Navigation Links
Sea urchin genome suprisingly similar to man and may hold key to cures

he sea urchin’s immune system works. The human immune system has two components: innate immunity, with which we are born, and acquired immunity, which is the ability to produce antibodies in response to an infection. Sea urchins only have innate immunity, and it is greatly expanded with 10 to 20 times as many genes as in human.

"Considering that sea urchins have a long life span -- some can live up to 100 years -- their immune system must be powerful," Calestani said. "Sea urchins could very well provide a new set of antibiotic and antiviral compounds to fight various infectious diseases."

The sea urchin has been used for many years as a research model to study embryonic development.

Cell development is very complicated. In order to properly regulate just one gene expression of a single-cell layered gut of the sea urchin larva, at least 14 proteins binding the DNA at 50 sites are needed, Calestani said.

"Multiply that hundreds of times and you begin to understand the level of complexity involved in human development," she added.

Using a "simple" creature like the sea urchin embryo to uncover the molecular basis underlying development offers several experimental advantages compared to the use of mice. Raising sea urchin embryos is easy and inexpensive. One female can provide up to 20 millions eggs. The embryos develop in just three days and are transparent. Also, single cells can be easily observed live in the embryos.

"If we know how these biological processes work, then we can begin to figure out how to intercede to repair and to heal," Calestani said. "It holds a lot of promise."

Calestani is continuing her work with sea urchins at UCF in Orlando by examining the development of pigment cells found in the marine creatures. Those cells also might provide some insight into human immunity to diseases.

Calestani, who teaches genetics at UCF, worked with Davidson at Caltech before arriving
'"/>

Source:University of Central Florida


Page: 1 2 3

Related biology news :

1. Man and mouse share genome structures
2. Whole genome fine map of rice completed
3. Study finds more than one-third of human genome regulated by RNA
4. A bacterial genome reveals new targets to combat infectious disease
5. Scientists decipher genome of fungus that can cause life-threatening infections
6. Highly adaptable genome in gut bacterium key to intestinal health
7. Fleshing out the genome
8. Agilent Technologies new genome analysis technology set to accelerate Australia fight against mesothelioma
9. wFleaBase: the Daphnia genome database
10. NHGRI targets 12 more organisms for genome sequencing
11. Chimp genome reveals a retroviral invasion
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Sea urchin genome suprisingly similar man and may hold key cures

(Date:8/29/2014)... of connections in transcription factor networks (TFNs) to evaluate ... published in PLOS Computational Biology in August. ... to a network,s resilience against mutations. , "In ... TFN models has a greater effect on robustness than ... said Dov A. Pechenick, PhD, lead author and former ...
(Date:8/29/2014)... cell,s nucleus, chromosomal DNA is tightly bound to ... call chromatin. Until about two decades ago, histones ... packing material around which the glamorous DNA strands ... greater appreciation for how DNA/histone interactions govern gene ... institutions studying the sequence of the genome from ...
(Date:8/28/2014)... to announce the selection of Dr. Fred Baxendale as ... those who have served ESA for at least 20 ... Society that has reached an extraordinary level. Candidates for ... and then voted on by the ESA membership. Dr. ... Entomology 2014, ESA,s Annual Meeting in Portland, Oregon this ...
Breaking Biology News(10 mins):Assortativity signatures of transcription factor networks contribute to robustness 2'K-to-M' histone mutations: How repressing the repressors may drive tissue-specific cancers 2'K-to-M' histone mutations: How repressing the repressors may drive tissue-specific cancers 3Fred Baxendale selected as Honorary Member of the Entomological Society of America 2
... peas to show that one copy of a gene (allele) is ... the progeny, the inherited genes are expressed at the right time ... that although gene products could be modified during the life of ... Now it appears that one copy of some genes ...
... Law Enforcement Departments, TAMPA, Fla., June 10 ... leader in electro-stun technology, today,announced that it is ... brand stun products an opportunity to trade their,weapons ... exchange,for price concessions., Ron Bellistri, Stinger,s CEO, ...
... databases of ocean organisms have demoted to alias ... 34 regional and highly specialized inventories. The ... ) contains about 122,500 validated marine species names ... aliases 32% of all names reviewed). ...
Cached Biology News:Genome communication 2Genome communication 3Genome communication 4Stinger Systems To Offer Taser Trade-In Program 2Census of Marine Life lists 122,500 known species, over halfway to complete inventory by Oct. 2010 2Census of Marine Life lists 122,500 known species, over halfway to complete inventory by Oct. 2010 3Census of Marine Life lists 122,500 known species, over halfway to complete inventory by Oct. 2010 4Census of Marine Life lists 122,500 known species, over halfway to complete inventory by Oct. 2010 5
(Date:8/28/2014)... Best Sanitizers, Inc., a leader in hand ... is asking industry professionals to prepare for fall harvest ... soap they’re currently using to the Best Sanitizers’ ... hygiene is critical to fighting cross-contamination and the spread ... criteria are identified to evaluate the effectiveness of an ...
(Date:8/28/2014)... WEST LAFAYETTE, Ind. A new research ... "nanomechanical" properties of tiny structures undergoing stress ... insights to improve designs for microelectronics and ... spectroscopy, reveals information about how heating and ... their mechanical properties. Researchers have discussed the ...
(Date:8/28/2014)... 2014 The ability for organizations to ... will allow individuals to perform at the highest of ... employers looking to compete in this post–recession era. ... trend, as the sector increasingly focuses on the importance ... will have real results on the organization's development and ...
(Date:8/28/2014)... Sterlitech is proud to announce that it ... stable of products . These additional products increase ... membrane filters with surface charges. , “We ... our membrane process testing equipment, and correspondingly, a wider ... explains Sterlitech President Mark Spatz. “The addition of ...
Breaking Biology Technology:Best Sanitizers, Inc. Asks Food Industry Professionals: With Fall Harvest On the Way, Is Your E2 Hand Soap Up to the Task? 2New analytical technology reveals 'nanomechanical' surface traits 2New analytical technology reveals 'nanomechanical' surface traits 3Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 2Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 3Sterlitech Corporation Enhances Its Selection of Flat Sheet Membrane Filters 2
... secretary of the U.S. Department of Health and Human ... , ,Alfacell develops cancer theraputics and is moving closer ... Food and Drug Administration for its lead drug candidate. ... it has a local presence. , ,"I first became ...
... being San Francisco, which kicks of the JP Morgan Annual ... from Sunday and early Monday that the Johnson & Johnson ... longer a done deal. , ,On Sunday, Boston Scientific stepped ... $25 billion (about $3 billion sweeter than Johnson & Johnsons) ...
... governor who delivers a State of the State speech that ... aspiring ex-governor. , ,Whether Republican or Democrat, riding high ... always use their annual State of the State speech to ... voters. Gov. Jim Doyles fourth report to the state was ...
Cached Biology Technology:Health-care eyes focus on San Francisco, war of the stents 2Health-care eyes focus on San Francisco, war of the stents 3Health-care eyes focus on San Francisco, war of the stents 4How's the State of the State? It depends on what numbers are crunched 2How's the State of the State? It depends on what numbers are crunched 3
Leptin Receptor Polyclonal Ab 100 ug purified rabbit anti-mouse Leptin Receptor. Tested in Western blotting....
... of 2D polyacrylamide gel electrophoresis (2D-PAGE) with ... a core technology platform for proteomic analysis. ... complex samples limited only in the dynamic ... large proteins. Quantitative image based analysis of ...
... compact, highly versatile power supply. Capable of producing ... power supply is ideal for PAGE, SDS-PAGE, DNA ... types of small format transfer apparatus. It is ... current with a continuously variable output in either ...
... gel electrophoresis (2D-PAGE) with biological mass spectrometry ... platform for proteomic analysis. 2D-PAGE gels offer ... only in the dynamic range and ability ... image based analysis of separated proteins has ...
Biology Products: