Navigation Links
Students invent protective pouch to enhance cell therapy

Johns Hopkins undergraduates have invented a device to improve cell therapy for diabetes patients by anchoring transplanted insulin-producing cells inside a major blood vessel.

A team of five seniors and two freshmen, working with Johns Hopkins doctors and engineers, devised a protective "pouch" that should fit inside the portal vein, which feeds into the liver. This pouch would keep microcapsules of therapeutic cells in one place, allowing them to thrive and send out needed insulin. The inventors say the same approach could be used in cell therapy for other ailments, including liver disease.

"I think it's a brilliant idea," said one of the project's sponsors, Jeff W. M. Bulte, director of the Cellular Imaging Section in the Johns Hopkins Institute for Cell Engineering.

The pouch is formed by sandwiching a porous band of nylon mesh between two concentric metal stents, similar to the ones used to keep clogged blood vessels open. Once the stents are in place, microcapsules filled with helpful cells are injected into the gap between the stents, where they become trapped within the nylon mesh. Blood flowing through the vessel should nourish the encapsulated cells and circulate the proteins, such as insulin, produced by these cells.

The project is important because it could lead to better results from cellular therapy, in which live cells are injected to repair or replace damaged or depleted tissue. "It’s a device," Bulte said, "that allows the microcapsules to be removed and reinserted if additional therapy is needed ?a ‘yearly refill,?for example ?and the students have provided an ideal environment in which the encapsulated cells can thrive."

Along with other undergraduate projects, this prototype was unveiled May 2 at the university’s Biomedical Engineering Design Day showcase. The Johns Hopkins Technology Transfer staff has applied for a provisional patent. Animal testing is expected to begin this summer. If it is succ
'"/>

Source:Johns Hopkins University


Page: 1 2 3 4

Related biology news :

1. Students discover 11,000 year old remains of Irish Elk
2. Wright bros. upstaged! Dinos invented biplanes
3. Eminent inventor of DNA fingerprinting gains new recognition
4. U of M researchers invent flashy new process to turn soy oil, glucose into hydrogen
5. Cancer-killing invention also harvests stem cells
6. Natural vitamin E tocotrienol reaches blood at protective levels
7. UC Davis researchers reveal apples protective ways
8. Gladstone investigators identify a new protective action for the powerful anti-HIV factor, APOBEC3G
9. Canadian study shows bilingualism has protective effect in delaying onset of dementia by four years
10. Amino acids in nectar enhance butterfly fecundity: A long awaited link
11. Pulsating ultrasound enhances gene therapy for tumors
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Students invent protective pouch enhance cell therapy

(Date:7/24/2014)... has different effects on different species of fish, ... of Bristol and Exeter which tested fish anti-predator ... a flying seagull predator model when exposed to ... European minnows. , Lead author Dr Irene ... "Noise levels in many aquatic environments have increased ...
(Date:7/24/2014)... sake brewery has its own microbial terroir, meaning the ... those found in the product, creating the final flavor ... journal Applied and Environmental Microbiology . This is ... of a sake brewery. , Many sake makers ... David A. Mills of the University of California, Davis, ...
(Date:7/24/2014)... this week for an all-day public forum on a ... (EPA) to dredge toxic sediment from an eight-mile stretch ... called the plan, which proposes removing 4.3 million cubic ... riverbed, one of the largest cleanups in the agency,s ... off-site. , "We need to ensure the future well-being ...
Breaking Biology News(10 mins):The microbes make the sake brewery 2Experts Weigh the Pros and Cons of a $1.7 Billion EPA Cleanup Plan for the Passaic River at an NJIT 2
... mandate communitywide water conservation measures, individualsparticularly homeownerscan make ... Hoping to provide urban planners with more information ... supplies, a team from New Mexico State University ... toward high desert plants. Rolston St. Hilaire, Dawn ...
... The Federation of American Societies for Experimental Biology (FASEB) ... the travel award recipients for the 2010 Society for ... Annual Meeting in Anaheim, California from September 30 ... promote the entry of underrepresented minority students, postdoctorates and ...
... Bethesda, MD FASEB MARC (Minority Access to Research ... the 2010 Societ Italiana di Patologia (SIP) XXX National ... These awards are meant to promote the entry of ... of the basic science community and to encourage the ...
Cached Biology News:Santa Fe homeowners weigh in on landscape preferences 2MARC Travel Awards announced for the 2010 SACNAS Annual Meeting 2
(Date:7/23/2014)... have made great strides in saving China,s endangered national ... over 65 giant panda reserves that have been established ... just 1596 pandas remain in the wild. , ... save the panda by improving genetic diversity, avoid inbreeding ... how are these high-profile programs doing so far? , ...
(Date:7/23/2014)... LOS ANGELES , July 23, 2014 /PRNewswire-iReach/ -- ... enhance cognitive performance for the long term. They are ... competitive edge of sustained energy as an alternative to ... launch Think Drinks on Indiegogo on July 29, 2014, ... the 30-day campaign. Photo - http://photos.prnewswire.com/prnh/20140723/129697 ...
(Date:7/23/2014)... Last year, Formedix celebrated ... global provider of data management solutions for clinical trials. ... system for electronic data capture (EDC) and clinical data ... study execution tools added TrialMaster to its Transform for ... of Transform for TrialMaster, is being released this week, ...
(Date:7/23/2014)... StemGenex® , the leading resource for ... at improving the lives of patients dealing with degenerative ... disease. StemGenex believes that a commitment to the ... when providing care to patients with degenerative diseases. ... accessible to the millions of individuals currently living with ...
Breaking Biology Technology:truBrain Neuroscientists To Launch More Effective, Healthier Alternative To Energy Drinks On Indiegogo 2Formedix and OmniComm Systems® Partnership Strengthened with the Release of Enhanced TrialMaster® Integration for EDC Build 2Formedix and OmniComm Systems® Partnership Strengthened with the Release of Enhanced TrialMaster® Integration for EDC Build 3StemGenex® Gives Hope to Parkinson’s Patients through New Stem Cell Clinical Study 2StemGenex® Gives Hope to Parkinson’s Patients through New Stem Cell Clinical Study 3
... 15 /PRNewswire-Asia-FirstCall/ -- American Oriental,Bioengineering, Inc. (NYSE: AOB ), ("the Company" or "AOBO"), ... prescription and over the counter ("OTC"),products, today announced financial results for the fourth quarter and fiscal,year ... ... ...
... ... and material testing, is taking strides to expand their Product and Material Testing Division by ... ... device package, product and material testing, is taking strides to expand their Product and Material ...
... that it has received a US Patent Office Notice of Allowance of patent claims which strongly protects the formation of cartilage by the unique NELL ... ... , , ... ...
Cached Biology Technology:American Oriental Bioengineering Reports Fourth Quarter and Full Year 2009 Financial Results 2American Oriental Bioengineering Reports Fourth Quarter and Full Year 2009 Financial Results 3American Oriental Bioengineering Reports Fourth Quarter and Full Year 2009 Financial Results 4American Oriental Bioengineering Reports Fourth Quarter and Full Year 2009 Financial Results 5American Oriental Bioengineering Reports Fourth Quarter and Full Year 2009 Financial Results 6American Oriental Bioengineering Reports Fourth Quarter and Full Year 2009 Financial Results 7American Oriental Bioengineering Reports Fourth Quarter and Full Year 2009 Financial Results 8American Oriental Bioengineering Reports Fourth Quarter and Full Year 2009 Financial Results 9American Oriental Bioengineering Reports Fourth Quarter and Full Year 2009 Financial Results 10American Oriental Bioengineering Reports Fourth Quarter and Full Year 2009 Financial Results 11American Oriental Bioengineering Reports Fourth Quarter and Full Year 2009 Financial Results 12DDL Expands the Product & Material Testing Division 2DDL Expands the Product & Material Testing Division 3Bone Biologics Announces a Major US Patent Issuance For Its Recombinant Protein Process For the Formation of Cartilage 2Bone Biologics Announces a Major US Patent Issuance For Its Recombinant Protein Process For the Formation of Cartilage 3
Collected from animals of U.S. origin.Collected from animals of U.S. origin. *Can be used in cell growth studies and immunoassays. *Sterility tested, * Mycoplasma tested upon request, *Endoto...
Fetal Calf Serum Replacement (Bistec) serum...
... reagent for Virus isolation ... unique water insoluble Elastomeric ... and chaotropes; Engineered to ... viruses while preserving infectivity; ...
Non-Receptor Tyrosine Kinase Sampler Kit 10 mu g each...
Biology Products: