Navigation Links
Scientists unpick genetics of first 15 minutes of life

process occurs, the researchers used a type of mutant fruit fly, known to biologists as a s�same mutant, which they know does not form a proper male pro-nucleus.

By highlighting the chromatin and watching the changes it goes through at different stages of the fertilisation process, the scientists found that the pro-nucleus in s�same mutant is wound into a tight ball that could not interact with its female counterpart, the egg pro-nucleus.

This showed that there was a problem with the re-packaging process in the s�same mutant.

The researchers looked at the genetic makeup of the s�same mutant and identified what is known as a point mutation in the HIRA gene ?showing that HIRA is the gene responsible for chaperoning the assembly of the sperm pro-nucleus.

"This is one of the most crucial process that takes place in sexually reproducing animals," said Dr Karr who works in the Department of Biology and Biochemistry at the University of Bath.

"Sperm DNA has to undergo a complete transformation when it arrives in the egg cell so that it can properly join with the female pronucleus to form a new genetically complete the beginning of a new life.

"A slight mutation in the HIRA gene means that life does not even get started.

"Amazingly we still know relatively little about the structure of sperm DNA and the genetic processes involved in the most crucial early phases of reproduction."

Because of the particular type of histone protein used in the re-packaging of sperm DNA, the researchers believe that this process leaves its mark in the genome of the newly-formed organism.

This genetic marker could be a useful way of tracking the genetic material an offspring inherits from either their father or mother.


'"/>

Source:University of Bath


Page: 1 2

Related biology news :

1. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
2. Scientists Replicate Hepatitis C Virus in Laboratory
3. Scientists detect probable genetic cause of some Parkinsons disease cases
4. Scientists find missing enzyme for tuberculosis iron scavenging pathway
5. Scientists seek answers on what activates deadly anthrax spores
6. Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
7. Scientists collaborate to assess health of global environment
8. Scientists decipher genome of fungus that can cause life-threatening infections
9. Scientists discover the cellular roots of graying hair
10. Scientists rid stem cell culture of key animal cells
11. Scientists develop new color-coded test for protein folding
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Scientists unpick genetics first minutes life

(Date:8/28/2014)... Invasives is now available from the Lady Bird Johnson ... for identifying harmful non-native plant, insect and other invasive ... States cause about $137 billion in economic and other ... kill native plants and more. , "By having streamlined ... invasive species occur, we,re more likely to catch these ...
(Date:8/28/2014)... The Entomological Society of America (ESA) is pleased to ... Honorary Member of the Society. Honorary Membership acknowledges those ... through significant involvement in the affairs of the Society ... honor are selected by the ESA Governing Board and ... will be honored at the Awards Ceremony at Entomology ...
(Date:8/28/2014)... handful of bacterial culprits that may drive inflammatory bowel ... using patients, own intestinal immune responses as a guide. ... journal Cell . , Trillions of bacteria exist ... role in the development and progression of IBD. Yet ... species affect a person,s susceptibility to IBD and its ...
Breaking Biology News(10 mins):Mobile app makes ID of harmful plants, insects in Texas a snap 2Fred Baxendale selected as Honorary Member of the Entomological Society of America 2Yale study identifies possible bacterial drivers of IBD 2
... better understanding how antimicrobials bind and thereby get inactivated ... University of Illinois may have found a way to ... not a cure, this work has potential as a ... Gerard Wong a professor of materials science and engineering, ...
... nodes can be crucial for spreading low doses of ... as scrapie and Creutzfeldt-Jakob disease - into the nervous ... open access journal BMC Veterinary Research. While we can ... role in the neuroinvasion of prions for high doses ...
... caused the extinction of mammoths and the decline of ... debated. Overhunting by Paleoindians, climate change and disease lead ... considered a little out there is now hitting closer ... including two Northern Arizona University geologists, reports evidence that ...
Cached Biology News:Cystic fibrosis patients may breathe easier, thanks to bioengineered antimicrobials 2Lymph nodes can be key in spreading prion infectivity 2Research team says extraterrestrial impact to blame for Ice Age extinctions 2Research team says extraterrestrial impact to blame for Ice Age extinctions 3
(Date:8/28/2014)... Sterlitech is proud to announce that it ... stable of products . These additional products increase ... membrane filters with surface charges. , “We ... our membrane process testing equipment, and correspondingly, a wider ... explains Sterlitech President Mark Spatz. “The addition of ...
(Date:8/28/2014)... TALLAHASSEE, Fla. Exciting new work by a Florida ... molecular system that can take your temperature, emit white ... , And, the molecule looks like a butterfly. , ... and Biomedical Engineering in the FAMU-FSU College of Engineering, ... ago, but has continued to discover that his creation ...
(Date:8/28/2014)... A new market research report detailing ... from Strategic Consulting, Inc., the leading information resource ... Review, Fourth Edition: Global Review of Microbiology Testing ... compares microbiology test volumes, market values and methods ... and forecasts future volumes and market values through ...
(Date:8/28/2014)... 28, 2014 PrimeSource Building Products, ... selected SoundConnect to support their communication ... audio and web conferencing platform GlobalMeet powered by ... employees’ needs. SoundConnect delivers award winning “results ... Building Products will be utilizing GlobalMeet powered ...
Breaking Biology Technology:Sterlitech Corporation Enhances Its Selection of Flat Sheet Membrane Filters 2Novel 'butterfly' molecule could build new sensors, photoenergy conversion devices 22 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 22 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 3PrimeSource Chooses SoundConnect as Collaboration Provider 2
... Emmanuel Labourier, Marianna Goldrick, Ambion, ... that mediate post-transcriptional gene regulation by pairing , ... untranslated region of messenger RNAs and acting , ... and exciting area of research with applications ...
... High Density Oligonucleotide , Microarrays , ... engineered to maximize yields of full-length cDNA , ... 100 ng of input RNA in a single round for GeneChip , ... cRNA synthesis powered by , ...
... , Dmitriy Ovcharenko, Rich Jarvis, ... Ambion, Inc. , , ... is a powerful , experimental ... genes. It is used routinely for gene function analysis, target , ...
Cached Biology Technology:miRNA Expression in White Blood Cells 2miRNA Expression in White Blood Cells 3miRNA Expression in White Blood Cells 4miRNA Expression in White Blood Cells 5Improving RNA Amplification 2Improving RNA Amplification 3Improving RNA Amplification 4Improving RNA Amplification 5Improving RNA Amplification 6Improving RNA Amplification 7Improving RNA Amplification 8Improving RNA Amplification 9Improving RNA Amplification 10Improving RNA Amplification 11Improving RNA Amplification 12Improving RNA Amplification 13Improving RNA Amplification 14Delivering siRNAs to Difficult Cell Types 2Delivering siRNAs to Difficult Cell Types 3Delivering siRNAs to Difficult Cell Types 4Delivering siRNAs to Difficult Cell Types 5Delivering siRNAs to Difficult Cell Types 6Delivering siRNAs to Difficult Cell Types 7
... This gradient system uses three Adept CE ... providing a flow rate in one microlitre ... ultra-fast scanning detector, provides added flexibility. ... to a photodiode array detection and provides ...
... excellent isocratic refractive index chromatography system, uses the ... 4700. Data processing is provided by the ... by the high pressure CE 4100 dual piston ... supplied. The system can be upgraded ...
Mouse monoclonal antibody to QPCT - glutaminyl-peptide cyclotransferase (glutaminyl cyclase)...
... This CLS number is ... to easily match Cornings product ... yet, please order under the ... contact customer service for assistance. ...
Biology Products: