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Special Imaging Study Shows Failing Hearts Are 'Energy Starved'

heart failure were similarly tested to measure the CK flux. Results showed that CK flux in healthy hearts is adequate to supply energy to the heart over a fairly wide normal range of rest and stress conditions.

However, in patients with mild-to-moderate heart failure, there was a 50 percent reduction in the ATP energy supplied by the CK reaction. “The failing hearts have an energy supply deficit,?says Bottomley. “The reduction is sufficiently large that the supply may be insufficient to match energy demands of the heart during stress or exercise, which is often when symptoms appear. Many factors may contribute to human heart failure, but a failure in the energy supply would certainly affect the heart’s function if supply can’t be met.?/p>
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Source:Johns Hopkins Medicine


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