Navigation Links
Secret of worm's poison pill box protein could produce new natural insecticide

Researchers at the University of Warwick have discovered how a protein from a bacterium acts like a cunningly designed poison pill box that could now be used as a basis of a new range of natural insecticides. It had been known that nematode worms can infect and kill insect pests with the help of a bacterium which they harbour inside their intestine.

The bacterium uses a protein (XptA1) a toxin which helps the nematode to kill and feed on the dead body of the insect. The toxin not only kills the target insect but prevents other predators from eating the body giving free reign to the nematode worms to consume it, multiply and move on. However, until now, researchers had little idea of the make up of XptA1 and thus how it worked. The research team, based at the University of Warwick’s horticultural research arm Warwick HRI, have now been able to reveal the shape of the protein XptA1 and discovered a number of properties that make it a particularly efficient natural insecticide and possible alternative to some commercial insecticides that are facing increased resistance in the insect populations they target.

The researchers at Warwick HRI, together with a team of colleagues with expertise in the Structural Biology group in Biological Sciences and in Chemistry at The University of Warwick, as well as Coventry and Nottingham Universities, found that the protein was formed from four sub units in the shape of a hollow cage or box which is configured to bind well to part of a caterpillar’s gut called "Brush Border Membrane Vesicles" (BBMV).

The XptA1 protein seemed to specifically target the BBMV of caterpillars Pieris Brassicae ?(The cabbage white butterfly caterpillar which are pests for many growers). The hollow box structure appears to be a key element of the protein’s design. The hollow shape allows the protein to act as a receptacle for two other proteins (in the case of XptA1 these are XptB1 and XptC1). This forms a poison "c
'"/>

Source:University of Warwick


Page: 1 2

Related biology news :

1. Needling Chromosomes Reveals Cell Division Secret
2. Weill Cornell Research Reveals Secrets Of Trafficking Within Cells
3. Protein Discovery Could Unlock The Secret To Better TB Treatment
4. Secret of smallpoxs success may lead to bioterror cure
5. Secrets to antibodys success against West Nile Virus surprise scientists
6. Secrets of the deep may hold key to life on other planets
7. Secret sex life of killer fungus?
8. Study Unlocks Insects?Secret for Love in the Dark
9. Secrets of the sea yield stronger artificial bone
10. Tiny roundworms telomeres help scientists to tease apart different types of aging
11. Giant deep-sea tubeworms meal ticket comes in as a skin infection
Post Your Comments:
(Date:7/7/2015)... , June 30, 2015 ... announced the addition of the "Capacitive Fingerprint ... To this date, fingerprint sensing technology ... and fingerprint sensors are well developed. This patent ... technology. The domain of capacitive fingerprint ...
(Date:7/2/2015)... 25, 2015 Research and ... "Next Generation Biometrics Market by Application, Technology, Function ... to their offering. The next generation biometrics ... at a CAGR of 17.9% between 2015 and 2020 ... for the market. Safran SA ( ...
(Date:6/29/2015)... , June 24, 2015 ... addition of the "Latin America Biomedical Sensors Market ... their offering. The Latin America Biomedical Sensors ... a CAGR of 2.04% over the period 2014-2020 ... are adaptable to the genetic formulation of each individual. ...
Breaking Biology News(10 mins):Worldwide Capacitive Fingerprint Sensors Patent Landscape Market Report 2015-2020 - Main IP Holders include Seiko Epson, AuthenTec, Sony and STMicroelectronics 2Next Generation Biometrics Market 2015 - Global Forecast to 2020 with Safran, NEC, 3M Cogent, Fujitsu & Suprema Dominating the $24 Billion Market 2Next Generation Biometrics Market 2015 - Global Forecast to 2020 with Safran, NEC, 3M Cogent, Fujitsu & Suprema Dominating the $24 Billion Market 3Latin America Biomedical Sensors Market Report 2015-2020 2
... puts her cubs on the road to success before ... certain hormones that make her budding young leaders more ... the April 27 issue of Nature, is the first ... female's social rank and her ability to influence her ...
... Enzymes that can harm the brain immediately after a stroke ... Insights from the study could change the way stroke is ... of hours to a couple of weeks. The results may ... rats, a team from the Harvard Medical School Departments of ...
... review highlights strong results from a single study at the ... drug Bactrim to help HIV-infected children in poor countries. , ... Bactrim -- one of several brand names for the generic ... that can be deadly to a person whose immune system ...
Cached Biology News:'Bad' enzymes may wear white hats after stroke 2'Bad' enzymes may wear white hats after stroke 3'Bad' enzymes may wear white hats after stroke 4Low-cost drug gaining favor for use in HIV-infected children in poor countries 2
(Date:7/30/2015)... ... July 31, 2015 , ... Ralco is honored to announce that ... County Fair to be held August 5-9 in Marshall. The Ralco Enrichment Center is ... from and how agriculture impacts their daily lives. This unique exhibit also features a ...
(Date:7/30/2015)... ... July 30, 2015 , ... Tronics, a designer ... & Marketing Director. , With more than 25 years of experience in ... Tronics’ business development activities worldwide. He brings to the company his strong expertise ...
(Date:7/30/2015)... Diego , CA (PRWEB) , ... July 30, ... ... announced the successful completion of a field clinical study of its canine osteoarthritis ... developed together with Aratana Therapeutics (Kansas City, KS) and will be marketed in ...
(Date:7/30/2015)... ISN improves the efficiency and effectiveness of contractor management systems. ISN,s online contractor management platform, ... 80 countries. ... ... Over 60,000 Worldwide Customers In More Than 80 Countries ... Dallas, TX , ISN has additional offices in Calgary , ...
Breaking Biology Technology:Ralco Announces Primary Sponsorship of Ralco Enrichment Center at Lyon County Fair 2Tronics appoints Francois Vieillard as Sales and Marketing Director 2VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 2VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 3ISN Reaches Over 60,000 Worldwide Customers 2ISN Reaches Over 60,000 Worldwide Customers 3
... N.Y., July 15 Nikon Instruments Inc.,( http://www.nikoninstruments.com/ ... a very small size with high,performance at a ... These,microscopes allow observation of a wide range of ... applications., The SMZ-445, with 0.8x to 3.5x ...
... on Benefits of Group Purchasing Organizations Hosted,by Trane ... The American Society of,Healthcare Engineering (ASHE) offers professional ... annual conference is no exception. Added,to the roster ... global supplier of,indoor comfort systems and comprehensive facility ...
... Pharmasset, Inc.,(Nasdaq: VRUS ) announced today ... 14, 2008 with a select group of institutional,investors ... in a "registered,direct" offering. The investors have agreed ... $17.85 per share resulting in gross proceeds of,approximately ...
Cached Biology Technology:Nikon Instruments Introduces New Microscopes and Illumination Stand for Education and OEM Markets 2Healthcare Facility Managers Learn to Optimize Surgical Suites at 2008 ASHE Annual Conference 2Healthcare Facility Managers Learn to Optimize Surgical Suites at 2008 ASHE Annual Conference 3Pharmasset Announces $25.9 Million Registered Direct Offering of Common Stock 2Pharmasset Announces $25.9 Million Registered Direct Offering of Common Stock 3
Transcription factor Sp2. [Source:Uniprot/SWISSPROT;Acc:Q02086] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
Rabbit Anti-melatonin (different linkage) Polyclonal Antibody...
... Rabbit monoclonal [EP282Y] to Asparagine ... all tested applications). ... corresponding to residues in the ... Entrez GeneID: ...
Rabbit Anti-melatonin (different linkage) Polyclonal Antibody...
Biology Products: