Navigation Links
Smokers invite to test vaccine against nicotine addiction

UCSF's Habit Abatement Clinic is testing a vaccine that enlists help from the immune system to keep nicotine away from the brain. The vaccine is designed to help smokers quit and to limit the urge to start smoking again.

Called NicVax, the investigational vaccine is being developed by Nabi Biopharmaceuticals to prevent and treat nicotine addiction and to help people quit smoking. Normally when a smoker inhales, nicotine is carried by the bloodstream to the brain, where it triggers neuro-receptors to generate positive sensations that can lead to addiction. The vaccine stimulates the immune system to produce antibodies that recognize the small nicotine molecule. Bound to these antibodies, nicotine molecules no longer can cross the blood-brain barrier and enter the brain.

"With little or no nicotine reaching the brain, smoking is less rewarding. That gives the smoker a chance to change the behavioral and social factors that also influence smoking," said Victor Reus, MD, principal investigator for the study at UCSF.

Because immune antibodies remain in the body for some time, Reus said it is hoped that the vaccine also will prevent relapse. When a vaccinated smoker lights up months after quitting, the person should not experience the nicotine-triggered reward that tempts most people back into the habit.

Northern California smokers over 18 are invited to join a national study to determine whether NicVax can help people abstain from smoking and help them avoid relapsing within the next 12 months. Participation is free and requires a one-year commitment to come to San Francisco for injections and follow-up visits. The study also includes five behavioral counseling sessions. Participants will be paid for each visit and given validated parking at the clinic.


'"/>

Source:University of California - San Francisco


Page: 1

Related biology news :

1. Brain Scan Study of Smokers Reveals Signature of Craving
2. Smokers quit after damage to brain region
3. Research advances quest for HIV-1 vaccine
4. A much-needed shot in the arm for HIV vaccine development
5. Discovery of key proteins shape could lead to improved bacterial pneumonia vaccine
6. Gene vaccine for Alzheimers disease shows promising results
7. Influenza vaccine uses insect cells to speed development
8. Norovirus, AIDS vaccine and Hepatitis Virus
9. HIV vaccine trial breaks ground for future research
10. Live vaccines more effective against horse herpes virus
11. NIAID begins clinical trial of West Nile virus vaccine
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/21/2016)... 21, 2016   Neurotechnology , a provider ... today announced that the MegaMatcher On Card fingerprint ... for the NIST Minutiae Interoperability Exchange (MINEX) ... mandatory steps of the evaluation protocol. ... test of fingerprint templates used to establish compliance ...
(Date:11/17/2016)... 17, 2016  AIC announces that it has just released a new white paper ... high-performance scale-out plus high speed data transfer storage solutions. Photo - ... ... ... Setting up a high performance computing or HPC ...
(Date:11/15/2016)... Research and Markets has announced the addition of the ... their offering. ... The global bioinformatics market ... 6.21 Billion in 2016, growing at a CAGR of 21.1% during ... is driven by the growing demand for nucleic acid and protein ...
Breaking Biology News(10 mins):
(Date:12/7/2016)... 7, 2016  Vyriad Inc. announced today the appointment ... Board of Directors. "We are delighted to ... business and develop our oncolytic viruses as the next ... Stephen Russell , MD, PhD, CEO of Vyriad. "Al ... vision and passion for making a difference for cancer ...
(Date:12/7/2016)... ... December 07, 2016 , ... ... resource recovery solutions for industrial facilities, today announced that one of the nation’s ... to use Cambrian’s novel water-energy purchase agreement (WEPA). Under the WEPA, a first ...
(Date:12/6/2016)... Texas , Dec. 6, 2016 The ... for its adoption of arnica ( Arnica montana ... support to ABC,s HerbMedPro database, a ... important scientific and clinical research data on the ... popular herbs. Naturopathica, a wellness company ...
(Date:12/6/2016)... (PRWEB) , ... December 06, 2016 , ... ... of custom industrial automation and IT solutions, today announced the company has successfully ... reliably delivered professionally executed automation and control systems integration services to leading companies ...
Breaking Biology Technology: