Navigation Links
Scientists find a maturity gene in fly

University of Utah researchers showed that a fruit fly gene is crucial for determining when juveniles begin to mature into adults, and how the transformation initially proceeds. Understanding this process in humans may help explain how adorable children become surly teenagers.

When the DHR4 gene is disabled, fruit flies prematurely begin metamorphosis ?maturation from an immature larva to a sexually active adult. It is the first genetic mutation found to cause early maturation in fruit flies, according to a new study in the Friday June 3 issue of the journal Cell. The flies are abnormally small and die as they enter adulthood, sometimes when their heads fail to emerge from their bodies.

"We identified a gene that is needed for the animal to progress through normal juvenile development to maturation," says University of Utah geneticist Carl Thummel, the study's principal author. "Without this gene, the juvenile stage is shortened, and it enters adulthood early. The animal then dies because the gene also is needed for continued maturation."

The process is relevant to people because insect metamorphosis is analogous to the transformation of a human "from a juvenile, non-reproductive stage to a mature, sexually reproductive adult," says Thummel, a professor of human genetics at the university and an investigator with the Howard Hughes Medical Institute.

"Our kids stay sweet and cute through about 12 years of life and then, suddenly, in response to steroid and thyroid hormones and their receptors [molecules that help hormones control genes], they begin this amazing transformation into smelly, hairy, sometimes surly, sexually mature teenagers," he adds. "How is this event timed, and how is it controlled at a molecular [genetic] level? Clearly there is genetic input, since the timing of maturation varies between families and cultures. But molecular mechanisms are presently unknown. Our study addresses this question using fruit flies, which h
'"/>

Source:University of Utah Health Sciences Center


Page: 1 2 3 4

Related biology news :

1. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
2. Scientists Replicate Hepatitis C Virus in Laboratory
3. Scientists detect probable genetic cause of some Parkinsons disease cases
4. Scientists find missing enzyme for tuberculosis iron scavenging pathway
5. Scientists seek answers on what activates deadly anthrax spores
6. Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
7. Scientists collaborate to assess health of global environment
8. Scientists decipher genome of fungus that can cause life-threatening infections
9. Scientists discover the cellular roots of graying hair
10. Scientists rid stem cell culture of key animal cells
11. Scientists develop new color-coded test for protein folding
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Scientists find maturity gene fly

(Date:7/11/2014)... started near the City of Entiat on Tuesday, July ... fire quickly grew to over 1,000 acres by evening. ... is under investigation by the Washington Department of Natural ... local resources in developing fire control strategies and tactics. ... State Department of Natural Resources, (WA DNR), Bureau of ...
(Date:7/11/2014)... scientists have set a "mouse TRAP" to capture the ... recent study published in the Journal of Clinical ... technique called TRAP to extract cellular and genetic information ... scientists at the Rockefeller Institute for Medical Research in ... protein-making machinery, or ribosomes, of the cell type of ...
(Date:7/11/2014)... group members to reduce aggression and gain access to ... grooming activities shows a certain pattern across the day. ... Biology Letters . , Grooming between individuals in ... motives. To be groomed has hygienic benefits and is ... can provide access to infants, mating opportunities and high ...
Breaking Biology News(10 mins):Baboons groom early in the day to get benefits later 2
... almost 30 years, researchers have sought to identify a ... during photosynthesis. A team at Ludwig-Maximilians-Universitt (LMU) in Munich ... to be an old acquaintance. Photosynthesis sustains ... molecular oxygen that higher organisms depend on. The process ...
... Marine resource managers often gauge the health of species ... relationships in the Bering Sea found that it isn,t the ... how densely they are aggregated. It,s more than searching ... balance how much energy they expend in searching for food ...
... make animals, well, brainier, but that boost in brain size ... evidence reported on January 3rd in Current Biology , ... for large and small brain sizes. The findings lend ... ability do go together, a topic that has been a ...
Cached Biology News:Photosynthesis: The last link in the chain 2Bering Sea study finds prey density more important to predators than biomass 2Bering Sea study finds prey density more important to predators than biomass 3Big brains are pricey, guppy study shows 2
(Date:7/11/2014)... , July 11, 2014 ... to announce the appointment of John P. Donoghue ... Biotech   in  Geneva . The ... Campus Biotech in Geneva , has ... recognised neuroscientists. John P. Donoghue , founder of ...
(Date:7/11/2014)... 11, 2014  Researchers have pioneered a revolutionary ... new technology, called Virtual Finger, allows scientists to ... neurons and synapses using the flat surface of ... 3D imaging studies orders of magnitude more efficient, ... level across many areas of experimental biology. The ...
(Date:7/10/2014)... (PRWEB) July 10, 2014 Women ... have access to an additional family planning option. ... to contraception at all levels of the health ... formulation of a widely used contraceptive—Pfizer’s Depo-Provera® (depot ... Burkina Faso is the first of four African ...
(Date:7/10/2014)... 10, 2014 Deep Knowledge Ventures ... Forum on ‘Commercialising Longevity Research’ and welcomed a ... the London Bioscience Innovation Center for the event, ... Aging Analytics Ltd. The meeting highlighted the need ... research for age-related disease, as well as the ...
Breaking Biology Technology:John P. Donoghue is Taking the Lead at the Wyss Center and is Appointed Professor at EPFL and University of Geneva 2John P. Donoghue is Taking the Lead at the Wyss Center and is Appointed Professor at EPFL and University of Geneva 3Virtual Finger Enables Scientists To Navigate And Analyze 3D Images Of Complex Biological Structures 2Virtual Finger Enables Scientists To Navigate And Analyze 3D Images Of Complex Biological Structures 3Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 2Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 3Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 4Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 5Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 6DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 2DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 3DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 4DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 5DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 6
... of dementia ... and participation in clinical trials., Silicon Valley,s Conway, Campbell ... Internet to Transform Medical Research and Philanthropic Outreach, ... of,California, San Francisco (UCSF) today launched a comprehensive Internet,video ...
... Life Sciences Inc.,(TSX: PLI) ("ProMetic") today presented ... trial in patients with chemotherapy-induced,anemia ("CIA") at ... Association,held in Copenhagen, Denmark this week., ... presented data on,PBI-1402 in a poster entitled ...
... VANCOUVER, June 13 /PRNewswire-FirstCall/ - Angiotech Pharmaceuticals,Inc. (NASDAQ: ... pharmaceutical and,medical device company, today announced the market ... available immediately for distribution,and sale in the U.S. ... made from a rapidly resorbing,polymer, is intended primarily ...
Cached Biology Technology:UCSF and YouTube Launch Channel Dedicated to Educating the Public About Neurodegenerative Diseases 2UCSF and YouTube Launch Channel Dedicated to Educating the Public About Neurodegenerative Diseases 3Positive clinical data for PBI-1402 presented at the Annual Congress of the European Hematology Association 2Positive clinical data for PBI-1402 presented at the Annual Congress of the European Hematology Association 3Angiotech announces market launch of Quill(TM) SRS MONODERM(TM) 2Angiotech announces market launch of Quill(TM) SRS MONODERM(TM) 3Angiotech announces market launch of Quill(TM) SRS MONODERM(TM) 4
This antibody detects an ~25 kDa band, corresponding to the expected molecular mass of Rab3A, on immunoblots. The antibody specificity is confirmed in peptide inhibition immunoblotting studies....
HLA II DG+DR+DP Monoclonal Antibody, Purified, Unconjugated, Clone: IQU9 This antibody is specific for the monomorphic determinant of the HLA Class II beta chains of the human MHC (28 kDa)....
Anti-gp120/160(SIV/mac239) Immunogen: gp120(SIV/mac239) protein (Genebank accession #M33262)...
Phospho-MEF2A(Thr312)...
Biology Products: