Navigation Links
Scientists track stealth DNA elements in primate evolution

Louisiana State University scientists in the Department of Biological Sciences have unraveled the details of a 25-million-year-old evolutionary process in the human genome. Specific DNA sequences that appear to have persisted in a latent state for long periods of time may not be simply lying dormant. Instead, the researchers say that these elements have played a crucial role in human evolution by surreptitiously spawning hyperactive progeny copies, giving rise to the most abundant family of DNA elements in the human genome: Alu elements. The study, which was led by LSU scientist Dr. Mark A. Batzer, provides the first strong mechanistic evidence for the evolution of Alu elements to date. It appears in the May issue of the journal Genome Research.

Alu elements are short, 300-nucleotide-long DNA sequences capable of copying themselves, mobilizing through an RNA intermediate, and inserting into another location in the genome. Over evolutionary time, this retrotransposition activity has led to the generation of over one million copies of Alu elements in the human genome, making them the most abundant type of sequence present. Because Alu elements are so abundant, comprising approximately 10% of the total human genome, they have been thoroughly characterized in terms of their origin and sequence composition. What has remained elusive to scientists, however, are the actual mechanisms by which these elements persist and propagate over time to influence human evolution.

In an attempt to understand these mechanisms, Dr. Batzer and his colleagues examined a subfamily of Alu elements in the human genome known as the AluYb lineage, and compared these elements to those in the genomes of other primate species, including chimpanzees, bonobos, gorillas, orangutans, gibbons and siamangs. The AluYb subfamily accounts for approximately 40% of all human-specific Alu elements and is currently one of the most active Alu lineages in the human genome. Some AluYb elements are
'"/>

Source:Cold Spring Harbor Laboratory


Page: 1 2 3

Related biology news :

1. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
2. Scientists Replicate Hepatitis C Virus in Laboratory
3. Scientists detect probable genetic cause of some Parkinsons disease cases
4. Scientists find missing enzyme for tuberculosis iron scavenging pathway
5. Scientists seek answers on what activates deadly anthrax spores
6. Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
7. Scientists collaborate to assess health of global environment
8. Scientists decipher genome of fungus that can cause life-threatening infections
9. Scientists discover the cellular roots of graying hair
10. Scientists rid stem cell culture of key animal cells
11. Scientists develop new color-coded test for protein folding
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Scientists track stealth DNA elements primate evolution

(Date:7/25/2014)... tractography (DTT), which is derived from diffusion tensor ... motor tracts, such as the corticospinal tract, the ... The corticospinal tract is known to be a ... human brain. Several studies have reported on injury ... addition, some studies have demonstrated recovery of a ...
(Date:7/25/2014)... a molecular testing panel developed at UPMC greatly ... surgery for patients with thyroid nodules and cancer, ... Institute (UPCI), partner with UPMC CancerCenter., The test, ... other diagnostic testing agencies, improved the chances of ... percent, according to the study published this month ...
(Date:7/24/2014)... Scientists at The New York Stem Cell Foundation ... creating a viable cell replacement therapy for multiple ... For the first time, NYSCF scientists generated induced ... of patients with primary progressive multiple sclerosis and ... these stem cells into becoming oligodendrocytes, the myelin-forming ...
Breaking Biology News(10 mins):Test increases odds of correct surgery for thyroid cancer patients 2Test increases odds of correct surgery for thyroid cancer patients 3NYSCF scientists one step closer to cell therapy for multiple sclerosis patients 2
... discovered that a poorly understood class of RNA produced in ... the outcome of the infection. Their findings are reported ... Society for Microbiology. RNA (ribonucleic acid) contains information transcribed ... known of these RNAs translate sections of DNA code into ...
... St. Louis, MO, October 26, 2010 Periodontitis, a ... teeth, leads to accumulation of bacteria and potential bone ... bacterial infection, more recent strategies target the inflammatory response. ... Journal of the American Dietetic Association , researchers ...
... Food and Agriculture (NIFA) awarded a $1.5 million grant ... for increasing environmental, social, and economic sustainability in ornamental ... the U of I Department of Crop Sciences said ... crop production systems is waste generation due to the ...
Cached Biology News:New class of biomolecules triggered in response to respiratory virus infection 2New class of biomolecules triggered in response to respiratory virus infection 3New class of biomolecules triggered in response to respiratory virus infection 4Consuming polyunsaturated fatty acids may lower the incidence of gum disease 2U of I receives $1.5 million to further sustainability in ornamental crop production 2U of I receives $1.5 million to further sustainability in ornamental crop production 3
(Date:7/24/2014)... led by group leader Yung-Eun Sung has announced ... sulfur-doped and nitrogen-doped graphenes which can be applied ... fuel cells. Yung-Eun Sung is both a group ... Institute for Basic Science* (IBS) and a professor ... has great significance with regards to the development ...
(Date:7/24/2014)... , July 24, 2014 Research and ... "Global Genomics and Proteomics Analytical Instruments Market 2014-2018" ... http://photos.prnewswire.com/prnh/20130307/600769 Genomics is the study of ... study of the structure and functions of proteomes or ... tools and technology. Genomics involves the mapping of genes ...
(Date:7/24/2014)... (PRWEB) July 24, 2014 2014 ... Sulphate Industryā€¯ is a professional and in-depth research ... introduces Potassium Sulphate basic information, including its ... industry overview. This research covers the international market ... global industry analysis covering macroeconomic environment & economic ...
(Date:7/24/2014)... July 24, 2014 Draper University, ... is proud to announce that for 6 weeks ... countries will converge on the Draper University campus ... intensive, experiential program focused on entrepreneurship, building real-world ... school, currently running its sixth cohort, continues to ...
Breaking Biology Technology:Global Genomics and Proteomics Analytical Instruments Market 2014-2018: Key Vendors are Agilent, Bio-Rad , F. Hoffmann, La Roche, Illumina, PerkinElmer and Thermo Fisher Scientific 2Potassium Sulphate Market & SHMP Industry 2014 (Global, China) Analysis Now Available at DeepResearchReports.com 2Potassium Sulphate Market & SHMP Industry 2014 (Global, China) Analysis Now Available at DeepResearchReports.com 3Potassium Sulphate Market & SHMP Industry 2014 (Global, China) Analysis Now Available at DeepResearchReports.com 4Summer Entrepreneurship Program Kicked Off by Draper University in Silicon Valley 2Summer Entrepreneurship Program Kicked Off by Draper University in Silicon Valley 3
... Laureate To Manufacture Tolera,s Monoclonal Antibody Product ... Laureate Pharma, Inc., a,full-service biopharmaceutical development ... has entered into a cGMP contract manufacturing,agreement ... that,develops and offers targeted therapies and safer ...
... will feature Ziplex automated gene-expression system at the ... ... Xceed Molecular, a pioneer in,the development of cost-effective, easy-to-use ... Dr. James L. Wittliff, a professor in the Department of,Biochemistry ...
... ... Gardner, Mass. (PRWEB) October 28, 2008 -- New England Peptide, ... formed scientific advisory board., , ,Vincent Bille, Tomi Sawyer and Ved ... thought leaders in peptide chemistry. The group will assist in formulating ...
Cached Biology Technology:Laureate Pharma Announces Agreement with Tolera Therapeutics, Inc. 2James L. Wittliff, Ph.D., FACB, to Present 'Predicting Breast Cancer Outcome with Gene Expression Signatures on the Ziplex(R) System' at the Association for Molecular Pathology Conference, October 30 2James L. Wittliff, Ph.D., FACB, to Present 'Predicting Breast Cancer Outcome with Gene Expression Signatures on the Ziplex(R) System' at the Association for Molecular Pathology Conference, October 30 3New England Peptide Forms Scientific Advisory Board 2New England Peptide Forms Scientific Advisory Board 3New England Peptide Forms Scientific Advisory Board 4
... This product has been developed to significantly ... labeled proteins. Stability is increased at ... 2-8 centigrade. This product is subjected ... mercury or azide. This formulation insures ...
... and conveniently controls the temperature at your lab ... levels up to 99 C*, with the "plus" ... as 5 C. The thermoblocks for 0.2 ml**, ... microplates enable a high degree of flexibility for ...
...
... powerful tool for sample purification in microbiological ... or protein purification as well as cell ... on the Genesis Series of instruments using ... with the RoMa arm and Tecans powerful ...
Biology Products: