Navigation Links
Sea urchin genome suprisingly similar to man and may hold key to cures

he sea urchin’s immune system works. The human immune system has two components: innate immunity, with which we are born, and acquired immunity, which is the ability to produce antibodies in response to an infection. Sea urchins only have innate immunity, and it is greatly expanded with 10 to 20 times as many genes as in human.

"Considering that sea urchins have a long life span -- some can live up to 100 years -- their immune system must be powerful," Calestani said. "Sea urchins could very well provide a new set of antibiotic and antiviral compounds to fight various infectious diseases."

The sea urchin has been used for many years as a research model to study embryonic development.

Cell development is very complicated. In order to properly regulate just one gene expression of a single-cell layered gut of the sea urchin larva, at least 14 proteins binding the DNA at 50 sites are needed, Calestani said.

"Multiply that hundreds of times and you begin to understand the level of complexity involved in human development," she added.

Using a "simple" creature like the sea urchin embryo to uncover the molecular basis underlying development offers several experimental advantages compared to the use of mice. Raising sea urchin embryos is easy and inexpensive. One female can provide up to 20 millions eggs. The embryos develop in just three days and are transparent. Also, single cells can be easily observed live in the embryos.

"If we know how these biological processes work, then we can begin to figure out how to intercede to repair and to heal," Calestani said. "It holds a lot of promise."

Calestani is continuing her work with sea urchins at UCF in Orlando by examining the development of pigment cells found in the marine creatures. Those cells also might provide some insight into human immunity to diseases.

Calestani, who teaches genetics at UCF, worked with Davidson at Caltech before arriving
'"/>

Source:University of Central Florida


Page: 1 2 3

Related biology news :

1. Man and mouse share genome structures
2. Whole genome fine map of rice completed
3. Study finds more than one-third of human genome regulated by RNA
4. A bacterial genome reveals new targets to combat infectious disease
5. Scientists decipher genome of fungus that can cause life-threatening infections
6. Highly adaptable genome in gut bacterium key to intestinal health
7. Fleshing out the genome
8. Agilent Technologies new genome analysis technology set to accelerate Australia fight against mesothelioma
9. wFleaBase: the Daphnia genome database
10. NHGRI targets 12 more organisms for genome sequencing
11. Chimp genome reveals a retroviral invasion
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Sea urchin genome suprisingly similar man and may hold key cures

(Date:9/18/2014)... protective tentacles of host anemones, but new research shows ... across the open ocean. Although the process of long-distance ... the first time that the high level exchange of ... Steve Simpson, Senior Lecturer in Marine Biology and Global ... the Australian Research Council Centre of Excellence for Coral ...
(Date:9/17/2014)... UCLA atmospheric scientists were instrumental in the creation of ... tool to classify the fire threat potential of the ... a spark into an inferno. The index was introduced ... with UCLA and San Diego Gas and Electric. , ... to "extreme" that will be used to help fire ...
(Date:9/17/2014)... and his doctoral student have designed a device based ... from fog and dew., The device could provide water ... the globe., Cheng Luo, professor in the Mechanical & ... the same College of Engineering department, published "Bioinspired Plate-Based ... (American Chemical Society) Applied Materials & Interfaces ...
Breaking Biology News(10 mins):Expedition finds Nemo can travel great distances to connect populations 2Expedition finds Nemo can travel great distances to connect populations 3UCLA scientists play key role in developing new Santa Ana Wildfire Threat Index 2Shorebird's beak inspires UT Arlington research on water collection 2
... of private health insurance and its consequent lack of ... with uterine cancer and may partly explain the mortality ... data presented at the Third AACR Conference on The ... twice as likely to die within four years compared ...
... The convergence in the coming year of three cyclical conditions ... challenges for states that depend on water from the Colorado ... I were concocting a recipe for a perfect drought, this ... and director of UCLA,s Institute of the Environment and Sustainability. ...
... Oct. 1 For the past three decades, saturated fat has ... a result dietary advice persists in recommending reduced consumption of this ... only a very limited impact on CVD risk -- causing many ... A series of research articles published in the October issue of ...
Cached Biology News:Lack of private health insurance impacted cancer survival 2Ocean conditions likely to reduce Colorado River flows during this winter's drought 2Ocean conditions likely to reduce Colorado River flows during this winter's drought 3Ocean conditions likely to reduce Colorado River flows during this winter's drought 4Think saturated fat contributes to heart disease? Think again 2Think saturated fat contributes to heart disease? Think again 3
(Date:9/18/2014)... -- Research and Markets has announced the ... 2014" report to their offering. ... professional and in-depth study on the current state of ... provides a basic overview of the industry including definitions, ... market analysis is provided for the international markets including ...
(Date:9/18/2014)... , Sept. 18, 2014  U.S. biotech company ... an exclusive license for technology developed by the ... expression in plants, including for applications in production of ... The technology was developed under the direction of ... Kultevat and former president of the Danforth Plant Science ...
(Date:9/18/2014)... , Sept. 18, 2014 /PRNewswire/ - Oncothyreon Inc. (NASDAQ: ... previously announced concurrent but separate underwritten offerings of 10,000,000 ... the public of $2.00 per share, for expected gross ... Series A Convertible Preferred Stock at a price to ... proceeds of $20 million. Each share of Series A ...
(Date:9/18/2014)... (PRWEB) September 18, 2014 OMICS ... the globe to participate in the ‘Open Access ... articles to OMICS Group Pharma Journals ... one of the fastest emerging Sciences, accelerating with ... healthcare services across the globe. The industry is ...
Breaking Biology Technology:Global Human Albumin Industry Report 2014 2Global Human Albumin Industry Report 2014 3Kultevat obtains license of gene switch technology 2Oncothyreon Prices $40 Million Concurrent Public Offerings of Common Stock and Preferred Stock 2Oncothyreon Prices $40 Million Concurrent Public Offerings of Common Stock and Preferred Stock 3Pharma and Omics Journals to Address Global Challenges during Open Access Week 2Pharma and Omics Journals to Address Global Challenges during Open Access Week 3
... to Remain as Advisor to Company, FRAZER, Pa., ... its Executive Vice President, General Counsel &,Secretary, John E. ... effective March 31. Mr. Osborn has agreed to remain ... policy matters., "John has been an invaluable member ...
... Inc. (Nasdaq:,EVVV) will release its 2007 fourth quarter and ... market trading hours., The company will host a ... CT (8:30 a.m. ET). ev3 management will review its ... outlook, followed,by a question and answer session., The ...
... Spanish . , ANN ARBOR, Mich.---A new ... to operate a portable GPS locator, a cell phone, ... involving the University of Michigan shows. , A report ... issue of the journal Science. Authors include researchers from ...
Cached Biology Technology:Cephalon General Counsel John E. Osborn to Resign Position 2Cephalon General Counsel John E. Osborn to Resign Position 3ev3 Inc. to Report 2007 Fourth Quarter and Full-Year Financial Results and Host Conference Call on February 22, 2008 2Knee brace generates electricity from walking 2
... Pierce offers maleimide activated carrier proteins ... conjugates. Imject Maleimide Activated Carrier Proteins ... been preactivated with a heterobifunctional cross-linker ... stable, sulfhydryl-reactive carrier protein. Thus ...
...
... A perfect complement to high-speed analytical techniques, the AutoTrace SPE is a ... automates the cartridge conditioning, sample loading and elution steps for large volumes aqueous ... ... ...
Cell Culture Flask, 25 cm, tissue-culture treated polystyrene...
Biology Products: