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Scientists identify gene involved in stem cell self-renewal in planaria

nued to completion," Newmark said. "What may be happening is that when this protein is eliminated, RNAs that are supposed to be turned off (that is, not made into proteins) are now turned on and made into proteins. Those proteins may then cause the stem cells to differentiate, instead of also producing new stem cells to maintain the population."

While there is still much to be learned about stem cell self-renewal, the researchers' results suggest that Bruli protein is required for stem cell maintenance in planarians.

"The next steps are to see if the gene that makes this protein in planarians plays a similar role in stem cells in other organisms and to identify possible RNA targets of this protein," Newmark said.


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Source:University of Illinois at Urbana-Champaign


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