Navigation Links
Serotonin, acting in a specific brain region, promotes sleep in fruit flies

Researchers have found that the neurotransmitter serotonin, known to affect many behaviors, also appears to promote lasting, quality sleep in an animal model for understanding how sleep is regulated. While central to the lives of most animals, the proper regulation sleep remains a largely enigmatic process.

The findings are reported by Quan Yuan, William Joiner, and Amita Sehgal at the University of Pennsylvania, and appear in the June 6th issue of Current Biology.

The fruit fly, Drosophila melanogaster, is now established as a useful model for sleep research. The simple nervous system of the fly enables researchers to ask basic questions about sleep regulation and function that have been difficult to address in the more complicated mammalian systems.

Using the fly model in their new study, the researchers showed that pharmacological treatment with serotonin increases the amount, as well as the quality, of sleep. Serotonin even improves sleep in certain mutant flies that normally sleep less or have fragmented sleep, suggesting that serotonin treatment can overcome some deficits caused by other sleep problems. The researchers also identified a serotonin receptor that affects sleep, and showed that it acts in a specific region of the fly brain known as the mushroom bodies. Interestingly, the mushroom bodies are required for learning and memory in flies. Given that consolidation of memory is one of the functions hypothesized for sleep, and that serotonin is known to be involved in learning and memory in other animals, it is possible that the effect of serotonin on sleep is related to its role in learning and memory.


'"/>

Source:Cell Press


Page: 1

Related biology news :

1. Scientists directly view immune cells interacting to avert autoimmunity
2. Electronic chip, interacting with the brain, modifies pathways for controlling movement
3. Products containing specific probes for detecting alternative splice forms protected
4. Scientists generate patient-specific stem cells, Science study says
5. Identification of specific genes predicts which patients will respond to Hepatitis C treatment
6. Eating, body weight regulated by specific neurons
7. Tool developed to silence genes in specific tissues using RNAi
8. Gene-specific Ebola therapies protect non-human primates from lethal disease
9. Unique dual target specificity of kinase inhibitor key for success against cancer
10. A new male-specific gene in algae unveils an origin of male and female
11. Scientists identify specific enzymes that make meningitis hard to fight
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/15/2016)... DUBLIN , April 15, 2016 ... of the,  "Global Gait Biometrics Market 2016-2020,"  report ... http://photos.prnewswire.com/prnh/20160330/349511LOGO ) , ,The global gait ... CAGR of 13.98% during the period 2016-2020. ... movement angles, which can be used to compute ...
(Date:3/29/2016)... 29, 2016 LegacyXChange, Inc. (OTC: ... and SelectaDNA/CSI Protect are pleased to announce our successful ... a variety of writing instruments, ensuring athletes signatures against ... collectibles from athletes on LegacyXChange will be assured of ... DNA. Bill Bollander , CEO states, ...
(Date:3/18/2016)... 2016 --> --> ... Manned & Unmanned Vehicles, Physical infrastructure and Perimeter Surveillance & ... the border security market and the continuing migration crisis in ... Europe has led visiongain to publish this unique ... --> defence & security companies in the border ...
Breaking Biology News(10 mins):
(Date:5/22/2016)... , ... May 22, 2016 , ... Doctors in Rome ... combating the asbestos cancer, malignant mesothelioma. Surviving Mesothelioma has just posted an article on ... the University of Rome’s Department of Clinical Sciences and Translational Medicine evaluated more than ...
(Date:5/20/2016)... ... May 20, 2016 , ... The recent recall by Costco and Trader ... Safety News on May 12, 2016(1), demonstrates the need for faster and more cost ... biotech firm, PathSensors, Inc. , PathSensor’s latest solution uses a biosensor ...
(Date:5/19/2016)... ... May 19, 2016 , ... KCAS Bioanalytical and Biomarker ... as Director, Large Molecule & Biomarker Bioanalysis. , Dr. Siddiqui has more than ... studies for preclinical and clinical safety programs. “We’ve seen significant demand for, and ...
(Date:5/18/2016)... ... 18, 2016 , ... Shimadzu Scientific Instruments announces its sponsorship ... This two-day camp will take place annually starting June 2016. It will provide ... in preparation for a university academic program. , The laboratory- and technology-focused ...
Breaking Biology Technology: