Navigation Links
Serotonin, acting in a specific brain region, promotes sleep in fruit flies

Researchers have found that the neurotransmitter serotonin, known to affect many behaviors, also appears to promote lasting, quality sleep in an animal model for understanding how sleep is regulated. While central to the lives of most animals, the proper regulation sleep remains a largely enigmatic process.

The findings are reported by Quan Yuan, William Joiner, and Amita Sehgal at the University of Pennsylvania, and appear in the June 6th issue of Current Biology.

The fruit fly, Drosophila melanogaster, is now established as a useful model for sleep research. The simple nervous system of the fly enables researchers to ask basic questions about sleep regulation and function that have been difficult to address in the more complicated mammalian systems.

Using the fly model in their new study, the researchers showed that pharmacological treatment with serotonin increases the amount, as well as the quality, of sleep. Serotonin even improves sleep in certain mutant flies that normally sleep less or have fragmented sleep, suggesting that serotonin treatment can overcome some deficits caused by other sleep problems. The researchers also identified a serotonin receptor that affects sleep, and showed that it acts in a specific region of the fly brain known as the mushroom bodies. Interestingly, the mushroom bodies are required for learning and memory in flies. Given that consolidation of memory is one of the functions hypothesized for sleep, and that serotonin is known to be involved in learning and memory in other animals, it is possible that the effect of serotonin on sleep is related to its role in learning and memory.


'"/>

Source:Cell Press


Page: 1

Related biology news :

1. Scientists directly view immune cells interacting to avert autoimmunity
2. Electronic chip, interacting with the brain, modifies pathways for controlling movement
3. Products containing specific probes for detecting alternative splice forms protected
4. Scientists generate patient-specific stem cells, Science study says
5. Identification of specific genes predicts which patients will respond to Hepatitis C treatment
6. Eating, body weight regulated by specific neurons
7. Tool developed to silence genes in specific tissues using RNAi
8. Gene-specific Ebola therapies protect non-human primates from lethal disease
9. Unique dual target specificity of kinase inhibitor key for success against cancer
10. A new male-specific gene in algae unveils an origin of male and female
11. Scientists identify specific enzymes that make meningitis hard to fight
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Serotonin acting specific brain region promotes sleep fruit flies

(Date:12/17/2014)... , Dec. 15, 2014  HITLAB SM ... Clinical Practices (GCP) audit to confirm its adherence ... regulations. This accomplishment enables HITLAB to conduct regulated ... the highest principles for patient safety and research ... global healthcare access, quality, and delivery with innovative ...
(Date:12/15/2014)... 12, 2014 Research and Markets ... the "Global Facial Recognition Market 2015-2019" ... http://photos.prnewswire.com/prnh/20130307/600769 Facial recognition is ... Facial recognition system measures the overall facial feature ... mouth, and the distance between eyes. Facial recognition ...
(Date:12/11/2014)... , Dec. 10, 2014  Data Sciences ... monitoring, has released a new series of digital ... preclinical toxicology researchers. M series, part of the ... collect the best possible physiologic data when incorporating ... Adding functional endpoints to toxicology studies has evolved ...
Breaking Biology News(10 mins):HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3New telemetry implants expected to change how large animal toxicology studies are conducted 2
... American Academy of Pediatrics National Children,s Art Contest drew hundreds ... With the theme of "My Healthy Lifestyle," the 2011 ... obesity, diet, exercise, sleep and limiting screen time. This was ... of the three age groups each receive a $500 cash ...
... grown apple may hold within it a tiny bit of ... teamed up on a startup that promises to turn slash ... for farmers that helps their soil hold water and nutrients. ... for farmers. "Wine growers, organic farmers and gardeners of all ...
... generally considered to be a good thing for people ... too risky for women who are also pregnant. Some ... the risk of women developing preeclampsia, a condition that ... this might happen has remained unknown. New research using ...
Cached Biology News:Turning slash piles into soil benefit 2Exercise before and during early pregnancy increases two beneficial proteins for mothers-to-be 2
(Date:12/19/2014)... 18, 2014 Egenix, Inc. is pleased to announce ... of the Board, to succeed Donald Fresne ; Mr. ... continue as a member of the Board.  In recognition of ... the company over almost twenty years, the Board designated Mr. ... Directors has established a Search Committee to find a suitable ...
(Date:12/17/2014)... December 17, 2014 Based on ... overall surgical imaging market is dominated by four ... surgical imaging market. These players include GE Healthcare ... Imaging (Germany). , Full Report Copy at ... GE Healthcare can be attributed to its strong ...
(Date:12/17/2014)... (PRWEB) December 17, 2014 Once more, ... provide a larger packaged waste water treatment plant to ... Abdullah Economic City (KAEC). Two years ago Bioshaft successfully ... Gate Development, serving two residential towers with an occupancy ... over a quarter million gallons per day and was ...
(Date:12/17/2014)... Audacity, a leading California-based health and ... the Huntsworth Health Group, is proud to announce the ... her role, Gonzales will serve as Senior Vice President ... to welcome a talent of Jamie’s caliber to the ... “She is a proven healthcare innovation leader and brand ...
Breaking Biology Technology:Global Refurbished Surgical Imaging Market by Product & Application is Estimated to Reach $1.25 Billion by 2019 - New Research Report by MarketsandMarkets 2Global Refurbished Surgical Imaging Market by Product & Application is Estimated to Reach $1.25 Billion by 2019 - New Research Report by MarketsandMarkets 3Global Refurbished Surgical Imaging Market by Product & Application is Estimated to Reach $1.25 Billion by 2019 - New Research Report by MarketsandMarkets 4Audacity Welcomes Healthcare Communications Expert Jamie Gonzales as Senior Vice President of Client Services 2
... 13 Beckman Coulter, Inc. (NYSE: BEC ... that simplify, automate and innovate complex biomedical testing, announced ... October 27, 2010, at 5:00 p.m. ET to discuss ... to the conference call, there will be a webcast ...
... Rice University research that capitalizes on the wide-ranging capabilities ... far more compact and versatile than what is now ... on graphene -- the one-atom-thick form of carbon that ... become key components in future electronic circuits. The discovery ...
... 14, 2010 ... ... --> ... // Results are keyed by longUrl, so we need to grab the first one. for (var r in data.results) ...
Cached Biology Technology:Beckman Coulter to host Conference Call and Webcast Presentation for Third Quarter 2010 Earnings Results on October 27, 2010 2Triple-mode transistors show potential 2550 People Across Europe Will Die Today From a Preventable Lung Disease 2550 People Across Europe Will Die Today From a Preventable Lung Disease 3550 People Across Europe Will Die Today From a Preventable Lung Disease 4550 People Across Europe Will Die Today From a Preventable Lung Disease 5550 People Across Europe Will Die Today From a Preventable Lung Disease 6550 People Across Europe Will Die Today From a Preventable Lung Disease 7550 People Across Europe Will Die Today From a Preventable Lung Disease 8550 People Across Europe Will Die Today From a Preventable Lung Disease 9
Mouse HAI-1 Ectodomain MAb (Clone 199732)...
... Recognizes K+ Cl- Cotransporter-1 ... no significant sequence homology ... CCC.,SPECIES REACTIVITIES: The immunogen ... in human, mouse, porcine ...
IEX-1 S/L (H-20)...
Mouse monoclonal [1.T.4] to WAVE 1 ( Abpromise for all tested applications). Antigen: His6 fusion protein corresponding to full-length rat WAVE1. Entrez Gene ID: 8936...
Biology Products: