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Scripps research scientists solve structure of a critical innate immune system protein

coforms that make it harder, but not impossible, to form good crystals. A number of leucine-rich repeat proteins have been determined, but never one with this many leucine-rich repeats or so many carbohydrates.

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The article, "Crystal structure of human Toll-like receptor 3 (TLR3) ectodomain" is authored by Jungwoo Choe, Matthew S. Kelker, and Ian A. Wilson and is being published in SCIENCE EXPRESS, the early online publication site of the journal Science. See: http://www.sciencemag.org. The article will also appear in print in an upcoming issue of Science.


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Source:Scripps Research Institute


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