Navigation Links
Scientists to track impact of Asian dust and pollution on clouds, weather, climate change

Mice whose brain cells respond to a flash of light are providing insight into the complexities of the sense of smell and may ultimately yield a better understanding of how the human brain works.

Investigators at Duke University Medical Center and the Howard Hughes Medical Institute have engineered a strain of mice whose olfactory brain cells "fire" when exposed to light. This was accomplished by inserting into the cells a gene naturally present in green algae that "turns on" when exposed to light and enables the algae to swim toward the light.

When the researchers shined light on the areas of the brain involved in smell, they could follow in real time what areas of the brain were reacting and where the signals went by seeing differences in electrical current that indicated the presence of the algae gene.

"This work provides a new method in live animals that will define the experimental approach for studying of mammalian neural circuitry in the coming decade," said Michael Ehlers, M.D., Ph.D., a Duke neurobiologist and Howard Hughes Medical Institute investigator.

The researchers published their findings in the April 19, 2007, issue of the journal Neuron. The research was supported by the National Institutes of Health and the Howard Hughes Medical Institute.

"This mouse model and its future variants mark the first use of genetically produced light activation in the study of the intact mammalian brain, and we believe this advance in nerve circuit mapping will be to neurobiology what microarray technology has been to genomic science -- a fundamental breakthrough," Ehlers said. Microarray technology enables scientists to screen thousands of genes at once to look for clusters of genes that may be involved in disease.

Although there are many approaches to studying how different nerve cells in the brain react to stimuli from the environment, this mouse model is the first to be able to provide real-time mapping of bra
'"/>

Source:National Center for Atmospheric Research


Page: 1 2 3

Related biology news :

1. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
2. Scientists Replicate Hepatitis C Virus in Laboratory
3. Scientists detect probable genetic cause of some Parkinsons disease cases
4. Scientists find missing enzyme for tuberculosis iron scavenging pathway
5. Scientists seek answers on what activates deadly anthrax spores
6. Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
7. Scientists collaborate to assess health of global environment
8. Scientists decipher genome of fungus that can cause life-threatening infections
9. Scientists discover the cellular roots of graying hair
10. Scientists rid stem cell culture of key animal cells
11. Scientists develop new color-coded test for protein folding
Post Your Comments:
(Date:8/19/2014)... improve students, chances of completing introductory biology courses ... (UH) implemented a comprehensive student success program, employing ... , Through a grant from the Texas ... Biology and Biochemistry embarked on a pilot program ... non-majors and "Introductory Biology" for science majors. These ...
(Date:8/19/2014)... Research and Network-Level Science, , Imagine if we had ... ecosystems was responding to global changes in real time. ... coupled multiple decades of information about ecological responses to ... dozens of different ecosystem types. , In fact, ... (LTER) Network, which will soon celebrate its 35th anniversary. ...
(Date:8/19/2014)... purchased at retail seafood counters in 10 different ... expose consumers to unexpectedly high levels of mercury, ... present a fish of the same species, but ... mislabeling offense, according to new research by University ... of seafood is essential to allow consumers to ...
Breaking Biology News(10 mins):University of Houson program earns kudos for improving grades, retaining students 2University of Houson program earns kudos for improving grades, retaining students 3This week from AGU: Long-term ecological research, predicting cholera outbreaks 2Seafood substitutions can expose consumers to unexpectedly high mercury 2Seafood substitutions can expose consumers to unexpectedly high mercury 3
... New Rochelle, NY, September 3, 2009Next-Generation Sequencing ... traditional Sanger sequencing methodology but are also giving ... well, reports Genetic Engineering & Biotechnology News ... workflow that eliminates transformation and colony picking and ...
... not be the first thing that comes to mind when ... the United States, South Korea and France, this might change. ... of a protein called "RanBP9" might be the key that ... them, hope. In a research report published online in The ...
... Results from the first swine-flu vaccine trials taking place in ... The pilot study, run by the University of Leicester ... between 18 and 50. Dr Iain Stephenson, who ... clinical trial of Novartis MF59-adjuvanted cell-based A (H1N1) vaccine indicates ...
Cached Biology News:GEN reports on expanding NextGen sequencing applications 2Scientists begin to untangle root cause of Alzheimer's disease 2World-first swine-flu vaccine trial reveals one dose provides 'strong immune response' 2
(Date:8/20/2014)... BOSTON , Aug. 20, 2014  PAREXEL International ... it will be presenting at the Baird Healthcare Conference ... President and Chief Financial Officer, will be making a ... p.m. EDT on Wednesday, Sept. 3, 2014. ... through the "Investors" section of PAREXEL,s website at ...
(Date:8/20/2014)... WriteResult®, a leading provider of Electronic Patient Outcome ... myPROpad™ ePRO tablet with the addition of a touchscreen ... widely used and well-respected Patient Reported Outcome (PRO) instruments ... used during clinical trials and in other health care ... to demonstrate Health-Related Quality of Life outcomes (HRQoL) resulting ...
(Date:8/19/2014)... Pa. , Aug. 19, 2014 A ... has been nominated for a Centers for Disease Control ... addressing a major public health concern. ... System, is one of a team of researchers nominated ... Charles C. Shepard Science Award for Data Methods and ...
(Date:8/19/2014)... 19, 2014 Research and ... the "Spectroscopy Equipment and Accessories - ... their offering. This report ... and Accessories in US$ Thousands by the ... Raman Spectrometers, NMR-EPR Spectrometers, Near Infrared (NIR) ...
Breaking Biology Technology:PAREXEL International To Present At Baird Healthcare Conference 2EQ-5D™ Assessment Now Available for iPad 2Geisinger investigator nominated for federal award 2Geisinger investigator nominated for federal award 3Global Spectroscopy Equipment and Accessories - Strategic Business Report 2014 2
... $8.1 Million Financing in Connection With Acquisition ... Reverse Stock Split Planned for January 2008, LONDON, ... that the Company has:, - Signed an agreement to acquire ... Israel. The acquisition,is expected to close tomorrow. The initial consideration is ...
... Calif., Dec. 4 Sangamo BioSciences,Inc. (Nasdaq: SGMO ... community on its latest developments in several of its,therapeutic ... and Analyst Briefing that will be held from 4:30 ... The presentation will be webcast live and may be ...
... - Associated Forum Provides Resources for Healthcare Professionals, ... ... 4 The Liko-sponsored Safe Lifting,Portal today announced the launch of ... associated safe lifting,forum, called "Safe Lifters," will allow healthcare professionals to,discuss ...
Cached Biology Technology:Amarin Signs Agreement to Acquire Ester Neurosciences 2Amarin Signs Agreement to Acquire Ester Neurosciences 3Amarin Signs Agreement to Acquire Ester Neurosciences 4Amarin Signs Agreement to Acquire Ester Neurosciences 5Amarin Signs Agreement to Acquire Ester Neurosciences 6Amarin Signs Agreement to Acquire Ester Neurosciences 7Amarin Signs Agreement to Acquire Ester Neurosciences 8Amarin Signs Agreement to Acquire Ester Neurosciences 9Amarin Signs Agreement to Acquire Ester Neurosciences 10Amarin Signs Agreement to Acquire Ester Neurosciences 11Sangamo BioSciences to Webcast Presentations at Investor and Analyst Briefing 2New Online 'Help Desk' Offers Safe Lifting Assistance to Healthcare Facilities 2
TEMPLIPHI HT SEQ AMPL KIT, 1 EA. Category: Sequencing Template Amplification....
This Malachite Green Phosphate Detection Kit...
Request Info...
1+ mg expected yield of purified protein, expressed in insect cells - excludes cDNA...
Biology Products: