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Sex chromosome genes influence aggression andmaternal behavior, say UVa researchers

ces behavior. Gonadal male mice (those with Sry with either the XX or XY sex complement) behaved most aggressively. But females with the Y chromosome were aggressive as well. Females with the XX complement were not aggressive, but in contrast they exhibited high levels of maternal behavior by picking up pups and building nests.

"We know that hormones are important for development of sex differences in brain and behavior," Rissman said. "But this is another component of the sex difference that needs to be examined." In all probability, Rissman said, genes and hormones interact with each other, especially in males, because they have testosterone and the Y chromosome. "It is our hope that these data could lead to the discovery of new genetic bases for aggression and parental behavior in other animals, including humans."


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Source:University of Virginia Health System


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