Navigation Links
Soft-cell approach cuts animal tests

cal industries.

The in vitro method "opens new possibilities for toxicity testing of industrial chemicals, environmental contaminants, workplace airborne contaminants, and fire combustion products", says Dr Hayes.

The technique has several advantages over conventional tests:

  • The use of human cells (as opposed to animal cells) generates data representative of direct human chemical exposure.
  • A number of human cell types such as lung, skin and liver can be used to represent target organs that are more likely to be significantly exposed or affected by air pollutants. As the respiratory system is both a site of toxicity for pulmonary toxicants, and a pathway for inhaled chemicals to reach other organs, relevant airway cells and lung cells are a major focus for inhalation studies.
  • The advantage of using human cell lines and cultures is that the researcher can study toxicity mechanisms at the molecular/cellular level at an earlier stage specifically for individual chemicals, depending on their site of action within the human body without using animals. For example, when assessing the toxicity of formaldehyde, which is known to have a toxic effect on the liver, liver type cells such as hepatocytes can be chosen.
  • The in vitro technique is cheap and portable, so scientists can measure immediate toxicity events, rather than waiting for toxicity to be expressed as organ or organism failure many months or even years down the track from initial exposure.
  • The application of in vitro methods could open new possibilities for toxicity testing of industrial chemicals, occupational and environmental contaminants, combustion products and respiratory therapeutics and lead to a better understanding of the interactions between chemical exposure and toxic effects of single chemicals and chemical mixtures.

'"/>

Source:University of New South Wales


Page: 1 2 3

Related biology news :

1. Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.
2. MSI releases moleculizer - a new approach to simulation of intracellular biochemical networks
3. Stopping smallpox in its tracks: A new anti-viral approach
4. Building a protein name dictionary from full text: a machine learning term extraction approach
5. Rensselaer researchers develop approach that predicts protein separation behavior
6. Huntingtons cure in flies lays groundwork for broader treatment approaches
7. Results of worlds first gene therapy trial for arthritis show approach safe, feasible
8. Vaginal gel may provide a new approach to HIV prevention
9. Clinical trial to test stem cell approach for children with brain injury
10. Study in Science holds promise for a new approach to drug therapy
11. U-M researchers take new approach to defeating Gram-negative bugs
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Soft cell approach cuts animal tests

(Date:6/25/2015)... 25, 2015  Imagine a tool specifically designed to ... happier life. That,s exactly what USANA,s True Health ... cutting-edge, portable health program provides a personalized approached to ... improve your lifestyle and nutrition. At ... Wednesday night, USANA,s THA was honored with the Industry ...
(Date:6/24/2015)... , June 24, 2015 The biologics ... The major drivers for the market include growth of ... of new drug launches. Over the years, the number ... Between 2001 and 2010, the FDA approved 225 drug ... to WIPO, Europe accounted for ...
(Date:6/24/2015)... , June 24, 2015  Synaptics Inc. ... human interface solutions, today announced that Sharp has ... provide secure authentication for its latest flagship smartphone ... more than 200 million shipments of its fingerprint ... reinforces Synaptics, strength, scalability and leadership in the ...
Breaking Biology News(10 mins):@USANAinc's Personalized Nutrition Program Wins Industry Innovation Award 2Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 2Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 3Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 4Synaptics Brings Natural ID Technology to Sharp's Newest Flagship Smartphone 2
... and other genetic techniques led by Adelaide researchers are ... with destroying protected rainforests. DNA fingerprinting for timber ... led by the University of Adelaide that ... forests where they came from. Professor Andrew Lowe, ...
... nicotine receptors are only important to smokers trying to ... in the FASEB Journal ( http://www.fasebj.org ) ... in social interaction and the ability to choose between ... nicotinic receptors in the prefrontal cortex are essential for ...
... the new generation of ExPASy, a web portal which ... bioinformatics resources. Until now, ExPASy was known as a proteomics-dedicated ... this resource was the first website available for the biomedical ... websites as a whole. Eighteen years later, ExPASy is still ...
Cached Biology News:Using DNA in fight against illegal logging 2Your brain on nicotine: Nicotine receptors affect social behavior 2SIB launches next generation ExPASy, an entry portal to indispensable bioinformatics resources 2
(Date:6/30/2015)... , June 30, 2015  The University ... in Biosciences (CCE/Bio) and UC San Diego Extension ... to be held Aug.  12 – 14, 2015, ... This three-day workshop provides an intense exposure to ... biotechnology, and is well-suited to biologists, process engineers ...
(Date:6/30/2015)... - RepliCel Life Sciences Inc. (OTCQB: REPCF) (TSX.V: ... on the development of autologous cell therapies, announced today ... clinical trial of RCT-01, being tested for the ... enrolled and their tissue biopsy sent for processing ... of non-bulbar dermal sheath (NBDS) cells isolated from ...
(Date:6/30/2015)... Edwardsville, IL (PRWEB) , ... June 30, 2015 ... ... resigned effective August 14. She has accepted the position of vice president of ... on August 17. , “I greatly appreciated the opportunity to lead SIUE ...
(Date:6/30/2015)... Tampa, Florida (PRWEB) , ... June 30, 2015 ... ... medical cannabis digital media company, launched “Cannavoices,” an unprecedented digital video and ... the largest but also the most dynamic collection of legal medical cannabis stories ...
Breaking Biology Technology:UC San Diego Extension to Offer Third Annual Microbial Fermentation Workshop 2RepliCel Life Sciences Enrolls First Participant in Phase 1/2 Clinical Trial of RCT-01 for Chronic Achilles Tendinosis 2RepliCel Life Sciences Enrolls First Participant in Phase 1/2 Clinical Trial of RCT-01 for Chronic Achilles Tendinosis 3RepliCel Life Sciences Enrolls First Participant in Phase 1/2 Clinical Trial of RCT-01 for Chronic Achilles Tendinosis 4SIUE’s Furst-Bowe Accepts VP of Instruction at CVTC 2SIUE’s Furst-Bowe Accepts VP of Instruction at CVTC 3Cannavoices Launches a Legal Medical Cannabis Documentary Initiative 2Cannavoices Launches a Legal Medical Cannabis Documentary Initiative 3
... , CRANBURY, N.J., Sept. 3 Palatin Technologies, ... will present at the Rodman & Renshaw 11(th) Annual Global Investment ... The conference is being held at the New York Palace Hotel, ... President and Chief Executive Officer of Palatin Technologies, will provide an ...
... Yeng Ming, 35, a lecturer with the School of Materials ... been awarded one of the three inaugural L,Oral Singapore for ... Lam and the two other women scientists have each won ... of women scientists to the advancement of science and research ...
... COLUMBIA, Md., Sept. 2 ACell, Inc. is announcing ... , , The conference will be held ... Palace Hotel in New York City. James DeFrancesco, Chief Executive Officer ... 11th beginning at 9:10 AM (EDT) in the Hubbard Room. The ...
Cached Biology Technology:NTU professor bags inaugural award honoring women in science 2NTU professor bags inaugural award honoring women in science 3ACell's CEO to Present at Rodman & Renshaw's 2009 Annual Global Investment Conference 2
S-100A10 (H-80)...
Vapor phase risers are available in various heights to accomodate a variety of inventory solutions. Risers are used to creat a false bottom in which the tanks platform rests and Liquid nitrogen is s...
... degrades single-stranded DNA and RNA endonucleolytically ... acids (DNA:DNA, DNA:RNA or RNA:RNA) are ... high concentrations of enzyme (1). The ... termini from double-stranded DNA (2), for ...
SP6 RNA Polymerase, 50 l, 20 U/l ,Cap Scribe Buffer, 100 l, 5x conc....
Biology Products: