Navigation Links
Scientists unpick genetics of first 15 minutes of life

process occurs, the researchers used a type of mutant fruit fly, known to biologists as a s�same mutant, which they know does not form a proper male pro-nucleus.

By highlighting the chromatin and watching the changes it goes through at different stages of the fertilisation process, the scientists found that the pro-nucleus in s�same mutant is wound into a tight ball that could not interact with its female counterpart, the egg pro-nucleus.

This showed that there was a problem with the re-packaging process in the s�same mutant.

The researchers looked at the genetic makeup of the s�same mutant and identified what is known as a point mutation in the HIRA gene ?showing that HIRA is the gene responsible for chaperoning the assembly of the sperm pro-nucleus.

"This is one of the most crucial process that takes place in sexually reproducing animals," said Dr Karr who works in the Department of Biology and Biochemistry at the University of Bath.

"Sperm DNA has to undergo a complete transformation when it arrives in the egg cell so that it can properly join with the female pronucleus to form a new genetically complete the beginning of a new life.

"A slight mutation in the HIRA gene means that life does not even get started.

"Amazingly we still know relatively little about the structure of sperm DNA and the genetic processes involved in the most crucial early phases of reproduction."

Because of the particular type of histone protein used in the re-packaging of sperm DNA, the researchers believe that this process leaves its mark in the genome of the newly-formed organism.

This genetic marker could be a useful way of tracking the genetic material an offspring inherits from either their father or mother.


'"/>

Source:University of Bath


Page: 1 2

Related biology news :

1. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
2. Scientists Replicate Hepatitis C Virus in Laboratory
3. Scientists detect probable genetic cause of some Parkinsons disease cases
4. Scientists find missing enzyme for tuberculosis iron scavenging pathway
5. Scientists seek answers on what activates deadly anthrax spores
6. Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
7. Scientists collaborate to assess health of global environment
8. Scientists decipher genome of fungus that can cause life-threatening infections
9. Scientists discover the cellular roots of graying hair
10. Scientists rid stem cell culture of key animal cells
11. Scientists develop new color-coded test for protein folding
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Scientists unpick genetics first minutes life

(Date:8/18/2015)... N.J. , Aug. 18, 2015 /PRNewswire/ ... a key contributor to the Submission Content ... by IRISS, a non-profit forum. Dedicated to the ... provides a neutral platform for industry, vendors, ... share information and work towards a standard ...
(Date:8/17/2015)... OXFORD, Conn. , Aug. 17, 2015  NXT-ID, ... a biometric authentication company focused on the growing mobile ... announces its new sales campaign for Q4 2015. The ... winning marketing team consisting of Amplitude Marketing Group ( ... Amplitude Marketing Group is a leader in retail driven ...
(Date:8/12/2015)... , August 12, 2015 ... of mobile payment innovation and advanced biometrics technology is ... the way consumers rely on using their credit cards, ... reinventing the future for payment services led by companies ... NXTD ), :  Google, Inc. (NASDAQ: GOOG ), ...
Breaking Biology News(10 mins):Navitas, a Key Contributor in IRISS Forum Webinar 2Navitas, a Key Contributor in IRISS Forum Webinar 3NXT-ID, Inc. Launches Sales Campaign for Wocket Smart Wallet with Award Winning Marketing Team 2NXT-ID, Inc. Launches Sales Campaign for Wocket Smart Wallet with Award Winning Marketing Team 3Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 2Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 3Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 4Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 5Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 6
... how diseases are diagnosednew research published in the May 2010 ... ) details a noninvasive ground-breaking tool that detects signs of ... using traditional methods. Even better, this tool promises to detect ... before any permanent damage can occur. Its use may well ...
... crawls onto your lips while you sleep, drawn by the ... your blood. And if that,s not insult enough, it promptly ... Now Jean-Paul Paluzzi, a PhD candidate in biology ... to prevent the insects from leaving their messy calling card ...
... A small piece of RNA appears to play a ... according to lung disease researchers at the University of Pittsburgh ... examine microRNAs in the disease, is available online in the ... MicroRNAs are short strands of genetic material that ...
Cached Biology News:New tool helps scientists 'see' molecular signals of eye disease before symptoms arise 2The kiss of death: Research targets lethal disease spread by insect that bites lips 2Pitt researchers discover big role for microRNA in lethal lung fibrosis 2
(Date:8/28/2015)... ... August 28, 2015 , ... Riordan-McKenna ... McKenna, DO, announced today that the use of sterile, dehydrated amniotic tissue AlphaPATCH™ ... of an otherwise non-healing surgical knee wound. , The case involved a 78-year-old ...
(Date:8/27/2015)... 27, 2015  Neogen Corporation (NASDAQ: NEOG ) ... United Kingdom -based Lab M Holdings, ... and diagnostic systems. Lab M was ... provider of microbial testing and diagnostic products for the ... company currently sells into more than 70 countries worldwide, ...
(Date:8/27/2015)... ON , Aug. 27, 2015 /PRNewswire/ - BIOREM Inc. (TSXV: ... three and six-month periods ended June 30, 2015. Biorem,s complete second ... www.sedar.com ). FINANCIAL HIGHLIGHTS: in ,000,s except earnings per shareThree-months ... , 2014 , 2015 , 2014 ... 9,398 , 4,433 Gross profit , 1,656 ...
(Date:8/27/2015)... ... August 27, 2015 , ... ... needs and expertly narrows down the product choices to a manageable shortlist of ... down the list to models that fit best with the customer’s industry and ...
Breaking Biology Technology:Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 2Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 3Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 4Neogen acquires U.K.-based Lab M Holdings 2BIOREM Reports $718,000 Net Earnings for the Second Quarter 2BIOREM Reports $718,000 Net Earnings for the Second Quarter 3METTLER TOLEDO Updates Online Scale Selection Tool 2
... Ardea Biosciences,Inc. (Nasdaq: RDEA ) today announced ... non-nucleoside reverse transcriptase inhibitors (NNRTIs),at the 21st International ... of the Company,s mitogen-activated ERK kinase,(MEK) inhibitors, RDEA119 ... for Cancer Research (AACR) annual meeting., ...
... Calif., April 7, 2008 InterWest Partners,announced ... to the venture capital firm,s Advisory Committee: ... Leroy Hood, and,former FDA commissioner Dr. Mark ... experienced professional advisors, providing strategic guidance,to the ...
... CPHD ) will announce financial results for ... Thursday, May 1, 2008. The announcement will be,followed ... afternoon at 4:30 p.m.,Eastern Time., John Bishop, ... Financial Officer and Michael Myhre, Vice President,Corporate Controller, ...
Cached Biology Technology:Ardea to Present Data on HIV Non-Nucleoside Reverse Transcriptase Inhibitor and Two MEK Inhibitors at Upcoming Medical Conferences 2Ardea to Present Data on HIV Non-Nucleoside Reverse Transcriptase Inhibitor and Two MEK Inhibitors at Upcoming Medical Conferences 3Prestigious Scientific Leaders Join InterWest Advisory Committee 2Prestigious Scientific Leaders Join InterWest Advisory Committee 3Prestigious Scientific Leaders Join InterWest Advisory Committee 4Cepheid Schedules Teleconference and Webcast for First Quarter 2008 Results 2
Rabbit Anti-melatonin (different linkage) Polyclonal Antibody...
... Product Goat polyclonal to Cholesterol Oxidase ... Reactivity / Specificity Cross-reacts with bacteria. ... Background Information Cholesterol oxidases exist as ... and are implicated in bacterial pathogenesis. In ...
Rabbit polyclonal to SERHL ( Abpromise for all tested applications). entrezGeneID: 94009 SwissProtID: Q9H4I8...
... anti-phospho-PTEN (Ser385) ... amino acid region encompassing the ... (Ser385), Accession ... Quality Assurance: Routinely ...
Biology Products: