Navigation Links
Smokers invite to test vaccine against nicotine addiction

UCSF's Habit Abatement Clinic is testing a vaccine that enlists help from the immune system to keep nicotine away from the brain. The vaccine is designed to help smokers quit and to limit the urge to start smoking again.

Called NicVax, the investigational vaccine is being developed by Nabi Biopharmaceuticals to prevent and treat nicotine addiction and to help people quit smoking. Normally when a smoker inhales, nicotine is carried by the bloodstream to the brain, where it triggers neuro-receptors to generate positive sensations that can lead to addiction. The vaccine stimulates the immune system to produce antibodies that recognize the small nicotine molecule. Bound to these antibodies, nicotine molecules no longer can cross the blood-brain barrier and enter the brain.

"With little or no nicotine reaching the brain, smoking is less rewarding. That gives the smoker a chance to change the behavioral and social factors that also influence smoking," said Victor Reus, MD, principal investigator for the study at UCSF.

Because immune antibodies remain in the body for some time, Reus said it is hoped that the vaccine also will prevent relapse. When a vaccinated smoker lights up months after quitting, the person should not experience the nicotine-triggered reward that tempts most people back into the habit.

Northern California smokers over 18 are invited to join a national study to determine whether NicVax can help people abstain from smoking and help them avoid relapsing within the next 12 months. Participation is free and requires a one-year commitment to come to San Francisco for injections and follow-up visits. The study also includes five behavioral counseling sessions. Participants will be paid for each visit and given validated parking at the clinic.


'"/>

Source:University of California - San Francisco


Page: 1

Related biology news :

1. Brain Scan Study of Smokers Reveals Signature of Craving
2. Smokers quit after damage to brain region
3. Research advances quest for HIV-1 vaccine
4. A much-needed shot in the arm for HIV vaccine development
5. Discovery of key proteins shape could lead to improved bacterial pneumonia vaccine
6. Gene vaccine for Alzheimers disease shows promising results
7. Influenza vaccine uses insect cells to speed development
8. Norovirus, AIDS vaccine and Hepatitis Virus
9. HIV vaccine trial breaks ground for future research
10. Live vaccines more effective against horse herpes virus
11. NIAID begins clinical trial of West Nile virus vaccine
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/12/2017)... NEW YORK , Jan. 12, 2017  New research ... around the office of the future.  1,000 participants were simply ... last three months which we may consider standard issue.  Insights ... office of 2017 were also gathered from futurists and industry ... and Dr. James Canton .  Some ...
(Date:1/6/2017)... 2017  SomaLogic announced today that it has ... by iCarbonX, the China -based ... Digital Health Ecosystem that can define each person,s ... biological, behavioral and psychological data, the Internet and ... SomaLogic will provide proteomics data and applications expertise ...
(Date:12/22/2016)... Dec. 20, 2016  As part of its longstanding mission ... personal genetics company, recently released its latest children,s book, titled ... book focuses on the topics of inheritance and variation of ... (NGSS) taught in elementary school classrooms in the US. ... by illustrator Ariana Killoran , whose previous book with ...
Breaking Biology News(10 mins):
(Date:1/14/2017)... ... January 14, 2017 , ... Seattle-based Phase ... end-to-end genome assemblies to researchers around the globe. Long considered a “holy ... answering a wide range of scientific questions. The announcement was made today ...
(Date:1/13/2017)... Research and Markets has announced the addition of the "Biosimilars ... report to their offering. ... The biosimilars market is expected to reach USD 10.90 ... CAGR of 26.3%. The global biosimilars market is ... such as rising incidence of various diseases, increasing demand for biosimilar ...
(Date:1/13/2017)... (PRWEB) , ... January 13, 2017 , ... ... market products containing an organic compound called fulvic acid that farms, greenhouses and ... operations that grow cannabis are among the fastest growing segments of customers using ...
(Date:1/13/2017)... ... 13, 2017 , ... FireflySci, in response to several customers’ ... solutions for measurements where traditional cuvette applications are not convenient. For instance, a ... sample that would not fit into a typical cuvette inside a spectrophotometer. In ...
Breaking Biology Technology: