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Scientists turn tobacco against cancer

ound that tumor growth was inhibited in a similar manner to that of mammalian-made monoclonal antibodies, Dr. Ko says.

“These results indicate that plant biotechnology can be a useful alternative to produce monoclonal antibodies,?he says.

“The antibody produced in tobacco is as good as the antibody produced in animal cells,?says Dr. Koprowski, noting that tobacco-derived antibody should be safer and less expensive to produce.

The Jefferson scientists are seeking industry partners to begin mass production of the antibody. The next step in the work, Dr. Koprowski notes, would be to conduct a phase 1 clinical trial of the monoclonal antibody in colorectal cancer patients. In the meantime, they are studying the effectiveness of monoclonal antibodies against other types of cancer, including breast tumor and lung tumor cells, in laboratory animals.


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Source:Thomas Jefferson University


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