Navigation Links
St. Jude study solves mystery of mammalian ears

Protein motor in cochlea hair cells dominates the process of sound amplification in the mammalian ear, while movement of the cilia atop those cells dominates the response in non-mammals

A 30-year scientific debate over how specialized cells in the inner ear amplify sound in mammals appears to have been settled more in favor of bouncing cell bodies rather than vibrating, hair-like cilia, according to investigators at St. Jude Children’s Research Hospital.

The finding could explain why dogs, cats, humans and other mammals have such sensitive hearing and the ability to discriminate among frequencies. The work also highlights the importance of basic hearing research in studies into the causes of deafness. A report on this work appears in the advanced online issue of “Proceedings of the National Academy of Science.”

“Our discovery helps explain the mechanics of hearing and what might be going wrong in some forms of deafness,” said Jian Zuo, Ph.D., the paper’s senior author and associate member of the St. Jude Department of Developmental Neurobiology. “There are a variety of causes for hearing loss, including side effects of chemotherapy for cancer. One strength of St. Jude is that researchers have the ability to ask some very basic questions about how the body works, and then use those answers to solve medical problems in the future.”

The long-standing argument centers around outer hair cells, which are rod-shaped cells that respond to sound waves. Located in the fluid-filled part of the inner ear called the cochlea, these outer hair cells sport tufts of hair-like cilia that project into the fluid. The presence of outer hair cells makes mammalian hearing more than 100 times better than it would be if the cells were absent.

As sound waves race into the inner ear at hundreds of miles per hour, their energy—although dissipated by the cochlear fluid—generates waves in the fluid, somewhat like the tiny waves made
'"/>

Source:www.stjude.org


Page: 1 2 3

Related biology news :

1. Bioartificial kidney under study at MCG
2. Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
3. W.M. Keck Foundation funds study of friendly microbes
4. Yellowstone microbes fueled by hydrogen, according to U. of Colorado study
5. Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs
6. UCLA Study Shows One-Third of Drug Ads in Medical Journals Do Not Contain References Supporting Medical Claims
7. Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
8. Study Links Ebola Outbreaks To Animal Carcasses
9. Genome-wide mouse study yields link to human leukemia
10. Breakthrough Microarray-based Technology for the Study of Cancer
11. NYU Study Reveals How Brains Immune System Fights Viral Encephalitis
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Jude study solves mystery mammalian ears

(Date:10/29/2014)... food, but they also need protection from its harmful rays, ... molecules in plants that shields them from sun damage. Now, ... Chemical Society , one team reports on the mechanics of ... colleagues at Purdue University note that the harsh ultraviolet radiation ... plant DNA and, as a result, hinder plant growth. ...
(Date:10/29/2014)... decompose, their types and numbers of bugs and ... mean the difference between a closed case and ... using a more than $866,000 U.S. Department of ... these changing populations. The microbial communities may provide ... gender, race, socioeconomic relations and more, said Eric ...
(Date:10/29/2014)... MA and Hebei, China — BGI Tech and Hebei ... of the Jujube genome. Jujube is the most economically ... genome is particularly difficult to sequence due the high ... the first time that a genome in the Rhamnaceae ... recently published in Nature Communications . ...
Breaking Biology News(10 mins):MSU partners with Detroit to investigate death scenes 2BGI Tech and Hebei Agricultural University complete the genome sequencing of the jujube tree 2
... human health in the past, and are bound to ... for example, led to many illnesses and deaths from ... people vying for scarce food, shelter, and work. ... health ramifications. Following a request from Gov. Christine Gregoire, ...
... -- A slightly greater number of males than females are ... still more baby boys born than girls, there has been ... newborns in several industrialized countries, including Canada, Denmark, England, Germany, ... ask: Are there any factors that can influence the probability ...
... who have lower-pitched voices have more children than do ... their study suggests that for reproductive-minded women, mate selection ... in Biology Letters, offers insight into the evolution of ... our mates. In previous studies, David Feinberg, assistant ...
Cached Biology News:University and state agencies to forecast local health effects of climate change 2University and state agencies to forecast local health effects of climate change 3University and state agencies to forecast local health effects of climate change 4Weight gain between first and second pregnancies associated with increased odds of male second child 2
(Date:10/30/2014)... San Diego, CA (PRWEB) October 30, 2014 ... company announced today that they have manually curated public ... Pharma and non profit customers. the data is ... BioSciences manually curates and unifies public and internal data ... more value and knowledge out of the data that ...
(Date:10/30/2014)... 30, 2014 Grace Century portfolio project, ... Manganello, Chairman of the Board, to the National Stem ... appointment was made by the Ministry of Health on behalf ... , More than a year after Bahamian Parliament ... Prime Minister Perry Christie said the government has completed the ...
(Date:10/30/2014)... severe flooding that devastated a wide swath of Colorado ... bridges, roads and other infrastructure had been upgraded or ... of Colorado Denver. , "People need to understand the ... associate professor of structural engineering at the CU Denver ... the study. "There is an assumption that a bridge ...
(Date:10/27/2014)... -- Kalorama Information says that PCR is demonstrating its ... the United States and is the dominant ... the FDA,s Emergency Use Authorization (EUA) to authorize the emergency ... of the Ebola virus was an indication that the ... IVD industry and its biennial survey on diagnostics markets ...
Breaking Biology Technology:Rancho BioSciences Manually Curated TCGA Data Sets Available 2Grace Century’s Stem Cell Biobank Project Announces Chairman’s Appointment to National Stem Cell Ethics Committee of The Bahamas 2Grace Century’s Stem Cell Biobank Project Announces Chairman’s Appointment to National Stem Cell Ethics Committee of The Bahamas 3CU Denver study says upgrading infrastructure could reduce flood damage 2Kalorama: PCR The Go-to Test in Ebola Fight 2Kalorama: PCR The Go-to Test in Ebola Fight 3
... 2012 The Houston Technology Center (HTC), ... annual gala, "A Celebration of Entrepreneurs . " ... significant impact on the region,s economy; and developed lifesaving ... named Beth Williams, CEO of TechTrans International, Inc., as ...
... 21, 2012  Neuralstem, Inc. (NYSE MKT: CUR) announced ... at the World Stem Cells & Regenerative Medicine ... May 22nd at 12:30 PM. Mr. Garr,s presentation, ... Neuralstem,s cellular therapy trial in ALS, its neurogenic ...
...  Intellect Neurosciences, Inc. (OTCPK: ILNS) announces that Dr. ... will be presenting at the Seventh Annual Neurotech ... http://photos.prnewswire.com/prnh/20111214/NY22484LOGO ) The title of ... Attractive Targets for Active and Passive Immunotherapy." His ...
Cached Biology Technology:Leading Technology Incubator Honors Extraordinary Entrepreneurs 2Leading Technology Incubator Honors Extraordinary Entrepreneurs 3Neuralstem CEO to Present at the World Stem Cells and Regenerative Medicine Congress in London 2Intellect Neurosciences, Inc. to Present at Neurotech Investing and Partnering Conference 2Intellect Neurosciences, Inc. to Present at Neurotech Investing and Partnering Conference 3
... The Vibratome Company has joined forces with ... the Vibratome 411301 Tissue Chopper. This tissue ... sections of tissue for metabolic experiments and ... irregular specimens available at biopsy or from ...
... The Vibratome Company has joined forces ... introduce the Vibratome 800 Tissue Chopper. This ... prepare sections of tissue for metabolic experiments ... and irregular specimens available at biopsy or ...
... design, The Bioactive peptides are molecules of ... biological behaviour or activity which can be ... diagnostic, chemical and agro-food applications. In this ... peptides with superior properties for therapeutic applications. ...
... within neurons in vesicles called synaptosomes. ... synaptic bouton. Synaptosomes may be ... other cellular debris. Abnormalites in neurotransmitter ... pathological condtions. Conditions of release ...
Biology Products: