Navigation Links
Stanford doctors advance in bid to turn mice stem cells into blood vessels

Researchers at the Stanford University School of Medicine have taken a first step toward growing blood vessels from stem cells that could eventually be transplanted into living organisms.

Starting with embryonic stem cells derived from mice, surgical resident Oscar Abilez, MD, and colleagues have successfully differentiated the stem cells into myocytes, one of the building blocks of blood vessels, after placing them in a life-like growth environment that the research team had created. The scientists hope to be able to eventually grow whole blood vessels that can be transplanted back into mice.

The work is being performed in the laboratory of Christopher Zarins, MD, professor of surgery.

"It's very odd," Abilez said. "We get these stem cells and grow them into contracting myocytes in cultures: You really see them contracting, you really know they're alive, and you start to believe this stem cell stuff has possibilities."

For the study, Abilez received first place in the seventh annual International Society of Endovascular Fellows' research award in laboratory sciences. The findings are published in this month's edition of the Journal of Endovascular Therapy.

The ultimate goal of the research is to bring together two of today's most promising areas of medical investigation: stem cell research and tissue engineering. Tissue engineering, the growth of organs and tissues outside the body for replacement, has achieved successful transplantations of a variety of human tissues including skin and corneas. Most recently, a team of researchers at Wake Forest University in Winston-Salem, N.C., performed the successful transplantation of laboratory-grown bladders into seven children.

Tissue-engineered blood vessels have also seen some success when transplanted into animal models, but still face a variety of limitations, Abilez said, key among them rejection by the immune system. By creating a tissue-engineered blood vessel grown fro
'"/>

Source:Stanford University Medical Center


Page: 1 2 3

Related biology news :

1. Same mutation aided evolution in many fish species, Stanford study finds
2. First real-time view of developing neurons reveals surprises, say Stanford researchers
3. Stem cells from brain transformed to produce insulin at Stanford
4. Stanford gut check shows diversity of intestinal ecosystem
5. Young Blood Revives Aging Muscles, Stanford Researchers Find
6. Stem cell training program to make its Stanford debut
7. Gene therapy for muscular dystrophy fixes frail muscle cells in animal model, Stanford study finds
8. Sooner is better with cochlear implants, Stanford scientist shows
9. Learning to love bacteria: Stanford scientist highlights bugs benefits
10. For one Stanford doctor, the beat goes on during open-heart surgery
11. Stanford study of owls finds link in brain between sight and sound
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Stanford doctors advance bid turn mice stem cells into blood vessels

(Date:9/21/2014)... the University of California, San Diego, have developed a ... control the activity of genes based on sequences of ... its application to human embryonic cells in a paper ... , "All of our cells have the same blueprint, ... John Whitaker, lead author of the report. "Skin cells ...
(Date:9/21/2014)... as mussels and barnacles secrete very sticky proteins that ... underwater. Inspired by these natural adhesives, a team of ... used to repair ships or help heal wounds and ... the MIT researchers engineered bacteria to produce a hybrid ... as a bacterial protein found in biofilms slimy ...
(Date:9/19/2014)... by researchers from several Harvard University labs in ... and aspiring researchers with the intellectual raw materials ... from soft, flexible materials. , With the advent ... advances in manufacturing technology, soft robotics is emerging ... from conventional rigid robot design, but working with ...
Breaking Biology News(10 mins):Program predicts placement of chemical tags that control gene activity 2Engineered proteins stick like glue -- even in water 2Engineered proteins stick like glue -- even in water 3Soft robotics 'toolkit' features everything a robot-maker needs 2
... 12, 2009)The Society of Interventional Radiology hailed the ... in support of clinical patient management by vascular ... the critical contribution these minimally invasive specialists bring ... of ACR,s Resolution 22 is a continued endorsement ...
... This release is available in German . ... because of the limited amount of fossil fuels available, ... and other plant waste, are becoming the focus of ... the conversion of biomass into bio-oil, a highly promising ...
... Nlets Network and Hosting Services Enhances Law Enforcement ... Inc. (OTC Bulletin Board: BKYI), a leader in ... today announced a strategic partnership with Nlets. Nlets ... data communications network for the exchange of law ...
Cached Biology News:Interventional radiology: From sidelines to mainstream for patients 2Biomass as a source of raw materials 2BIO-key(R) Enters Strategic Partnership With Nlets 2BIO-key(R) Enters Strategic Partnership With Nlets 3
(Date:9/22/2014)... TORONTO , Sept. 22, 2014 ... announced that it has entered into a collaboration ... UHN,s Centre for Molecular Design and Preformulations (CMDP) ... The goal of the project is to increase ... proprietary buccal insulin spray product, thereby reducing the ...
(Date:9/22/2014)... 2014 METTLER TOLEDO is pleased ... measuring device CNS110 ScanTape™ . Replacing a ... offering greater ease and accuracy for transport and ... significantly enhance productivity—an important benefit for load planning ... equals profits. , Usable at any point ...
(Date:9/21/2014)... Chemical Sciences play a significant ... clean air and safe water, healthy food, and ... environmentalists, food scientists, educators, and scientists have a ... field of Chemistry for the national development, and ... of the fastest emerging Sciences, accelerating with a ...
(Date:9/19/2014)... is rarely simple. From crop yields to disease risks, ... those considered "complex traits." Just as for heightthe textbook ... particular human disease are shaped by multiple genetic and ... involved. To track down such genes, geneticists typically mate ... large mouse and a small mouseand then study their ...
Breaking Biology Technology:Generex Collaborates with University Health Network for Buccal Insulin Project 2Generex Collaborates with University Health Network for Buccal Insulin Project 3Generex Collaborates with University Health Network for Buccal Insulin Project 4ScanTape™ Handheld Dimensioner Increases Processing Volume 2Chemistry for Global Development during the Open Access Week 2Chemistry for Global Development during the Open Access Week 3Want to link genes to complex traits? Start with more diversity 2
... Company Selected to Participate in Gastroenterology Panel Discussion, ... ) announced today that Chief Executive Officer Elkan R. ... 2007 RBC Capital Markets Healthcare Conference taking place December ... Times Square in New York, New York.,The panel is ...
... Dec. 10 Lexicon,Pharmaceuticals, Inc. (Nasdaq: LXRX ) ... participate in the RBC Capital Markets,Healthcare Conference panel Going ... Westin Times Square Hotel in New York, New York ... A live audio webcast of the panel presentation ...
... Harrisburg Regional Education Consortium Promoting Advanced Technology,Industries ... High school and,college students from the Harrisburg ... and curriculum through a special collaboration,between several ... BioTech Day 2007, hosted by the Harrisburg ...
Cached Biology Technology:Pharmos Corporation to Present at the 2007 RBC Capital Markets Healthcare Conference 2Lexicon Pharmaceuticals to Present at RBC Capital Markets Healthcare Conference 2Capital Area Biotechnology Partnership Receives $160,000 State Investment 2
... dispenser combining the most versatile features for bulk ... existing Multidrop dispensers. , ,It is designed ... nl up to 2500 l with excellent precision ... for multiple plate formats (96, 384, 1536) including ...
... Multidrop Combi is a new generation bulk ... flexibility and simplicity for pharmaceutical and biotech ... reliable Multidrop range, Multidrop Combi has been ... volumes of 0.5-2500 l and multiple plate ...
Multidrop DW is a high-speed automated dispenser for Deep Well plates, 1.1 ml test tubes and 96-well plates. Designed for accuracy and precision, the Multidrop DW dispenses up to eight different reag...
Buckets for 2 racks of 5 tubes, type Stago/Hitachi...
Biology Products: