Navigation Links
Stem cell therapy shows promise in regenerating damaged muscle in heart attack patients

Heart attack patients who received an new intravenous adult stem cell therapy, Provacel? experienced a lower number of adverse events, such as cardiac arrhythmias, and had significant improvements in heart, lung and global function compared to those who received a placebo, according to six-month Phase I study data presented at the American College of Cardiology's Innovation in Intervention: i2Summit in New Orleans on March 25.

Rush was one of 10 premier cardiac centers across the country that participated in the 53-patient, double-blind, placebo-controlled trial. Among other findings, patients receiving Provacel were 75 percent less likely to experience an arrhythmic adverse event compared to those receiving placebo (9 % vs. 37%, p=0.025) and significantly more patients who received Provacel experienced improvement in their overall condition at six months as compared to those receiving placebo (42% vs. 11%, p=0.027).

Provacel is a preparation of adult stem cells pre-formulated for intravenous delivery by the drug's manufacture, Osiris Therapeutics. Patients were administered an infusion of either Provacel or placebo within 10 days of having a heart attack and are being followed for 2 years. To prevent bias, neither the patient nor the physician knows who received the stem cell treatment and who received placebo.

Rush principal investigator cardiologist Dr. Gary Schaer, head of the Rush Cardiac Catheterization Laboratory, says one reason the study results are so promising is that these stem cells can be used without tissue typing and do not trigger an immune response, and are available for every patient.

The mesenchymal stem cells (MSC) are found in the adult bone marrow and have the potential to develop into mature heart cells and new blood vessels. The MSC cells are derived from normal, healthy adult volunteer bone marrow donors and are not derived from a fetus, embryo or animal. Because they are in an early stage of developm
'"/>

Source:Rush University Medical Center


Page: 1 2

Related biology news :

1. Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
2. Columbia research lifts major hurdle to gene therapy for cancer
3. Combination therapy boosts effectiveness of telomere-directed cancer cell death
4. Gene therapy converts dead bone graft to new, living tissue
5. Study identifies predictors of HIV drug resistance in patients beginning triple therapy
6. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
7. Muscle-targeted gene therapy reverses rare muscular dystrophy in mice
8. New therapy for HIV/AIDS eliminates needles and excessive toxicity
9. New Treatment Rivals Chemotherapy For Lymphoma, Study Finds
10. Gene therapy for Parkinsons disease moves forward in animals
11. Pulsating ultrasound enhances gene therapy for tumors
Post Your Comments:
(Date:5/23/2013)... HOUSTON (May 23, 2013) A new report ... responsible for helping pupils engage in at least 60 ... school day. , No more than half of American ... hour of vigorous or moderate intensity physical activity daily, ... , "Because children are in school for nearly half ...
(Date:5/23/2013)... and fastest growing open-access publishers, announces the launch ... and Biotechnology . , A broad scope ... and Biotechnology will provide a single open-access ... research to be disseminated and discussed. , ... provide an open-science and interactive web platform for ...
(Date:5/22/2013)... 2013 U.S. Forest Service scientists are part of ... from the TKF Foundation, will examine how collaborative planning ... recover from tragedy. , The TKF Foundation announced today ... selected for grant funding. In addition to research on ... recovery and resiliency, the 3-year, $585,000 grant will contribute ...
Breaking Biology News(10 mins):Schools should provide students with daily physical activity, IOM recommends 2Frontiers launches new open-access journal in Bioengineering and Biotechnology 2'Landscapes of Resilience' to study how people use nature as a source of recovery 2
... 160 participants gathered this week for the seventh ... year,s topic, "Synthetic Biology," brought together scientists, engineers, ... and social issues surrounding the emerging field of ... molecular biology at Princeton University and this year,s ...
... 2009 -- A USDOE and USDA study concluded that ... cropland pasture could be converted from current uses to ... which biomass could be harvested for use as a ... monoculture from which substantial quantities of biomass are removed ...
... string of recent discoveries about the multiple health benefits of ... awareness of the huge numbers of people who are deficient ... of it as "nature,s antibiotic." On issues ranging from ... disease and even vulnerability to influenza, vitamin D is now ...
Cached Biology News:Synthetic biology offers new opportunities for interdisciplinary collaboration 2Switchgrass produces biomass efficiently 2Multiple health concerns surface as winter, vitamin D deficiences arrive 2Multiple health concerns surface as winter, vitamin D deficiences arrive 3
(Date:5/23/2013)... 2013  Verenium Corporation (Nasdaq: VRNM ), ... and commercialization of high-performance enzymes, today announced that ... present at two upcoming conferences. (Logo: ... the Second Annual Marcum LLP Microcap Conference on Thursday, ... New York City.  The presentation is scheduled to begin ...
(Date:5/23/2013)... South Korea , May 23, 2013 /PRNewswire/ ... with SillaJen, Inc., a private biotherapeutics and contract ... targeted biological products for cancer, announced today a ... in patients treated with the oncolytic and immunotherapeutic ... This research was published in the May ...
(Date:5/23/2013)... (PRWEB) May 23, 2013 ... ancestry tracing for people of African descent, today ... product offering. For people of all races, myDNAmix ... from five distinct populations: Indigenous Americas (Native American), ... India Subcontinent. , Originally launched in ...
(Date:5/23/2013)... Bed bugs compromised Penn State. ... confirmed it. Meanwhile, My Cleaning Products offered complimentary samples of ... the pests without using harmful chemical elements. , Based ... the affected building was actually a dormitory , My ... made on May 13 and bed bug presence was confirmed ...
Breaking Biology Technology:Verenium To Present At Two Upcoming Conferences 2Verenium To Present At Two Upcoming Conferences 3Pusan National University Announces Science Translational Medicine Publication Highlighting Landmark Demonstration of Functional Anti-Cancer Antibody Induction in Patients Following JX-594 Treatment 2Pusan National University Announces Science Translational Medicine Publication Highlighting Landmark Demonstration of Functional Anti-Cancer Antibody Induction in Patients Following JX-594 Treatment 3AfricanAncestry.com Rolls Out Improved MyDNAMix Admixture Test for People of all Races; Enhancements Increase Accuracy in Estimation of Ancestral Makeup 2AfricanAncestry.com Rolls Out Improved MyDNAMix Admixture Test for People of all Races; Enhancements Increase Accuracy in Estimation of Ancestral Makeup 3Penn State Dorm Infested with Bed Bugs, My Cleaning Products Offers Complimentary Sample of Bed Bug Spray to Help Bed Bug Victims 2
... Emphasis on Drug Development and Recent ... Private Equity ... (Nasdaq: LXRX ) announced several changes to the,composition of ... and the completion of a major strategic financing,with Invus, LP. ...
... Sept. 25 NanoBio(R) Corporation, a,biopharmaceutical company developing ... prevent serious infections, today announced,the addition of four ... Lyou-fu Ma, PharmD, Ph.D.; Susan Ciotti, Ph.D.; Robert ... NanoBio in developing and commercializing,its novel topical anti-infectives ...
... SeqWright, Inc., an international,leader in the field ... Applied Biosystems (ABI) to purchase ABI,s next generation,SOLiD(TM) ... to offer commercial access to the latest in ... between,SeqWright and ABI that grows stronger with time. ...
Cached Biology Technology:Lexicon Appoints Judith Swain, M.D. to Board of Directors 2Lexicon Appoints Judith Swain, M.D. to Board of Directors 3Lexicon Appoints Judith Swain, M.D. to Board of Directors 4NanoBio Expands Drug Development Team for Its Anti-Infective Products 2NanoBio Expands Drug Development Team for Its Anti-Infective Products 3SeqWright Unveils ABI SOLiD(TM) Next Generation Genetic Analysis System 2
...
DryStrip aligners, 4. Category: Electrophoresis Systems & Standards & Reagents, IEF & SDS-PAGE & 2-D Electrophoresis, Multiphor II Kits & Components and Accessories....
...
... PGE1-d4 contains 4 deuterium atoms at the ... is intended for use as an internal ... GC- or LC-mass spectrometry. PGE1 is the ... but it is virtually undetectable in the ...
Biology Products: