... ng/ml in approximately 30 minutes. The Pierce ...
AC input: 230 V...
Biology Products: