Navigation Links
Sea urchin genome suprisingly similar to man and may hold key to cures

he sea urchin’s immune system works. The human immune system has two components: innate immunity, with which we are born, and acquired immunity, which is the ability to produce antibodies in response to an infection. Sea urchins only have innate immunity, and it is greatly expanded with 10 to 20 times as many genes as in human.

"Considering that sea urchins have a long life span -- some can live up to 100 years -- their immune system must be powerful," Calestani said. "Sea urchins could very well provide a new set of antibiotic and antiviral compounds to fight various infectious diseases."

The sea urchin has been used for many years as a research model to study embryonic development.

Cell development is very complicated. In order to properly regulate just one gene expression of a single-cell layered gut of the sea urchin larva, at least 14 proteins binding the DNA at 50 sites are needed, Calestani said.

"Multiply that hundreds of times and you begin to understand the level of complexity involved in human development," she added.

Using a "simple" creature like the sea urchin embryo to uncover the molecular basis underlying development offers several experimental advantages compared to the use of mice. Raising sea urchin embryos is easy and inexpensive. One female can provide up to 20 millions eggs. The embryos develop in just three days and are transparent. Also, single cells can be easily observed live in the embryos.

"If we know how these biological processes work, then we can begin to figure out how to intercede to repair and to heal," Calestani said. "It holds a lot of promise."

Calestani is continuing her work with sea urchins at UCF in Orlando by examining the development of pigment cells found in the marine creatures. Those cells also might provide some insight into human immunity to diseases.

Calestani, who teaches genetics at UCF, worked with Davidson at Caltech before arriving
'"/>

Source:University of Central Florida


Page: 1 2 3

Related biology news :

1. Man and mouse share genome structures
2. Whole genome fine map of rice completed
3. Study finds more than one-third of human genome regulated by RNA
4. A bacterial genome reveals new targets to combat infectious disease
5. Scientists decipher genome of fungus that can cause life-threatening infections
6. Highly adaptable genome in gut bacterium key to intestinal health
7. Fleshing out the genome
8. Agilent Technologies new genome analysis technology set to accelerate Australia fight against mesothelioma
9. wFleaBase: the Daphnia genome database
10. NHGRI targets 12 more organisms for genome sequencing
11. Chimp genome reveals a retroviral invasion
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Sea urchin genome suprisingly similar man and may hold key cures

(Date:7/9/2014)... co-authored by a University of Guelph scientist that ... shows long-term exposure to a neonicotinoid pesticide hampers ... research by Nigel Raine, a professor in Guelph,s ... Imperial College London was published July 9 in ... . , The study shows how long-term pesticide ...
(Date:7/9/2014)... fever but often can be defeated with antibiotics and ... beat. Now, scientists have built a new weapon against such ... the journal ACS Applied Materials & Interfaces , their ... of them than medicine alone. , David Leong, Jianping Xie ... wait, undetectable in the human body or in places that ...
(Date:7/9/2014)... developed by researchers at the NIH,s National ... its collaborators to treat sickle cell disease ... business. The drug candidate, Aes-103, is the ... molecular mechanism of sickle cell disease. Baxter ... required for regulatory approval and commercialization. , ...
Breaking Biology News(10 mins):Bee foraging chronically impaired by pesticide exposure: Study 2First drug candidate from NIH program acquired by biopharmaceutical company 2First drug candidate from NIH program acquired by biopharmaceutical company 3First drug candidate from NIH program acquired by biopharmaceutical company 4
... Adoptive cell transfer (ACT) therapy is used to treat patients ... of the patient's cancer cells, and some of their immune ... of the cancer cells that stimulate the T cells to ... get expanded and re-infused into the patient to mount an ...
... pandemic influenza, a new study reports for the first time ... from poultry to humans. The research appears in the ... available online. , Crossing the species barrier is an important ... potential. Previous studies have focused on the ability of highly ...
... many scientists thought, genetically modified (GM) corn has not ... , After analyzing tens of thousands of seeds from ... Mexico and the United States found no evidence of ... the researchers, said Allison Snow, a professor of evolution, ...
Cached Biology News:First Whole Genome Map of Genetic Variability in Parkinson’s Disease 2Genetically modified maize not found in southern Mexico 2
(Date:1/15/2014)... 2014 Look inside the new Preferred ... the lab, from fluid handling to instruments to supplies. ... when you order. , Preferred Solutions features a ... the L/S® model for precise flow control and dispensing ...
(Date:1/15/2014)... January 15, 2014 A study has been ... the Formula 1 track could help to tackle the problem ... (MAT), Stowhealth (a GP surgery based in Stowmarket) and academics ... Simplyhealth. Telemetry technology, which is inspired by equipment ...
(Date:1/15/2014)... 2013 was a banner year of continued ... saw continued independent research led by the team at ... $1 million grant from the Susanne Marcus Collins Foundation, ... peer reviewed journal, Amy Grant highlighted Brainwave Optimization® in ...
(Date:1/14/2014)... 14, 2014 Carahsoft and CDS Federal ... 23, 2014 at 2pm EST (11am PST), “Natural Language ... focuses on how technology can turn raw, heterogeneous data ... government agencies. The online webinar will last approximately one ...
Breaking Biology Technology:Cole-Parmer Begins 2014 with the Release of Preferred Solutions 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2
... PfuTurbo and Taq DNA Polymerases ,,,, pfuturbo ... PCR amplification , , Holly Hogrefe ... In this update, we compare the PCR performances ... DNA polymerase. ,PCR product yields were higher ...
... mutagenesis in less than one day , ... 28-base insertion was introduced into a plasmid vector ... created three unique restriction enzyme digestion sites. Plasmid ... transformed clones were digested with,all 3 restriction enzymes, ...
... Studying Signal Transduction,Pathways ,,,,, Obtaining the best ... ,in vivo reporting systems , Tim Sanchez ... Zheng ,Stratagene , Stratagenes PathDetect ... are used to study,activation of specific signaling pathways ...
Cached Biology Technology:PCR Performance Comparisons Between pfuturbo and Taq DNA,Polymerases 2PCR Performance Comparisons Between pfuturbo and Taq DNA,Polymerases 3PCR Performance Comparisons Between pfuturbo and Taq DNA,Polymerases 4Efficiently Insert Unique Restriction Sites into Plasmid Vectors 2Efficiently Insert Unique Restriction Sites into Plasmid Vectors 3Optimizing Transfection Conditions for Studying Signal Transduction Pathways 2Optimizing Transfection Conditions for Studying Signal Transduction Pathways 3Optimizing Transfection Conditions for Studying Signal Transduction Pathways 4Optimizing Transfection Conditions for Studying Signal Transduction Pathways 5Optimizing Transfection Conditions for Studying Signal Transduction Pathways 6Optimizing Transfection Conditions for Studying Signal Transduction Pathways 7
... ,Yeast extract, 5 ,Sodium chloride, 10 ... citrate, 0.5 ,IPTG, 0.03 ,-Gal ... chromogenic substrate for -galactosidase. The enzymatic ... a black insoluble precipitate. Lac+ colonies ...
... Polyclonal Antibody Epitope: aa 16-25 of ... Recommended Storage: Store vial at -20 ... use. For extended storage aliquot contents and freeze at -20 ... Family: Other Sub-Family: ...
S-100 alpha/beta chain (8B10)...
... Acetate: CoA ligase (AMP forming), Acetate ... on protein content. Physical form: ... sucrose and reduced glutathione Preparation ... mol of S-acetyl coenzyme A from acetate, ...
Biology Products: