Navigation Links
Spiders help scientists discover how muscles relax

Using muscle tissue from tarantulas, an HHMI international research scholar and his colleagues have figured out the detailed structure and arrangement of the miniature molecular motors that control movement. Their work, which takes advantage of a new technique for visualizing tissues in their natural state, provides new insights into the molecular basis of muscle relaxation, and perhaps its activation too.

"We have solved the structure of the array of miniature motors that form our muscles and found out how they are switched off," said Raul Padron, a HHMI international research scholar in the Department of Structural Biology at the Venezuelan Institute for Scientific Research (Instituto Venezolano de Investigaciones Cientificas or IVIC) in Caracas, Venezuela.

The findings are reported in the August 25, 2005, issue of the journal Nature.

Padron and his colleagues focused their studies on striated muscle--the type of muscle that controls skeletal movement and contractions of the heart. Striated muscles are made of long cylindrical cells called muscle fibers. Within the fibers, millions of units known as sarcomeres give rise to movement of skeletal muscles. Sarcomeres are composed mainly of thick filaments of myosin, the most common protein in muscle cells, responsible for their elastic and contractile properties. The thick filaments are arranged in parallel with thin filaments of another muscle protein, actin. When the actin and myosin filaments slide along one another, the muscle contracts or relaxes.

Padron's study focused on the long, rod-shaped myosin of the thick filaments. The heads of these myosin rods project outward from the thick filament to connect with and move actin filaments during contraction of a muscle.

The structural studies were done using tarantula striated muscle, which the team has been studying since the 1980s. Striated muscles from the large, hairy spiders contain filaments that are particularly well o
'"/>

Source:Howard Hughes Medical Institute


Page: 1 2 3

Related biology news :

1. Wisconsin scientists grow critical nerve cells
2. UCSB scientists probe sea floor venting to gain understanding of early life on Earth
3. UAB scientists discover the origin of a mysterious physical force
4. Fox Chase Cancer Center scientists identify immune-system mutation
5. Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.
6. U-M scientists find genes that control growth of common skin cancer
7. UCLA scientists transform HIV into cancer-seeking missile
8. RNA project to create language for scientists worldwide
9. Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals
10. To control germs, scientists deploy tiny agents provocateurs
11. Leprosy microbes lead scientists to immune discovery
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Spiders help scientists discover how muscles relax

(Date:4/27/2015)... more than four decades, AUVSI,s Unmanned Systems ... event for the unmanned land, sea, and air industries. ... local, national, or trade news organization interested in gathering ... applications of unmanned technologies. The conference will explore the ... and how it will soon impact the lives of ...
(Date:4/20/2015)... 2015 Huntington Memorial Hospital is the first ... new miniaturized, wireless monitoring sensor to manage heart failure ... only FDA-approved heart failure monitoring device that has been ... physicians to manage heart failure. The CardioMEMS ... the pulmonary artery (PA) during a non-surgical procedure to ...
(Date:4/14/2015)... Conn. , April 14, 2015 NXT-ID, ... a biometric authentication company focused on the growing mobile ... been nominated for the 2015 New York Design Awards ... The Design100, New York City Design Awards are part ... based on over 2,500 ratings from the marketplace, industry ...
Breaking Biology News(10 mins):UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 2UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 3UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 4UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 5Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 2Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 3NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 2NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 3
... non-human primates, over 100 billion nerve cells build up ... an attempt is made to perform gene therapy for ... specify a responsible neural circuit out of many complicated ... a target gene into this particular circuit selectively. The ...
... and Germany have developed an open-source software that will ... software, named BioImageXD, will help in analysing cell and ... been funded by the Academy of Finland (through the ... the Finnish Funding Agency for Technology and Innovation. Version ...
... to Research Careers) Program has announced the travel award ... Society in San Diego, CA from August 5-8, 2012. ... of underrepresented minority students, postdoctorates and scientists into the ... the participation of young scientists at The 26th Annual ...
Cached Biology News:Transgenic technique to 'eliminate' a specific neural circuit of the brain in primates 2Researchers develop new method for analyzing cell function 2
(Date:5/5/2015)... May 5, 2015  Renova™ Therapeutics, a biopharmaceutical ... failure and other chronic diseases, has engaged RAND ... designed to reflect the healthcare patterns of multiple ... will be used to characterize the impact the ... on those groups of patients and the overall ...
(Date:5/5/2015)... -- A group of biotechnology executives and medical doctors announced ... non-profit organization dedicated to providing education, research and therapeutic ... consciousness.  ... Coma is the ... actions can be initiated by the patient, and sleep-wake ...
(Date:5/5/2015)... --Research and Markets ( http://www.researchandmarkets.com/research/x5gjj3/clinical ) ... Laboratory, Molecular Diagnostics and Genomic Testing Services Market ... Version" report to their offering. ... molecular diagnostics and pharmacogenics hold the promise of ... is moving out of the national and regional ...
(Date:5/5/2015)... , May 5, 2015  Orexigen Therapeutics, Inc. ... the first quarter 2015 on Friday, May 8 before ... a live webcast and conference call at 8:30 a.m. ... live call may be accessed by phone by calling ... 39586962. The webcast can be accessed live on the ...
Breaking Biology Technology:RAND Health Advisory Services modeling heart failure patient outcomes to inform potential impact of Renova Therapeutics lead product candidate 2RAND Health Advisory Services modeling heart failure patient outcomes to inform potential impact of Renova Therapeutics lead product candidate 3Biotechnology Executives and Medical Doctors Team Up to Tackle Coma and Disorders of Consciousness 2Biotechnology Executives and Medical Doctors Team Up to Tackle Coma and Disorders of Consciousness 3Biotechnology Executives and Medical Doctors Team Up to Tackle Coma and Disorders of Consciousness 4Biotechnology Executives and Medical Doctors Team Up to Tackle Coma and Disorders of Consciousness 5Global Clinical Laboratory, Molecular Diagnostics and Genomic Testing Services Market Trends and Forecast 2015 to 2019 2
... the Pain Clinic,Monitor, a new audit of Pain Clinics, ... reporting and analysis. First quarter 2008 results are now,available, ... and why, treatments received in the office, drugs discontinued,and ... Monitor is a monthly audit of a balanced selection ...
... Excess of $25 Million; Access Gains Second Source ... And Significant Clinical Trial Support, DALLAS and NANJING, ... ACCP) and Jiangsu Aosaikang,Pharmaceutical Co., LTD. ("ASK"), a premier ... market, today announced the,signing of a definitive licensing agreement ...
... Mass, June 4 Idenix,Pharmaceuticals, Inc. (Nasdaq: IDIX ... overview at the Seventh Annual Needham and,Company, LLC Biotechnology ... 3:30 pm. ET at The New York Palace Hotel ... webcast of the company presentation can be,accessed under "Calendar ...
Cached Biology Technology:WWMR, Inc. Announces Launch of New Pain Clinic Monitor 2WWMR, Inc. Announces Launch of New Pain Clinic Monitor 3Access Licenses ProLindac(TM) to Jiangsu Aosaikang Pharmaceutical Co., LTD., a Leading Oncology Pharmaceutical Company for Manufacturing, Development and Commercialization in the Greater China Region 2Access Licenses ProLindac(TM) to Jiangsu Aosaikang Pharmaceutical Co., LTD., a Leading Oncology Pharmaceutical Company for Manufacturing, Development and Commercialization in the Greater China Region 3
... handy dispensers save space and ... hats, and other garb. They ... bins for small parts used ... Clear acrylic. Open-slot design for ...
... Agilent Technologies introduces an enhanced ... ICP-MS for Windows 2000 and ... From September 2003, all new ... controlled by the new ChemStation ...
... save space and organize gloves, safety ... They are the perfect benchtop storage ... labs, processing and manufacturing. Clear static-dissipative ... particles they attract. Many other sizes ...
... critical to the maintenance of appropriate ... as important and diverse as those ... and stress response, antigen presentation, modulation ... channels, cell cycle regulation, transcription, and ...
Biology Products: