Navigation Links
Sex chromosome genes influence aggression andmaternal behavior, say UVa researchers

It has been well documented that, across human cultures and in most mammals, males are usually more aggressive and less nurturing than females. It's simple to blame male hormones, like testosterone, for male behavior such as aggression. But maybe it's in our genes, too.

Indeed such social behavior also has a genetic basis, according to new research on mice by neuroscientists at the University of Virginia Health System. "The differences in sex chromosomes, XX versus XY, are also responsible for differences in adult behavior," explained Emilie Rissman, PhD, a professor of biochemistry and molecular genetics at UVa, who studied aggression and maternal behavior in genetically engineered mice. "Sex chromosome genes may not be the whole story that determines how aggressive or motherly we are, but they are a partof it."

Rissman's work is published in the Feb. 22 issue of The Journal of Neuroscience, found online at www.jneurosci.org. Co-authors on the paper are scientists at the University of California Los Angeles and the National Institute for Medical Research in London, England.

Using mouse models, Rissman and the research team uncoupled the testis-determining gene Sry on the male Y chromosome from other sex chromosome genes. The presence of Sry leads to the development of the testes and high levels of androgens in males, which is partly responsible for aggression. Sry was deleted from the Y chromosome and replaced by a transgenic copy.

In their experiments, the researchers compared mice with or without the Sry gene (either males with testes or ovary-bearing females) to mice with the XX versus XY sex chromosomes. They tested how long it took for mice to become aggressive when another mouse was placed in their home territory. The researchers also clocked the time it took to exhibit spontaneous parental behavior by retrieving a pup.

The researchers found that the sex chromosome complement, as well as gonadal sex differences, influen
'"/>

Source:University of Virginia Health System


Page: 1 2

Related biology news :

1. Found: Missing sequence of the human Y chromosome
2. Variation in womens X chromosomes may explain differences among individuals, between sexes
3. Scientists analyze chromosomes 2 and 4
4. Normal chromosome ends elicit a limited DNA damage response
5. Utah researchers confirm chromosome may harbor autism gene
6. Mouse to man: The story of chromosomes
7. Movement of chromosome in nucleus visualized
8. Signature of chromosome instability predicts cancer outcomes
9. Researchers use multiphoton microscopy to watch chromosomes in action
10. Short chromosomes put cancer cells in forced rest
11. Researchers attach genes to minichromosomes in maize
Post Your Comments:
(Date:4/17/2014)... drug under clinical trials to treat tuberculosis could be ... act against various bacteria, fungal infections and parasites, yet ... Illinois chemists and collaborators. , Led by U. of ... different ways the drug SQ109 attacks the tuberculosis bacterium, ... pathogens from yeast to malaria and how targeting ...
(Date:4/17/2014)... Information about archaeological remains of ancient chili peppers in ... words for chili peppers in ancient dialects helped researchers ... value of multi-proxy data analysis. Their results are from ... in a special feature issue of the Proceedings ... and animal domestication edited by Dolores Piperno, staff scientist ...
(Date:4/17/2014)... NJ. April 16, 2014. Kessler Foundation has been ... million from the Department of Defense Spinal Cord ... principal investigator for the randomized, double-blinded, controlled, multi-site ... bone and muscle strength after spinal cord injury. ... & Engineering Research at Kessler Foundation. Two additional ...
Breaking Biology News(10 mins):Multitarget TB drug could treat other diseases, evade resistance 2Chickens to chili peppers 2Chickens to chili peppers 3Kessler Foundation awarded Department of Defense grant for spinal cord injury research 2
... Research and a team of collaborators from across the country ... The paper will be published in Nature Genetics ... disease. The gene, dubbed REL, is a member of the ... the body. The NF-B family seems to have a big ...
... on Sustainable Energy Technologies was chosen for multiple reasons: ... climate change, to provide society with security of energy ... For this a European graduate school is thought ... ,school of thought, to foster the development of excellent ...
... and Australian company Stadvis Pty Ltd have signed a ... accurately predicts glycemic index (GI) and resistant starch (RS) ... industry with an accurate means of testing the functional ... that is much quicker and more cost-effective than the ...
Cached Biology News:Researchers identify new risk factor gene for rheumatoid arthritis 2CSIRO deal to commercialize 'artificial gut' 2
(Date:1/14/2014)... Carahsoft and CDS Federal Services have ... at 2pm EST (11am PST), “Natural Language Processing: Converting ... how technology can turn raw, heterogeneous data into actionable ... The online webinar will last approximately one hour. , ...
(Date:1/14/2014)... Jan. 14, 2014 The largest international professional ... plants and therapeutic derivatives thereof has endorsed an ... researchers about the challenges of adulterated herb and ... The Society for Medicinal Plant ...
(Date:1/14/2014)... Rockville, MD (PRWEB) January 14, 2014 ... dedicated to developing innovative information technology solutions for ... other health care stakeholders, announced today the signing ... the US Food and Drug Administration (FDA). ...
(Date:1/14/2014)... Altadena, CA (PRWEB) January 14, 2014 ... Angeles County), California, and Montreal, Canada, has big ideas ... and non-fiction. The press's goals are to produce high-quality, ... e-books to support local businesses. , The first ...
Breaking Biology Technology:Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information 2Bitingduck Press Looks Forward to 2014 With Multimedia E-books 2
... Million Signed in Fourth Quarter, SUNNYVALE, Calif., Aug. ... leader in the field of radiosurgery,announced today financial results ... 2008., For the fourth quarter of fiscal 2008, ... increase over fourth quarter of fiscal 2007,total revenue of ...
... to better emphasize its customer-centric business approach., ... Inc., a,Chicago-area based process and automation engineering firm ... that the company is changing its,corporate identity to ... of Cascade Solutions, "Throughout,our 14 years of serving ...
... system receives Health Canada clearance to treat severe ... vascular dyschromia and wrinkles, MOUNTAIN VIEW, Calif., Aug. ... and market leader of aesthetic,laser skin treatments, today announced ... the recent Health Canada Clearance. The Canadian,debut of the ...
Cached Biology Technology:Accuray Announces Results for the Fourth Quarter and Fiscal Year End 2008 2Accuray Announces Results for the Fourth Quarter and Fiscal Year End 2008 3Accuray Announces Results for the Fourth Quarter and Fiscal Year End 2008 4Accuray Announces Results for the Fourth Quarter and Fiscal Year End 2008 5Accuray Announces Results for the Fourth Quarter and Fiscal Year End 2008 6Accuray Announces Results for the Fourth Quarter and Fiscal Year End 2008 7Accuray Announces Results for the Fourth Quarter and Fiscal Year End 2008 8Accuray Announces Results for the Fourth Quarter and Fiscal Year End 2008 9Cascade Controls Changes Corporate Identity to Cascade Solutions 2Reliant Technologies Announces Canadian Launch of Fraxel re:pair(R) Laser: A New Class of Treatment Therapy for CO2 Laser Skin Resurfacing 2Reliant Technologies Announces Canadian Launch of Fraxel re:pair(R) Laser: A New Class of Treatment Therapy for CO2 Laser Skin Resurfacing 3Reliant Technologies Announces Canadian Launch of Fraxel re:pair(R) Laser: A New Class of Treatment Therapy for CO2 Laser Skin Resurfacing 4
... RNA Sample Buffer is a ... for experimental samples and Perfect ... buffer needs no dilution and ... denaturing gels. Simply mix equal ...
... Mouse EL-4 cells were cultured in DMEM and ... In order to keep the antigens in their ... The cells are arrayed on a 12-well (5 ... specifically treated to enhance cellular attachment and to ...
... induced prior to DNA purification increasing DNA ... single-copy BACs with the high yields associated ... kits provide the linearized vector and associated ... necessary to create a 10X human BAC ...
... NIH / 3T3 cells were cultured in DMEM ... log phase of growth. In order to ... were fixed in acetone-methanol. The cells are ... slide, with each wells surface specifically treated to ...
Biology Products: