Navigation Links
Scientists explore how complex organs develop from a simple bud

The current issue of Differentiation, guest-edited by Brigid Hogan, highlights several scientific investigations into the complex biological mechanism known as branching morphogenesis. Through a series of seven laboratory reviews, important insights governing this process during animal development are revealed. The articles analyze how branching morphogenesis occurs in different organ systems in the same species. They also compare the process between simple and complex organisms.

Key questions within the reviews --pertaining to the maintenance and repair of cells within adult branched organs, the role of cells only transiently associated with adult organs, and the extent to which defects in the growth and development of fetal stage organs can affect organ function after birth -- have important implications for human health.

Two of the reviews in the Journal delve into tubulogenesis ?a process that is intimately tied to branching morphogenesis. Another contains research aimed at helping patients whose salivary glands have been injured by radiation therapy or autoimmune rejection. An investigation into the morphogenesis of the prostate gland and seminal vesicles is included, as well as an in-depth look at the genetic and cellular interactions critical to placental development. Research on this process in mouse kidneys generated a real-time tracking procedure which has significant implications for genetic manipulation.

Ultimately, scientists hope analysis of branching morphogenesis will lead to the design of a computer program that is able to virtually reconstruct the complete process of organogenesis –from simple bud to complex organ. The reviews in this special issue of Differentiation are written by top scientists offering fresh ideas and pertinent background information to readers interested in anything from molecular to cellular and developmental biology.


'"/>

Source:Blackwell Publishing Ltd.


Page: 1

Related biology news :

1. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
2. Scientists Replicate Hepatitis C Virus in Laboratory
3. Scientists detect probable genetic cause of some Parkinsons disease cases
4. Scientists find missing enzyme for tuberculosis iron scavenging pathway
5. Scientists seek answers on what activates deadly anthrax spores
6. Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
7. Scientists collaborate to assess health of global environment
8. Scientists decipher genome of fungus that can cause life-threatening infections
9. Scientists discover the cellular roots of graying hair
10. Scientists rid stem cell culture of key animal cells
11. Scientists develop new color-coded test for protein folding
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/20/2016)... 2016  VoiceIt is excited to announce its ... By working together, VoiceIt and VoicePass will ... VoicePass take slightly different approaches to voice biometrics, ... and usability. ... partnership. "This marketing and technology partnership ...
(Date:5/3/2016)...  Neurotechnology, a provider of high-precision biometric identification ... Identification System (ABIS) , a complete system for ... can process multiple complex biometric transactions with high ... face or iris biometrics. It leverages the core ... MegaMatcher Accelerator , which have been used in ...
(Date:4/26/2016)... Research and Markets has announced ... 2016-2020"  report to their offering.  , ,     (Logo: ... analysts forecast the global multimodal biometrics market to ... period 2016-2020.  Multimodal biometrics is being ... the healthcare, BFSI, transportation, automotive, and government for ...
Breaking Biology News(10 mins):
(Date:5/25/2016)... ... May 25, 2016 , ... WEDI, the nation’s leading ... today announced that Charles W. Stellar has been named by the WEDI Board of ... January 2016. As an executive leader with more than 35 years of experience in ...
(Date:5/24/2016)...   MedyMatch Technology Ltd ., the data analytics healthcare ... support tools in the emergency room, announced today that it ... Technology Industries (IATI) BioMed Conference. The Conference ... National Life Sciences and Technology Week, and is being held ... Tel Aviv, Israel . Gene Saragnese ...
(Date:5/23/2016)... (PRWEB) , ... May 23, 2016 , ... ... That Will Drive Precision Farming in 2017 and Beyond. The paper outlines the ... in the precision ag industry. , “We’ve witnessed a lot of highs and ...
(Date:5/23/2016)... ... May 23, 2016 , ... RoviSys, a leading independent provider ... Ohio, has broken ground on a new building in Holly Springs, NC. With ... new location solidifies a commitment to business in the region. The new facility ...
Breaking Biology Technology: