Navigation Links
Smokers invite to test vaccine against nicotine addiction

UCSF's Habit Abatement Clinic is testing a vaccine that enlists help from the immune system to keep nicotine away from the brain. The vaccine is designed to help smokers quit and to limit the urge to start smoking again.

Called NicVax, the investigational vaccine is being developed by Nabi Biopharmaceuticals to prevent and treat nicotine addiction and to help people quit smoking. Normally when a smoker inhales, nicotine is carried by the bloodstream to the brain, where it triggers neuro-receptors to generate positive sensations that can lead to addiction. The vaccine stimulates the immune system to produce antibodies that recognize the small nicotine molecule. Bound to these antibodies, nicotine molecules no longer can cross the blood-brain barrier and enter the brain.

"With little or no nicotine reaching the brain, smoking is less rewarding. That gives the smoker a chance to change the behavioral and social factors that also influence smoking," said Victor Reus, MD, principal investigator for the study at UCSF.

Because immune antibodies remain in the body for some time, Reus said it is hoped that the vaccine also will prevent relapse. When a vaccinated smoker lights up months after quitting, the person should not experience the nicotine-triggered reward that tempts most people back into the habit.

Northern California smokers over 18 are invited to join a national study to determine whether NicVax can help people abstain from smoking and help them avoid relapsing within the next 12 months. Participation is free and requires a one-year commitment to come to San Francisco for injections and follow-up visits. The study also includes five behavioral counseling sessions. Participants will be paid for each visit and given validated parking at the clinic.


Source:University of California - San Francisco

Page: 1

Related biology news :

1. Brain Scan Study of Smokers Reveals Signature of Craving
2. Smokers quit after damage to brain region
3. Research advances quest for HIV-1 vaccine
4. A much-needed shot in the arm for HIV vaccine development
5. Discovery of key proteins shape could lead to improved bacterial pneumonia vaccine
6. Gene vaccine for Alzheimers disease shows promising results
7. Influenza vaccine uses insect cells to speed development
8. Norovirus, AIDS vaccine and Hepatitis Virus
9. HIV vaccine trial breaks ground for future research
10. Live vaccines more effective against horse herpes virus
11. NIAID begins clinical trial of West Nile virus vaccine
Post Your Comments:

(Date:9/29/2015)... -- iDAvatars is excited to be named one of the first ... official announcement was recently made at an invite-only IBM ... San Francisco , where iDAvatars presented a demo of ... "It is both an honor and a privilege to ... market the cognitive power of IBM Watson in our product, ...
(Date:9/28/2015)... , Sept. 28, 2015 Synaptics Inc. ... interface solutions, today announced that Lenovo has selected Synaptics ... sensor, FS4202, for its latest smartphone, the Vibe P1. ... access to unlock the device and provide swift access ... The feature-rich Natural ID FS4202 sensor solution utilizes ...
(Date:9/10/2015)... Report Details Emerging Biological ... and Revenue Prospects to Help You Stay Ahead ... new drug classes? Get the latest technological and ... market data and industry knowledge, benefitting your influence. ... and sales predictions. Visiongain,s new study reveals ...
Breaking Biology News(10 mins):
(Date:10/12/2015)... Carolina (PRWEB) , ... October 12, 2015 , ... Spirax ... announce the release of the CSM-C 600 compact clean steam generator . ... steam that meets the requirements of HTM2031, HTM2010, and EN285 standards. The CMS-C ...
(Date:10/12/2015)... , 12 de octubre de 2015 ... (D-CA) llegó a un récord en el congreso con ... anual de la International Plasma Awareness Week (IPAW), que ... IPAW está patrocinada por la Plasma Protein Therapeutics ... para: , Aumentar la concienciación mundial ...
(Date:10/12/2015)... , Oct. 12, 2015 VolitionRx Limited ... completed clinical study of its NuQ ® blood-based test ... online issue of Clinical Epigenetics , the official journal ... in collaboration with Lund University, ... , MD, PhD, Professor of Surgery and Vice-Dean, Faculty of ...
(Date:10/10/2015)... -- Le 8 octobre, l,honorable Doris O. Matsui ... Congrès sa déclaration de soutien à la troisième ... plasma (IPAW), qui se tiendra du 11 au ... Protein Therapeutics Association (PPTA) et ses sociétés ... Sensibiliser l,opinion publique mondiale autour du don de ...
Breaking Biology Technology: