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Sensors, a smart dose of medicine for cancer treatment

roprocessor technologies, and its function is to communicate with, and retrieve data from, the sensor arrays. The PC and software provide system control, connectivity to other parts of an overall radiotherapy system, such as record and verify packages, and patient-specific data storage.

INVORAD also developed a cylindrical 'body phantom'. The 'phantom' is given the prescribed dose and the diode sensors pick up the dose actually delivered. "The two modular 2D diode arrays are placed in orthogonal positions inside the phantom, so we have data in 3D over time," says Jaksic.

If the 'phantom' treatment matches the prescription of the simulator, the patient is given treatment. If not, the treatment plan needs to be corrected. "We created modifications on the diodes and diode arrays, improving their specifications for this project. In fact, every element of the project we worked on received some sort of improvement on current systems," says Jaksic.

Some types of MOSFETs can also detect radiation. In the INVORAD MOSFET-based system these are used in-vivo, mounted in medical catheters in the form of linear arrays, entering the patient through a cavity.

"We're currently testing that device in patients with our clinical partner, the Clatterbridge Centre for Oncology, one of the largest oncology centres in the UK. Of the two devices, the diode system is the most commercially viable. However, the MOSFET system is working and we'll have the results of patients trials in the next few months," says Jaksic.

"We need to further optimise some parameters of the diode sensor system, but from the work we've done so far we know how to solve these remaining issues." Jaksic believes it is worth the wait. "Unlike most projects, this device will go straight to market and our commercial partner, ScandiDos in Uppsala, Sweden, is a start-up created for the manufacture and marketing of the device."

Jaksic is particularly pleased because the new sens
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Source:IST Results


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