Navigation Links
Self-assembled DNA buckyballs for drug delivery

ther, the three strands will bind to each other over the complementary portions, creating a Y-shaped molecule. By joining several Y's in the same way, Luo's research group created molecules with several arms, a sort of tree shape (dendri- means tree in Greek). Then they attached polystyrene molecules to the dendrimerlike DNA forming a hybrid molecule called an amphiphile -- a molecule that both likes and hates water. DNA is hydrophillic -- attracted to water -- while polystyrene is hydrophobic -- water repels it.

The researchers expected the amphiphiles to assemble in water into some sort of solid structure arranged so that DNA would have a maximum interaction with water and polystyrene would avoid water as much as possible. Other researchers have used other amphiphiles to make spheres, rods and other solids. The hollow buckyballs were an intriguing and serendipitous surprise. A model suggests that one buckyball consists of about 19,000 amphiphiles, with their water-loving DNA mostly on the outside of the rods that form the structure. How these tens of thousands of molecules were able to self-organize to form such an intricate and complex structure is still an open question, the researchers say. They are seeking collaborators to solve the puzzle.

Luo and Ph.D. graduate students Soong Ho Um, Sang Yeon Kwon and Jong Bum Lee described DNA buckyballs in an invited talk titled "Self-assembly of nanobuckyballs from dendrimer-like-DNA-polystyrene amphiphiles" Sunday, Aug. 28, at the 2005 annual meeting of the American Chemical Society in Washington, D.C. They reminded the audience that although the geometry of solid truncated icosahedrons was first described by Archimedes on paper more than 2,000 years ago, the skeletal, hollow-faced version of buckyballs had not been envisioned until Leonardo da Vinci's illustrations in 1494.

Luo added that DNA buckyballs may turn out to have unusual electronic, photonic and mechanical properties, and that becau
'"/>

Source:Cornell University News Service


Page: 1 2 3

Related biology news :

1. Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin
2. New self-exploding microcapsules could take sting out of drug delivery
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Self assembled DNA buckyballs for drug delivery

(Date:11/7/2014)... , November 6, 2014 Leading ... for better mobile security revolutionizing online transactions.  Companies in focus ... Holdings Ltd. (NYSE: BABA ), Google Inc. (NASDAQ: ... ), eBay Inc. (NASDAQ: EBAY ) and MasterCard ... NXTD and NXTDW), a biometric authentication company focused on ...
(Date:11/5/2014)... biology in the UTSA College of Sciences, is ... to receive a two-year $300,00 National Science Foundation ... The funding supports President Obama,s BRAIN Initiative, a ... technology that will demystify complex brain processes. ... are broken into the interactions of multiple components, ...
(Date:11/4/2014)... PA) – Temple University School of Medicine announced ... winner, an initiative funded by the Bill & ... Professor of Obstetrics, Gynecology and Reproductive Sciences; and ... Temple University School of Medicine will pursue an ... "Maternal Blood Biomarkers to Assess Fetal Neurodevelopment.", Grand ...
Breaking Biology News(10 mins):Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 3Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 4Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 5Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 6UTSA biology professor awarded $300,000 NSF grant for brain research 2UTSA biology professor awarded $300,000 NSF grant for brain research 3Temple University School of Medicine receives Grand Challenges Explorations grant 2
... of burning fossil fuels, running factories and driving cars, ... maple trees growing in the Northeast, according to a ... The sugar maple is the most economically valuable tree ... high-priced lumber, syrup and tourist-attracting fall colors. ...
... burning fossil fuels, running factories and driving cars, has ... trees growing in the Northeast, according to a new ... sugar maple is the most economically valuable tree species ... lumber, syrup and tourist-attracting fall colors. , ...
... or smell, receptors unique to each nerve cell detect the ... process the message to understand what we are smelling or ... it must use many different receptors to sense and interpret ... environments changes in molecular concentrations as small as 0.1 percent, ...
Cached Biology News:Gene therapy prevents the onset of diabetic symptoms in mice 2Gene therapy prevents the onset of diabetic symptoms in mice 3Acid rain causing decline in sugar maples, say researchers 2Acid rain causing decline in sugar maples, say researchers 3Researchers discover how bacteria sense their environments 2
(Date:11/26/2014)... Continuing its award-winning streak, Nerium International, the ... Awards for outstanding creative achievement by its marketing and ... the organization’s top honor, in the Branding category for ... April of this year. The event showcased top speakers ... was awarded a Gold MarCom Award in the Special ...
(Date:11/26/2014)... 25, 2014 Global biostimulants market ... growing at an estimated CAGR of 12.5%. In ... food products with least ecological impacts, farmers are ... to boost crop yield more effectively & efficiently. ... can improve the return on investments. , Leading ...
(Date:11/26/2014)... MA (PRWEB) November 26, 2014 ... collaboration company is proud to announce that Darren Suders ... and Sales. Darren will drive the partner ... positive customer experience. , Darren brings more ... has held key roles in channel operations, from policy ...
(Date:11/26/2014)... Dallas, Texas (PRWEB) November 26, 2014 ... Acid Industry is an in-depth research report on ... analysis, the report introduces Palmitic Acid, basic information, ... overview, policy analysis, and news analysis, etc. ... report analyzes Palmitic Acid market in ...
Breaking Biology Technology:Nerium International™ Wins One Platinum, Two Gold MarCom Awards 22019 Biostimulants Market to Grow at a CAGR of 12.5% Says a New Research Report Available at RnRMarketResearch.com 22019 Biostimulants Market to Grow at a CAGR of 12.5% Says a New Research Report Available at RnRMarketResearch.com 32019 Biostimulants Market to Grow at a CAGR of 12.5% Says a New Research Report Available at RnRMarketResearch.com 4SoundConnect Appoints Director of Channel Development & Sales 2Palmitic Acid Industry Global 2014 Analysis & 2020 Forecasts on Market data, Statics, Development Now at ReportsnReports.com 2Palmitic Acid Industry Global 2014 Analysis & 2020 Forecasts on Market data, Statics, Development Now at ReportsnReports.com 3
... /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. (TSX:,ONC, NASDAQ: ONCY) ... research group at The Institute of Cancer Research, ... combination treatment schedules,of reovirus and radiation in human ... The paper, entitled "Enhanced In vitro and In ...
... environment and holding it indefinitely in molecular-sized containers has been ... say it represents a novel method of gas storage that ... safely and efficiently. , This is a proof of concept ... just improving on a method that already exists, said U ...
... the economy is not,only heading towards a recession but ... during January. However, biotech held steady,with the Burrill Biotech ... posted a January loss of 9.9%, and the Dow, ... ride out extremely volatile capital,markets with less damage because ...
Cached Biology Technology:Oncolytics Biotech Inc. Announces Publication of Research on Combination Reovirus and Radiation Therapy 2Rounding up gases, nano-style 2January Market Jitters Fails to Derail Biotech 2January Market Jitters Fails to Derail Biotech 3January Market Jitters Fails to Derail Biotech 4
Anti-NeuroD 6 Immunogen: Synthetic peptide. Available Date: 36708...
HOXC11 Antibody...
Anti-MMP-14, catalytic domain, clone LEM-2/15.8 Immunogen: Synthetic peptide: amino acid sequence 218-233 within the catalytic domain Available Date: 38579...
Rabbit anti MMP-13, Hinge Region MMP-13 Hinge Region...
Biology Products: