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Scientists find potential 'off-switch' for HIV virus

ibernation with high frequency and reducing the threat to the host."

Weinberger said that drugs already exist that target other cellular enzymes, so there is reason to hope the approach will work.

"There is precedent for this type of treatment," he said.

Though more research will be needed to develop drugs based on the Princeton scientists' "resistor" model, Weinberger said he hopes the discovery stimulates more research into potential gene-targeted therapies.

"It would be wonderful to learn more about how these genetic circuits work so that we can enter a new age of drug design," he said. "Rather than just giving a static drug, we might one day design therapies that are precisely timed to turn off viruses just like a natural genetic circuit might."
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Source:Princeton University


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