Navigation Links
Stem cell research - new cell lines

In an Australian first, UNSW researchers have developed three clones of cells from existing human embryonic stem cells. The breakthrough could lead to new treatments for diabetes, Parkinson's disease and spinal cord injury.

"This cloning of cells involves a new technique, which is a very accurate way of extracting and then growing a single cell," said UNSW Senior Lecturer Dr Kuldip Sidhu, who is leading the research and is based at the Diabetes Transplant Unit (DTU) at the Prince of Wales Hospital, a major teaching hospital of UNSW. "There has only been one report of cloning of cells from human embryonic stem cells anywhere else in the world ?in Israel."

By growing a human stem cell colony from a single cell, researchers are one step closer to deriving a homogenous population of cells of a particular type.

"There are about 230 different cell types in the body. All these cells are derived from three embryonic layers ?one which forms the brain and spinal cord, another which forms the guts and liver and a third which forms muscles and bones," he said. "We need to establish a recipe to derive each of these from human embryonic stem cells, so they can be transplanted straight into the affected area of a patient.

"The insulin-producing cells, which are derived from the layer which also forms the gut and liver are the holy grail for diabetes researchers," said Dr Sidhu. "That's because they are destroyed in type-1 diabetes, which affects at least 100,000 people in Australia. So far there is no cure for it.

"Human embryonic stem cell research offers a permanent answer to the problem. It gives the hope that we can produce a pure population of those cells in large numbers and transplant them into the patient."

The researchers are currently in the discovery phase, where they are trying to characterise the three clonal lines they have developed.

"It is too early to say anything about these clonal lines, but one of them is i nclined towards the cells which form the guts and liver," said Dr Sidhu.

Dr Sidhu and Professor Bernie Tuch, the Director of DTU have received a grant for US$140,000 for two years from the Juvenile Diabetes Research Foundation (JDRF) in the United States to continue their work.

The research comes as the Federal government's moratorium limiting the use of excess embryos ends.


'"/>

Source:University of New South Wales


Related biology news :

1. Columbia research lifts major hurdle to gene therapy for cancer
2. U of M researcher examines newly emerging deadly disease
3. NYU researchers simulate molecular biological clock
4. First atlas of key brain genes could speed research on cancer, neurological diseases
5. New research questions basic tenet of neuron function
6. Vital step in cellular migration described by UCSD medical researchers
7. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
8. UCSD researchers maintain stem cells without contaminated animal feeder layers
9. Why do insects stop breathing? To avoid damage from too much oxygen, say researchers
10. New protein discovered by Hebrew University researchers
11. First real-time view of developing neurons reveals surprises, say Stanford researchers
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/1/2016)... , Feb. 1, 2016  Today, the first ... (AHA) announced plans to develop a first of its ... power of IBM Watson. In the first application of ... IBM (NYSE: IBM ), and Welltok will create ... health assessments with cognitive analytics, delivered on Welltok,s health ...
(Date:1/25/2016)... , Jan. 25, 2016  Glencoe Software, the ... pharma and publication industries, will provide the data management ... Centre (NPSC). ... Phenotypic analysis measures ... whole organisms, allowing comparisons between states such as health ...
(Date:1/20/2016)... , Jan. 20, 2016   MedNet Solutions , ... entire spectrum of clinical research, is pleased to announce ... significant achievements are the result of the company,s laser ... iMedNet eClinical , it,s comprehensive, easy-to-use and highly ... --> Key MedNet growth achievements in 2015 ...
Breaking Biology News(10 mins):
(Date:2/8/2016)... --> ... oncology company developing next generation cancer therapeutics that ... that chairman emeritus of Tata Sons Limited, Mr ... as part of the first close of Invictus,s ... Capital and Aarin Capital. http://photos.prnewswire.com/prnh/20150923/766442 ) ...
(Date:2/8/2016)... 2016  BioElectronics Corporation (OTC Pink: BIEL), the ... that it is responding to a notice of ... and Exchange Commission posted on the agency website.  ... the Board of BioElectronics Corporation and the Edward ... The Fuqua School of Business, Duke University.   ...
(Date:2/8/2016)... ... February 08, 2016 , ... Franz Inc. , an ... technology, today announced the availability of AllegroGraph 6, the leading Semantic Graph Database ... Certified Technology Program (CCPT). AllegroGraph is the first Semantic Graph Database to ...
(Date:2/8/2016)... Inc. (NYSE: DPLO) announced today that its new website has gone live. On Thursday, Feb. 4, ... Visit the new site: www.diplomat.is ... ... ... "The goal was to reimagine the website and create a smarter, ...
Breaking Biology Technology: