Navigation Links
Sperm stem cells closer to being like embryonic stem cells

ne stem cells can also be immortalized in culture. Although genetic modification of human sperm is not one of their goals, the researchers say it may be possible someday to correct genetic defects in humans ?cystic fibrosis, for example ?by identifying and eliminating in culture a man's sperm stem cells that carry the gene.

Dr. Garbers said that a renewable source of cultured sperm stem cells, rat or human, also could be used to test for male-directed contraceptives, and a company is already interested in this possibility.

One of the breakthroughs in this study was developing a new type of medium to grow the cells in, and another was the use of a genetically manipulated "tag" that specifically labeled germ cells with a green fluorescent protein, making the germ cells easier to identify when mixed with other cell types.

"The rat testes contain other cells types in addition to stem cells," Dr. Hamra said. "If these other cells are included in the culture, they produce chemicals that block the ability of the stem cells to remain stem cells. We're still trying to figure out why. But the key is to start with a sample that is 100 percent pure germ cells, which we achieved using the fluorescent marker and other purification methods that are different from those used by other research groups."

Other UT Southwestern researchers involved with the work were Dr. Robert Hammer, professor of biochemistry and in the Green Center, and research technicians Karen Chapman, Derek Nguyen and Ashley Williams-Stephens.


'"/>

Source:UT Southwestern Medical Center


Page: 1 2 3

Related biology news :

1. Sperm trading can resolve hermaphrodite mating conflicts
2. Sperm created in the laboratory from embryonic stem cells produce viable progeny
3. Wisconsin scientists grow critical nerve cells
4. Spleen may be source of versatile stem cells
5. Researchers discover way to make cells in the eye sensitive to light
6. Priming embryonic stem cells to fulfill their promise
7. Lack of enzyme turns fat cells into fat burners
8. Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas
9. Elusive HIV shape change revealed; Key clue to how virus infects cells
10. Mouse brain cells rapidly recover after Alzheimers plaques are cleared
11. Enzyme allows B cells to resist death, leading to leukemia
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Sperm stem cells closer being like embryonic stem cells

(Date:10/18/2014)... with undiagnosed, suspected genetic conditions, a certain type of ... diagnostic yield than traditional molecular diagnostic methods, according to ... is being released to coincide with the American Society ... sequences the protein­coding region of the genome (the complete ... cell or organism), has been rapidly applied in research ...
(Date:10/16/2014)... on the human body. Battles are won, lost ... cancer, this stalemate—known as tumor dormancy—can last up ... phenomena that is poorly understood. , A ... Salvatore Torquato, a Professor of Chemistry at Princeton ... dormancy and the switch to a malignant state. ...
(Date:10/16/2014)... Virus causes severe respiratory tract infections and worldwide ... Scientists at VIB and Ghent University have succeeded ... this common virus infection. , Xavier Saelens ... paves the way for the development of a ... that causes suffering in numerous small children and ...
Breaking Biology News(10 mins):Study examines type of exome sequencing and molecular diagnostic yield 2Study examines type of exome sequencing and molecular diagnostic yield 3Modeling tumor dormancy 2New perspectives for development of an RSV vaccine 2
... of Americans are obese, and these individuals often experience ... cardiovascular problems. In response to the so-called "obesity epidemic," ... health outcomes of obese individuals through diet and exercise. ... certain exercises that benefit obese men may not have ...
... Institute for Biological Studies has received a $42 million ... Center for Genomic Medicine (HCGM), a research center dedicated ... chronic human diseases. The award, from the Leona ... interdisciplinary research that paves the way to new therapies ...
... SAN DIEGO , Jan. 23, 2013 ... discovery and development of innovative treatments for cardiovascular ... and Trademark Office (USPTO) issued a notice of ... claims that cover methods for identifying compounds that ...
Cached Biology News:Women must do more to reap same positive health outcomes as men, MU research suggests 2Salk Institute awarded historic $42 million grant from the Helmsley Charitable Trust 2Salk Institute awarded historic $42 million grant from the Helmsley Charitable Trust 3Celladon Corporation Receives Notice of Allowance from United States Patent and Trademark Office 2Celladon Corporation Receives Notice of Allowance from United States Patent and Trademark Office 3
(Date:10/20/2014)... , Oct. 20, 2014 PureTech ... company tackling big healthcare problems, announced today the ... round, with participation from Invesco Perpetual, a $120 ... used to drive PureTech,s existing pipeline forward and ... "PureTech has the scientific creativity to really go ...
(Date:10/20/2014)... Rochelle, Virginia (PRWEB) October 20, 2014 ... of NDA Partners LLC, announced today that Ellen ... and legal support for the pharmaceutical industry, has ... and manager of its legal services practice. ... reports and expert witness and testimony, to top ...
(Date:10/19/2014)... October 19, 2014 The Latin American ... market in Latin America with analysis and forecast of ... 2013, and is expected to reach $2,366.8 million by ... 2018. , Browse through the TOC of the Latin ... of the in-depth analysis provided. It also provides a ...
(Date:10/19/2014)... 19, 2014 NextCODE Health, which enables clinicians and ... real time, today announced the launch of its new genomic ... at the American Society of Human Genetics (ASHG) annual meeting ... sign up and apply for free beta access, visit ... benefits can be viewed here . The ...
Breaking Biology Technology:PureTech Announces Expansion with Oversubscribed $55M Funding Round 2PureTech Announces Expansion with Oversubscribed $55M Funding Round 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 4PureTech Announces Expansion with Oversubscribed $55M Funding Round 5PureTech Announces Expansion with Oversubscribed $55M Funding Round 6NDA Partners Appoints Ellen Teplitzky, JD as Director of its Legal Services Practice 2The Latin American hardware encryption display market is expected to reach $2,366.8 million by 2018 - New Report by MicroMarket Monitor 2The Latin American hardware encryption display market is expected to reach $2,366.8 million by 2018 - New Report by MicroMarket Monitor 3The NextCODE Exchange: The first global, real-time system for sharing full-resolution genomic data 2The NextCODE Exchange: The first global, real-time system for sharing full-resolution genomic data 3
... Pharmaceuticals, Inc.,(Nasdaq: AMLN ) will be presenting at ... 2008 at 10:00 a.m. PT in Las Vegas. Michael,York, ... providing a corporate overview., The live presentation and ... made available following the event. The webcast and,recording will ...
... Agreement expands Dermagraft presence within government channels, ... May 7 Advanced,BioHealing, Inc. (ABH) and ... on the promotion of Dermagraft(R) within the ... of the agreement,Regenesis will provide its specialized ...
... Demonstrate Abbott,s Most Advanced NNR Candidate ABT-089 ... Adults With ADHD, ABBOTT PARK, Ill., May ... leading scientists will present new Phase II data ... agonist, is a,potentially effective and safe treatment for ...
Cached Biology Technology:Advanced BioHealing and Regenesis Biomedical Form Co-Promotion Alliance for Dermagraft(R) 2Advanced BioHealing and Regenesis Biomedical Form Co-Promotion Alliance for Dermagraft(R) 3Abbott Scientists Present a New Approach for Treating Attention-Deficit Hyperactivity Disorder 2Abbott Scientists Present a New Approach for Treating Attention-Deficit Hyperactivity Disorder 3Abbott Scientists Present a New Approach for Treating Attention-Deficit Hyperactivity Disorder 4Abbott Scientists Present a New Approach for Treating Attention-Deficit Hyperactivity Disorder 5
... Buffer is a convenient, premixed, ... samples and Perfect RNA Markers. ... no dilution and is suitable ... Simply mix equal volumes of ...
... cells were cultured in DMEM and harvested at ... to keep the antigens in their native forms, ... are arrayed on a 12-well (5 mm) adhesive ... to enhance cellular attachment and to minimize background ...
... CopyControl™ vector can be induced prior to ... provide the stability of single-copy BACs with ... other cloning vectors. The kits provide the ... insert size screening system) necessary to create ...
... 3T3 cells were cultured in DMEM with 4 ... of growth. In order to keep the ... in acetone-methanol. The cells are arrayed on ... each wells surface specifically treated to enhance cellular ...
Biology Products: