Navigation Links
Stem cell study for patients with heart attack damage seeks to regenerate heart muscle

Rush cardiologists are hoping that transplanted stem cells can regenerate damaged heart muscle in those who experience a first heart attack. The study involves an intravenous infusion of adult mesenchymal stem cells from healthy donor bone marrow that might possibly reverse damage to heart tissue.

A unique benefit of the stem cell product is that it is given to patients through a standard IV line. Other therapies require delivery to the site of the disease through catheterization or open surgical procedures, but this one is very simple and easy for the patient.

"A person who has had a single, severe heart attack may survive but can be left with substantial damage to the heart muscle as a result of the blood supply to the heart muscle being cut off during the heart attack. The damaged muscle inhibits the heart's overall ability to pump blood, leading to heart failure," said Rush principal investigator cardiologist Dr. Gary Schaer, head of the Rush Cardiac Catheterization Laboratory. Rush is the only center in Illinois participating in the trial. There are 15 other sites nationwide participating in the study.

He explained that mesenchymal stem cells (MSC) are found in the adult bone marrow and have the potential to develop into mature heart cells and new blood vessels. The MSC cells are derived from normal, healthy adult volunteer bone marrow donors and are not derived from a fetus, embryo or animal. Because they are in an early stage of development, it is believed that they do not trigger an immune response when placed in someone else's body.

Similar to Blood Type O, these MSCs are being used without tissue type matching to a specific patient.

Dr. Schaer says the cells are grown in culture to very high numbers, allowing a single donor's cells to treat thousands of patients. "The cells have the ability to expand, or multiply, under controlled conditions, and the expanded cells have the ability to develop into different types o
'"/>

Source:Rush University Medical Center


Page: 1 2 3

Related biology news :

1. Bioartificial kidney under study at MCG
2. W.M. Keck Foundation funds study of friendly microbes
3. Yellowstone microbes fueled by hydrogen, according to U. of Colorado study
4. Genome-wide mouse study yields link to human leukemia
5. Clam embryo study shows pollutant mixture adversely affects nerve cell development
6. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
7. Same mutation aided evolution in many fish species, Stanford study finds
8. Sequencing of marine bacterium will help study of cell communication
9. Genetically modified rice in China benefits farmers health, study finds
10. A new study examines how shared pathogens affect host populations
11. NYU study reveals how brains immune system fights viral encephalitis
Post Your Comments:
(Date:10/10/2008)...al School in Plymouth, UK, have carried out resear... a day recommended to children from health experts... childhood obesity. , Their research has been pu...rchives of Diseases in Childhood." , The results... the development of over 200 children in Plymouth ...
(Date:10/10/2008)... will be the focus of the Society for Nutrition Ed...event is just one small step in fighting world hun...he world and requires immediate attention in order...hunger and deficiencies. The Society for Nutrition...blic to get involved and make a difference in thei...
(Date:10/9/2008)...swire-FirstCall/ -- Synaptics(R),Incorporated (Nas...ce,solutions for mobile computing, communications,...t will report financial results for the first quar...fter the close of market. The,company will host a ...estors at 2:00 p.m. PT (5:00 p.m. ET) during which...
(Date:10/9/2008)...lecular Biology Laboratory (EMBL) have generated a...elopmental blueprint of a vertebrate. With a newly...st time track all cells for the first 24 hours in ...d into a three-dimensional, digital representation...t online issue of Science , grants many new insig...
Breaking Biology News(10 mins):Recommendations for children's exercise lacking say experts 2World Food Day brings attention to food security around the globe 2Synaptics to Report First Quarter Results on October 23 2Digital zebrafish embryo provides the first complete developmental blueprint of a vertebrate 2Cynthia Steedman Earns Health Care Fraud Investigator Accreditation 2678 1Cynthia Steedman Earns Health Care Fraud Investigator Accreditation 2678 2Doctors Groups Offer ADHD Guide for Parents 2675 1Doctors Groups Offer ADHD Guide for Parents 2675 2Doctors Groups Offer ADHD Guide for Parents 2675 3Kaiser Permanente Named Green Electronics Champion by EPA Green Electronics Council 2671 1Kaiser Permanente Named Green Electronics Champion by EPA Green Electronics Council 2671 2Kaiser Permanente Named Green Electronics Champion by EPA Green Electronics Council 2671 3Tobacco Free Kids Applauds Tyra Banks for Exposing the Ugly Truth About Smoking 2667 1Tobacco Free Kids Applauds Tyra Banks for Exposing the Ugly Truth About Smoking 2667 2
...iew of published data on use of human growth hormo...ynthetic hormone was associated with small changes...er clinically important outcomes. , Further, peop...de effects such as soft tissue swelling, joint pai...reast development. They were also somewhat more l...
...ternational research team has found evidence of th...illion years. , Upright stumps of fossilised trees...tate New York, more than a century ago. However, u...ooked like. , Two years ago, two fossils were f...s, with their trunk, branches, twigs and crown sti...
...hod of mass-producing disease-fighting antibodies ...esearch group at The University of Texas at Austin...d the new antibody-production approach to improve ...gs. Drug companies have used those more time- and...or treating rheumatoid arthritis, cancer and other...
...Xie, Ph.D., Associate Investigator, and Zhigang Ji...ie Lab, have published results showing that the mi...enewal of germline stem cells and somatic stem cel... Maintains Drosophila Ovarian Stem Cells," was pub... , MicroRNAs are single-stranded small RNA molec...
Other Biology News:Growth hormone is not the anti-aging bullet for healthy adults 2Growth hormone is not the anti-aging bullet for healthy adults 3Cheaper, better disease treatments expected from faster approach to developing antibodies 2
(Date:10/10/2008)...hed the Sixth Milestone in its Ofatumumab ...N, Denmark, October 10 /- G...d the sixth milestone for,ofatumumab (HuMax-CD20(R...SmithKline (GSK). A milestone payment of approxima...) was triggered by the first patient,receiving tre...
(Date:10/10/2008)...Oct. 10 /Xinhua-- Beike,Biotechnology...bal leader in,stem cell research and treatment thr...as signed eight separate mutual cooperation agreem...anding stem cell research organizations.,As part o...em Cell Expert,Advisory Committee" and a separate ...
(Date:10/10/2008)...RNewswire/ -- Twenty of Britain,s most,innovative ...bit their,ideas at the fifth annual SETsquared Par...eld at One Great George Street, London, from 8am o...m of technology innovators,in electronics, informa...Six companies will give 10-minute presentations to...
(Date:10/10/2008)...Newswire/ -- Takeda Pharmaceutical Company,Limited...earch and,Development Center, Inc., a wholly owned...ation that the U.S. Food and Drug Administration (...e alogliptin New Drug Application,(NDA) by the Pre...r 27,2008., "In our most recent discussion with ...
Breaking Biology Technology:Genmab Reaches Milestone in Ofatumumab Collaboration 2Stem Cell Leader Beike Signs 8 New Cooperation Agreements, Establishes Safety Monitoring Boards 2Stem Cell Leader Beike Signs 8 New Cooperation Agreements, Establishes Safety Monitoring Boards 3Creators of Britain's Innovation Economy to Showcase the Technologies of the Future at the Fifth SETsquared Partnership Showcase 2008 2Creators of Britain's Innovation Economy to Showcase the Technologies of the Future at the Fifth SETsquared Partnership Showcase 2008 3FDA Continues Review of Takeda's New Drug Application for Alogliptin (SYR-322), a DPP-4 Agent for Type 2 Diabetes 2
...st technology workplace -- from kids right out of ...ond -- found ourselves in a new and unpleasant pla... jobs that we wouldnt have remotely considered in ... may even have stayed at a less-than-sensational c...the job market has slowly improved, many of us hav...
... a pop biotech quiz to see if you know your biotec...iotech companies? How many of these companies sti...ndependent? ,While Im willing to bet that most o... right in the first question, very few will get al...nentech Biogen Genex The Genetics Institute Ce...
...onic stem cells in a UW-Madison lab. Photo courtes...tion on California,s ballot this November may affe...c stem cell research, experts say. If passed, the ...osition 71, will provide $3 billion in tax-free st...searchplacing the Golden State at the forefront of...
... has received a three-year Phase II small business...n from the National Institute for Environmental He...ment of a personal monitor for the measurement of ...onitors are designed to be small, sensitive, inexp...children. , ,Collaborators on the grant include th...
Other Biology Technology:Ten reasons to flee your Midwest technology employer 2Ten reasons to flee your Midwest technology employer 3Ten reasons to flee your Midwest technology employer 4Ten reasons to flee your Midwest technology employer 5The birth of biotech: San Francisco, Boston, Geneva or Chicago? 2The birth of biotech: San Francisco, Boston, Geneva or Chicago? 3The birth of biotech: San Francisco, Boston, Geneva or Chicago? 4The birth of biotech: San Francisco, Boston, Geneva or Chicago? 5The birth of biotech: San Francisco, Boston, Geneva or Chicago? 6The birth of biotech: San Francisco, Boston, Geneva or Chicago? 7Referendum may pull California to the forefront of stem cell research 2Referendum may pull California to the forefront of stem cell research 3Referendum may pull California to the forefront of stem cell research 4Referendum may pull California to the forefront of stem cell research 5
...ins on a 1x3 inch nitrocellulose-coated glass slid...ccording to Gene Ontology classification, are arra...itional control proteins and a specific chip layou...Ichip protein microarrays are high-density protein...
...ained in standard 96-well microtiter plates. Each ...000 clones per plate. After positive identificatio...bplate is screened with a single 96-well PCR to id... well are then plated on LB/Amp agar and the resul...
... designed for flexibility and routine operation. W...on lens, true hyperbolic quadrupole and high-speed...idest range of sample types and applications. New ...nts unique ShieldTorch System, which enables the 7...
...plate luminescence reader that is designed for the...minescence labels: Reporter gene assays luciferas...ce substrates (luminol, acridinium esters, dioxeta...s (cytotoxity and proliferation, intracellular Ca2...
Biology Products: