Navigation Links
Stanford snake venom study shows that certain cells may eliminate poison

mast cells, while others, called wild-type mice, had normal mast cells. "We saw the same results in the wild-type mice that we saw before with just the one component, sarafotoxin 6b," said Metz. The mast cells were activated via a particular receptor they had on the cell surface and released the appropriate proteins, which, Metz said, went on to "degrade and thus eliminate the venom, or at least make it less toxic."

The wild-type mice were able to withstand 10 times the dosage of this venom than the mast cell deficient mice could, further indicating that the mast cells were reducing the impact of the venom. To test whether mast cells could also reduce the toxicity of venom from snakes that didn't contain toxins comparable to sarafotoxin 6b, Galli and Metz tested the venom of the western diamondback rattlesnake and the southern copperhead. Again, the mast cells conferred a distinct protective edge.

Testing the mast cell response even further, they also experimented with the venom from honeybees, with the same positive result. "The mast cells significantly limit not only the toxicity, but also the mortality associated with the venom," said Galli.

But Galli called the battle between predators with venom and their prey "a kind of evolutionary arms race." He and Metz suspect that, given the broad range of venoms that have been developed by snakes and other creatures, mast cells probably won't perform as well against every type of venom.

"We expect that there will be some snake venoms that either are not affected by mast cells at all or perhaps even elicit more pathology due to their ability to activate mast cells. It all depends on the balance between the positive and negative effects of the mediators released by mast cells in response to a particular venom," said Galli.

Galli and Metz are embarking on a systematic survey of animal venoms. As more is learned about the natural defenses the mammalian immune system has against ve
'"/>

Source:Stanford University Medical Center


Page: 1 2 3 4

Related biology news :

1. Same mutation aided evolution in many fish species, Stanford study finds
2. First real-time view of developing neurons reveals surprises, say Stanford researchers
3. Stem cells from brain transformed to produce insulin at Stanford
4. Stanford gut check shows diversity of intestinal ecosystem
5. Young Blood Revives Aging Muscles, Stanford Researchers Find
6. Stem cell training program to make its Stanford debut
7. Gene therapy for muscular dystrophy fixes frail muscle cells in animal model, Stanford study finds
8. Sooner is better with cochlear implants, Stanford scientist shows
9. Learning to love bacteria: Stanford scientist highlights bugs benefits
10. For one Stanford doctor, the beat goes on during open-heart surgery
11. Stanford study of owls finds link in brain between sight and sound
Post Your Comments:
(Date:9/19/2014)... shows that legume plants regulate their symbiotic relationship ... are transmitted through the plant structure from leaves ... bacteria-holding nodules in the roots. This collaborative study ... for Basic Biology, the Graduate University for Advanced ... Resource Science in Japan. , Legumes, an ...
(Date:9/18/2014)... September 18, 2014 New research into the Crimean-Congo ... a severe hemorrhagic disease in humans similar to that ... for CCHFV infection. This discovery has the potential to ... pathogen. , The research, reported in a ... and conducted by scientists at the Texas Biomedical ...
(Date:9/18/2014)... foliage season that prompts millions of Americans to undertake jaunts ... possibly last a little longer within a century, according to ... in some areas of the United States as summer temperatures ... the journal Global Ecology and Biogeography . For instance, ... the state tree of New Hampshire could change color ...
Breaking Biology News(10 mins):For legume plants, a new route from shoot to root 2Research milestone in CCHF virus could help identify new treatments 2Fall foliage season may be later, but longer on warmer Earth 2Fall foliage season may be later, but longer on warmer Earth 3Fall foliage season may be later, but longer on warmer Earth 4
... of Physics World is devoted to animal physics, ... skaters effortlessly skip across water leaving nothing but a small ... current understanding of the mechanisms adopted by the pond skater ... a mathematics graduate from the Massachusetts Institute of Technology spent ...
... able to self-assemble into a wide range of highly ... Through biomimicry - technological innovation inspired by nature ... version of self-assembling molecules. A key to accomplishing this ... the form and function of a protein is ...
... October 31, 2012 Scientists at The Scripps ... of an important set of enzymes. The new inhibitors, ... used to study the functions of enzymes known as ... regulate. Early tests in mouse macrophages suggest that DAGL-inhibiting ...
Cached Biology News:Pond skating insects reveal water-walking secrets 2Folding funnels key to biomimicry 2Folding funnels key to biomimicry 3New inhibitors of elusive enzymes promise to be valuable scientific tools 2New inhibitors of elusive enzymes promise to be valuable scientific tools 3
(Date:9/19/2014)... , September 19, 2014 ... and Markets ( http://www.researchandmarkets.com/research/b2jxhs/micro_market ) has announced the addition ... Chromatography Columns"  report to their offering.  ... market is one of the fastest-growing segments in ... $1.2 billion in 2013, and expected to reach ...
(Date:9/18/2014)... BELLINGHAM, Washington, USA (PRWEB) September 18, 2014 ... of Representatives of a bill designed to stimulate development ... high-value jobs is being praised by leaders of ... The bill, the Revitalizing American Manufacturing and Innovation (RAMI) ... vote. The bill’s authors have said they are optimistic ...
(Date:9/18/2014)... , Sept. 18, 2014 /PRNewswire-iReach/ -- DeepResearchReports.com adds ... Acetic Acid Industry" and "2014 Deep Research Report ... to its research database. Photo - ... Research Report on Global and China Acetic Acid ... on China and Global ...
(Date:9/18/2014)... Ireland , September 18, 2014 ... and Markets ( http://www.researchandmarkets.com/research/czvg3s/biocompatible ) has ... "Biocompatible Materials - Global Strategic Business ... ,     (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ,This report analyzes ... in US$ Million by the following ...
Breaking Biology Technology:Micro Market Monitor : Global Pre-packed Chromatography Columns 2House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 2House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 3Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 2Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 3Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 4Biocompatible Materials - Global Strategic Business Report 2014 2Biocompatible Materials - Global Strategic Business Report 2014 3
... 16 Scientists at Biomodels have successfully ... treatment-relat e d fatigue (CTRF). The ... independent of anemia or weight loss and persists long after cancer ... will be presented today at the American Association for Cancer Research-NCI-EORTC ...
... Nov. 16 Neogen Corporation (Nasdaq: NEOG ) today announced ... With the split, shareholders of record on Nov. 30, 2009, will ... , The stock split will be effected in the form ... common stock on Dec. 15, 2009. As of today, Neogen has ...
... 16 Cornerstone Therapeutics Inc. (Nasdaq CM: CRTX), a ... significant products primarily for the respiratory and related markets, ... Chief Financial Officer, will be presenting a corporate overview ... at 9:00AM EST on Wednesday, November 18, 2009 ...
Cached Biology Technology:Biomodels Scientists Report Development of a Novel Model for Cancer Treatment-Related Fatigue 2Neogen Announces 3 for-2 Stock Split 2Cornerstone Therapeutics to Present at the 6th Annual Lazard Capital Markets Healthcare Conference 2
BD BioCoat Laminin 100 mm Culture Dishes, tissue-culture treated polystyrene with a uniform application of mouse laminin....
...
... is used as an internal standard for ... dilution mass spectrometry. 5-OxoETE is a polyunsaturated ... 5-HETE in human neutrophils. It stimulates cytosolic ... of 2 nM. 5-OxoETE selectively stimulates the ...
Mouse monoclonal antibody raised against a full length recombinant ATF3. NCBI Entrez Gene ID = ATF3...
Biology Products: