Navigation Links
Stem cell training program to make its Stanford debut

Nature is a seemingly endless storehouse of interesting ?and potentially life-saving ?biological molecules. But tracking down and harvesting those chemicals in their natural form can be time-consuming, expensive and unreliable.

Now Salk scientists have discovered a new way of bringing “bio-prospecting?out of the rainforest and into the lab. Their findings are published in the June 16th edition of the journal Nature.

Stéphane Richard, Joseph Noel and Tomohisa Kuzuyama isolated and examined a totally new enzyme that can mix and match biological chemicals to create a wide range of different molecules that could be used as the basis for new drugs. The enzyme, named Orf2, takes chemical building blocks known as small aromatic molecules and changes them by adding a fat-like molecule called a prenyl group. That modification can have a huge impact on where the aromatic molecule goes within the cell, and what sort of effects it has when it reaches its target.

“When you make that so-called hybrid molecule, all the chemistry associated with the original compound changes,?said Noel. He explained that the addition of a prenyl group, also known as prenylation, produces a relatively large change in the chemical’s biological properties. “The molecule becomes a little bit more greasy, and so the kinds of targets that it might interact with change completely.?/p>

“We actually have in our hands now the ability to do things that a chemist might not be able to do, or if a chemist was able to do it, it could be expensive and time-consuming,?said Noel. “I think it’s a completely novel way to approach the whole area of bio-prospecting and new natural medicines.?/p>

The group was interested in manipulating the properties of small aromatic molecules because these bacteria- and plant-derived compounds are involved in a wide variety of important biological processes. Some are potent cancer-fighting anti-oxidants, while others have antibiotic or anti-fungal proper
'"/>

Source:


Page: 1 2 3

Related biology news :

1. Exercise training in ordinary people affects the activity of 500 genes
2. Laboratory professionals in Africa receive training under AIDS Relief Plan
3. Lance Armstrong through a physiological lens: hard training boosts muscle power 8%
4. Research finds music training tunes human auditory system
5. Critical role in programmed cell death identified
6. Harmful chemicals may reprogram gene response to estrogen
7. Modification of program enables prediction of gene transcription
8. Rutgers to lead $52.7 million protein research program
9. DOEs Office of Science sets up program to aid scientists displaced by Hurricane Katrina
10. Costly breeding programs for endangered species pay off
11. HIV-infected adults in Botswana respond positively to ARV therapy public treatment program
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Stem cell training program make its Stanford debut

(Date:3/26/2015)... TORONTO , March 26, 2015 ... premier family, social, recreation and athletic club, today announced ... designed to allow freedom of movement for members and ... "Following a comprehensive process, we selected FST,s IMID ... sophistication and convenience for our members and staff, in ...
(Date:3/24/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/hdgz7h/global_iris ... Iris Recognition Market 2015-2019" report to their offering. ... market to grow at a CAGR of 23.5 percent ... the present scenario and the growth prospects of the ... calculate the market size, the report considers the revenue ...
(Date:3/24/2015)... --Research and Markets ( http://www.researchandmarkets.com/research/kvdtcw/face_and_voice ) has announced the ... Business Report" report to their offering. This report ... Thousands by the following Segments: Face Biometrics, and Voice Biometrics. The ... , Japan , Europe ... & Africa , and Latin ...
Breaking Biology News(10 mins):Granite Club First Private Club in North America to Implement FST Biometrics Secure Access Solution, as Part of Multi-million Dollar Expansion 2Global Iris Recognition Market 2015-2019 with 3M Cogent, Bioenable Technologies, Cross Match Technology, Iris ID Systems & Safran Dominating 2Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 2Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 3Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 4Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 5Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 6
... have shown that some simple biodegradable liquids can stop ... could significantly impact medicine. , When the liquid, composed ... wounds, the peptides self-assemble into a nanoscale protective barrier ... the injury heals, the nontoxic gel is broken down ...
... Now, a St. Louis-area teenage boy and a computer ... conducted by a team of neurosurgeons, neurologists, and engineers ... boy, a 14-year-old who suffers from epilepsy, is the ... Invaders, using only the signals from his brain to ...
... study appearing in the forthcoming issue of The American ... Svata M. Louda (all of the University of Nebraska, ... eaten at the same rate. , Plant-insect ecologists ... quality or defective chemistry of plant tissues. However, the ...
Cached Biology News:MIT material stops bleeding in seconds 2MIT material stops bleeding in seconds 3Teenager moves video icons just by imagination 2Teenager moves video icons just by imagination 3
(Date:3/26/2015)... 2015 ReliantHeart, Inc., an innovative supplier ... supplier of precision transit-time flow measurement solutions, are collaborating ... the efficiency of the HeartAssist5® Left Ventricular ... experience greater mobility and peace of mind. , ... board, will draw 1/6th of the power required by ...
(Date:3/25/2015)... one of the most attractive in the emerging European ... growing economy and increasing government investment in healthcare, according ... market is set to grow at twice the pace ... 10-15% annually reaching an approximate market value of $43-60 ... Green Cross provides total healthcare solutions that address ...
(Date:3/25/2015)... March 25, 2015 The surging ... smartphones have fuelled social media growth, with over ... engaged in social networking. Insurance companies are making ... with clients and promote a diversity of their ... are increasingly exploiting social networking services as part ...
(Date:3/25/2015)... Mass. and REYKJAVIK, Iceland , ... capabilities for using the genome to create better medicine, today ... the largest studies of whole-genome data yet undertaken. ... Nature Genetics – are built around the most ... a team of deCODE scientists led by Kari Stefansson ...
Breaking Biology Technology:LVAD patients to have greater mobility and peace of mind through Transonic and ReliantHeart’s True Flow collaboration for the HeartAssist5® 2LVAD patients to have greater mobility and peace of mind through Transonic and ReliantHeart’s True Flow collaboration for the HeartAssist5® 3Social Media Role in Global Insurance Industry Examined by Timetric in New Market Research Report Published at MarketPublishers.com 2Social Media Role in Global Insurance Industry Examined by Timetric in New Market Research Report Published at MarketPublishers.com 3Landmark deCODE Studies Demonstrate the Power of Truly Big Genomics for Improving Medicine Worldwide 2
... California and AMSTERDAM, October 3, 2011 ... that the company successfully completed a recent, routine inspection ... and Drug Administration (FDA). Agendia received FDA 510(k) clearance ... 2007. It remains the first and only test of ...
... Biopharmaceuticals, Inc. (Inspiration) today announced that the European Medicines ... the Marketing Authorization Application (MAA) for Inspiration,s IB1001, a ... prevention of bleeding in individuals with hemophilia B.  In ... begin its regulatory review process of the MAA. ...
... GRAZ, Austria, September 30, 2011 ... attracts international attention with a big mile stone. ... validated CNAP blood pressure wave offers the possibility ... the recently released product innovation CNAP-PPV, proves to ...
Cached Biology Technology:Agendia Successfully Completes Bi-Annual FDA Inspection 2Inspiration Biopharmaceuticals Announces Acceptance of European Marketing Authorization Application for IB1001 for the Treatment of Hemophilia B 2Inspiration Biopharmaceuticals Announces Acceptance of European Marketing Authorization Application for IB1001 for the Treatment of Hemophilia B 3International Study Confirms CNSystems-Technology 2
One bottle containing 30 ml of protein solution and 0.1% sodium azide....
No description available in Ensembl Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
Used in May-Grunwald Giemsa stain....
Sheep polyclonal to Quinolone ( Abpromise for all tested applications). Antigen: Norfloxacin(N)conjugated to BSA...
Biology Products: