Navigation Links
Stem cell transplants improve recovery in animal models for stroke, cerebral palsy

A single dose of adult donor stem cells given to animals that have neurological damage similar to that experienced by adults with a stroke or newborns with cerebral palsy can significantly enhance recovery from these types of injuries, researchers say.

Using a commonly utilized animal model for stroke, researchers administered a dose of 200,000-400,000 human stem cells into the brain of animals that had experienced significant loss of mobility and other functions. The stem cells used in the study were a recently discovered stem cell type, referred to as multipotent adult progenitor cells, or MAPCs.

Treated animals experienced at least 25 percent greater improvement in motor and neurological performance than controls, said Dr. Cesario V. Borlongan, neuroscientist at the Medical College of Georgia and the Veterans Affairs Medical Center in Augusta.

The findings are being presented April 7 during the 58th annual meeting of the American Academy of Neurology in San Diego.

In humans, the findings hopefully will translate to incremental but important recovery advances, said Dr. David Hess, adult stroke specialist, chair of the MCG Department of Neurology and a study co-author. "The single largest cause of disability among adults in ths U.S. is stroke," said Dr. Hess. "It's a huge public health problem in the world." He hopes one day stem cell therapy, along with aggressive physical therapy and possibly tPA can work synergistically to reduce that disability.

"These are not going to be cures, but this level of recovery is significant, and could help get somebody out of a bed and into a wheelchair or out of a wheelchair to walking with a cane or from a cane to walking unassisted. If somebody can go from a wheelchair to a cane that is a big improvement, that is how we look at it," Dr. Hess said.

Adult animals were tested across a range of standardized tasks both before and after undergoing the surgically induced stroke, and meas
'"/>

Source:Medical College of Georgia


Page: 1 2 3 4 5

Related biology news :

1. Pennsylvania researchers find liver transplants provide metabolic cure for rare genetic disease
2. Predicting successful outcomes in living-donor liver transplants
3. What animals can tell us about hemorrhage, organ transplants and aging
4. Leading reason for corneal transplants comes into focus
5. Protein may hold key to decreasing organ dysfunction rates in heart transplants
6. Stem cell transplants explored at Stanford as a possible treatment for hearing loss
7. Thymus transplants gives hope to babies with fatal immune disease
8. Discovery of key proteins shape could lead to improved bacterial pneumonia vaccine
9. Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells
10. Vascular structure and function improve with diet and exercise
11. Scientists discuss improved biopesticides for locust control in West Africa
Post Your Comments:
(Date:9/30/2014)... , Sept. 30, 2014  Spectra ... solutions for the biotech and power generation ... new RECONN Bioprocess Manager, an easy-to-use and ... geared towards bioprocess development laboratories. ... disparate bioreactor and analyzer systems. Accessing and ...
(Date:9/29/2014)... new study confirms that the exposure to tar tended ... of regular cigarettes. Similarly, exposure to nicotine tended ... popular type of cigarette in several countries around the ... certain toxic chemicals in the smoke of these cigarettes ... lower levels of chemicals in the smoke are not ...
(Date:9/29/2014)... CORVALLIS, Ore. Parents with children at home should ... from Oregon State University are recommending, after a new ... and asthma, asthma symptoms and chronic bronchitis. , "In ... the prevalence of asthma and wheezing is higher than ... ventilation," said Ellen Smit, an associate professor in the ...
Breaking Biology News(10 mins):Spectra Automation Introduces RECONN Bioprocess Manager 2Slim cigarette smokers not exposed to more harmful chemicals 2Childhood asthma linked to lack of ventilation for gas stoves, OSU study shows 2Childhood asthma linked to lack of ventilation for gas stoves, OSU study shows 3
... University of Texas Medical Branch at Galveston have identified women ... acetate, more commonly known as Depo-Provera or the birth control ... use DMPA will gain weight and will help physicians to ... 5 percent within the first six months of use, called ...
... research shows that training your brain may be just as ... injuries, and suggests a shift from performance-based to prevention-based athletic ... is one of the four major ligaments of the knee, ... well as an economic strain on the medical system. ...
... 2009 Scientists at Burnham Institute for Medical Research (Burnham) ... a major role in promoting programmed cell death (apoptosis), helps ... and invade surrounding tissues. The study was published in the ... team of scientists, led by Kristiina Vuori, M.D., Ph.D., professor ...
Cached Biology News:UTMB study identifies women at risk of gaining excessive weight with injectable birth control 2Knee injuries may start with strain on the brain, not the muscles 2Protein that promotes cancer cell growth identified 2
(Date:9/30/2014)... available in German . ... quantum dots in a semiconductor layer. Quantum dots are small ... processes. If a short laser pulse is fired at the ... dot experiences a change in the electromagnetic field around it. ... of light by the dot. As soon as the refractive ...
(Date:9/30/2014)... is available in German . ... Universitt Mnchen (TUM) have demonstrated a new kind of ... that future computer chips could be based on three-dimensional ... main enabling technology of the semiconductor industry CMOS ... TUM researchers and collaborators at the University of Notre ...
(Date:9/30/2014)... NEW YORK , Sept. 30, 2014 /PRNewswire/ ... Review - 2014 Summary Global Markets ... Review - 2014, provides an overview of the ... focus. This report provides comprehensive information on ... Biotechnology, LLC,s, complete with comparative analysis at various ...
(Date:9/30/2014)... Shimadzu Scientific Instruments has released the ... precise tool for measuring displacement in rubber and ... maximum movement distance, the DSES-1000 can measure elongations ... of 10 mm. In addition, it achieves +/- ... and within +/- 100 µm below 50-mm stroke. ...
Breaking Biology Technology:Ultrafast remote switching of light emission 2A new dimension for integrated circuits: 3-D nanomagnetic logic 2A new dimension for integrated circuits: 3-D nanomagnetic logic 3Pacific Northwest Biotechnology, LLC - Product Pipeline Review - 2014 2Pacific Northwest Biotechnology, LLC - Product Pipeline Review - 2014 3Shimadzu’s New Long-Travel Extensometer Increases Precision for Soft Material Testing 2
... 27, 2011 Life Technologies Corporation (NASDAQ: ... presentation to investors as part of the Morgan Stanley ... which is being held at the company,s headquarters in ...  David Hoffmeister, Life Technologies, Senior Vice President and Chief ...
... Thirty years after the first American baby from in ... replaced the limits of medical know-how as the chief reason ... Arizona,s largest fertility clinic. "Compared to the early ... greater," says Dr. Drew Moffitt, of Arizona Reproductive Medicine ...
... Fla., April 27, 2011 Dyadic International, Inc. ("Dyadic") ... the discovery, development, manufacture and sale of enzyme and ... industries, announced today that it has been issued U.S. ... by the United States Patent and Trademark Office ...
Cached Biology Technology:Life Technologies to Webcast Investor Presentation as Part of the Morgan Stanley West Coast Medtech and Life Science Tools Bus Trip 2Thirty Years After 1st American "Test-Tube Baby," Economy May Be Biggest Obstacle for Infertile Couples 2New U.S. Patent Issued to Dyadic International 2New U.S. Patent Issued to Dyadic International 3
Goat polyclonal to HA1 ( Abpromise for all tested applications). Antigen: Synthetic peptide: TLGSCRERQPEFV from the C terminus of human HA1. Entrez GeneID: 23526 Swiss Protein ID: O78181...
... Capture high-resolution chemiluminescent and bioluminescent ... High-sensitivity camera is cooled to subzero ... dynamic range for high quality images ... light-tight cabinet provides optimum conditions for ...
Goat polyclonal to Sarcosine Oxidase ( Abpromise for all tested applications). Antigen: Microbial Sarcosine Oxidase. Entrez Gene ID: 51268 Swiss Protein ID: Q6IAJ9...
odz, odd Oz/ten-m homolog 1 [Source:RefSeq_peptide;Acc:NP_055068] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
Biology Products: