Navigation Links
Scientists pinpoint inflammation gene

Discovery has implications for wide range of diseases

A team of international researchers has discovered that a specific gene on chromosome 15 regulates inflammation, a finding with implications for a wide range of disorders, including cancer, cardiovascular disease, diabetes, obesity, Alzheimer's, and infections. The findings are published in the October 9 online issue of Nature Genetics.

Investigators believe this discovery will be of great interest to biomedical and pharmaceutical researchers because of an already heightened understanding of the role of inflammation in so many human disorders.

"Practically every common disease involves an inflammation component," said John Blangero, Ph.D., a scientist at the Southwest Foundation for Biomedical Research (SFBR) in San Antonio and the paper's senior author. "So the discovery of a new player in the inflammation pathway opens up many potential avenues for intervention on a broad range of health issues."

Along with Blangero, lead researchers in identifying the SEPS1 (Selenoprotein S) gene's influence on inflammation were Joanne Curran, Ph.D., and Ahmed H. Kissebah, M.D. Curran, who also is a geneticist at SFBR, was formerly with ChemGenex Pharmaceuticals (NASDAQ: CXSP; ASX: CXS), an Australian-based company that initially identified the gene through animal studies and funded this latest analysis of its role in humans. Kissebah is professor of medicine at the Medical College of Wisconsin and medical director of TOPS (Take Off Pounds Sensibly), an international weight-loss organization whose members provided genetic material for analysis. Dr. Kissebah practices at Froedtert Hospital, a major teaching affiliate of the Medical College. Other scientists from SFBR, ChemGenex, Deakin University (Geelong, Australia) and the International Diabetes Institute (Melbourne, Australia) also contributed to the work.

Their research study identified SEPS1 as a type of "garbage truck" tha
'"/>

Source:Medical College of Wisconsin


Page: 1 2 3 4

Related biology news :

1. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
2. Scientists Replicate Hepatitis C Virus in Laboratory
3. Scientists detect probable genetic cause of some Parkinsons disease cases
4. Scientists find missing enzyme for tuberculosis iron scavenging pathway
5. Scientists seek answers on what activates deadly anthrax spores
6. Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
7. Scientists collaborate to assess health of global environment
8. Scientists decipher genome of fungus that can cause life-threatening infections
9. Scientists discover the cellular roots of graying hair
10. Scientists rid stem cell culture of key animal cells
11. Scientists develop new color-coded test for protein folding
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Scientists pinpoint inflammation gene

(Date:12/17/2014)... 15, 2014 Research and Markets ... the "Samsung Galaxy S5 - Home Button ... their offering. http://photos.prnewswire.com/prnh/20130307/600769 ... sensing technology than the iPhone 5S, Samsung introduces ... its product. The Galaxy S5 home ...
(Date:12/17/2014)... DENVER , Dec. 16, 2014  Automation ... is this more evident than at international borders. ... secure document scanners have allowed veteran travelers to ... Automated Passport Control (APC) Kiosks at an increasing ... the globe. According to ...
(Date:12/11/2014)... Minn. , Dec. 10, 2014  Data ... physiologic monitoring, has released a new series of ... of preclinical toxicology researchers. M series, part of ... toxicologists collect the best possible physiologic data when ... Adding functional endpoints to toxicology studies has ...
Breaking Biology News(10 mins):Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2New telemetry implants expected to change how large animal toxicology studies are conducted 2
... led by a Michigan State University professor has discovered a link ... one of the disease,s most common and potentially blindness-causing complications. ... vessels in the retina that affects up to 80 percent of ... to the nerves found in bone marrow that leads to the ...
... beetle, a pest that feasts on corn roots and corn ... the U.S., also can survive on the perennial grass ... likely be grown alongside corn, researchers report. Rootworm beetle ... and adult beetles will lay their eggs at the base ...
... COLD SPRING HARBOR, N.Y. (Jan. 5, 2010) ... proteomics have dramatically increased the need for quantitative reasoning ... the most routine informatics tools rely on statistical assumptions ... scientific results are to be correct, understood, and exploited ...
Cached Biology News:MSU researcher links diabetic complication, nerve damage in bone marrow 2Miscanthus, a biofuels crop, can host western corn rootworm 2Miscanthus, a biofuels crop, can host western corn rootworm 3New handbook for biologists who need more competence or confidence in statistics 2
(Date:12/19/2014)... December 18, 2014 LayerBio is an ... and wound care. The National Eye Institute (NEI) at ... a Phase I SBIR grant to develop a drug-eluting ... the most common cause of vision loss in people ... worldwide. According to Dr. Ken Mandell, LayerBio’s Founder and ...
(Date:12/19/2014)... 2014 The empty capsules market ... ageing population and technological innovations in the empty ... are catalysing the growth of the empty capsules ... , Scope of Report , The report ... new entrants/smaller firms to gauge the pulse of ...
(Date:12/19/2014)... , Dec. 18, 2014 Relmada Therapeutics, Inc. ... the treatment of chronic pain, announced the results of ... "This was a transformational year in Relmada,s history ... for our company," said Sergio Traversa , chief ... have executed on key financial, human resource and clinical ...
(Date:12/17/2014)... N.J. (PRWEB) December 17, 2014 ... (Euronext: IPN; ADR: IPSEY), today announced ... (referred to as Somatuline®) was approved by the ... treatment of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) in adult ... advanced or metastatic disease to improve progression-free survival ...
Breaking Biology Technology:LayerBio Awarded NIH Grant to Develop a Drug Delivery Device for Cataract Surgery 2Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 2Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 3Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 4Relmada Therapeutics Announces Results of Annual Shareholders Meeting 2Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 2Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 3Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 4Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 5Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 6Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 7Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 8
... May 12 /PRNewswire/ - Cytochroma today announced that ... Chief Financial Officer (CFO).,Mr. Wieland, 63, brings to ... financial management, at both public and private companies, ... "Rich has strong leadership skills, extensive experience managing,finance ...
... Lasers that emit ultrashort pulses of light are ... eye surgery, spectroscopy and controlling chemical reactions. But ... distortions caused by lenses and other optical components ... , To better understand the distortions, researchers at ...
... On Diagnostic Products and Target Validation, ... announced today,that SomaLogic and Otsuka Pharmaceutical Co., ... SomaLogic,s proprietary aptamer technology,to discover and develop ... that will enhance Otsuka,s pharmaceutical discovery and ...
Cached Biology Technology:Cytochroma Appoints R. Richard Wieland II As CFO 2New technique measures ultrashort laser pulses at focus 2New technique measures ultrashort laser pulses at focus 3SomaLogic and Otsuka Enter Into Research Collaboration 2SomaLogic and Otsuka Enter Into Research Collaboration 3
... The product contains 5 ml ... with the monoclonal BerEP4 against ... (epithelial cell adhesion molecule). Also ... of 2 x 10e7 MNC ...
MOUSE ANTI HUMAN FACTOR I...
Superior homology search software - in all the flavours of blast, with increased sensitivity and speed. Free windows version for academic use....
GFX PCR DNA,Gel Band Purif,100, 1 EA. Category: Nucleotide Sample Handling....
Biology Products: