Navigation Links
Scientists discover toxin that causes gastro disease

Australian scientists have identified a highly potent toxin that causes severe gastrointestinal illnesses, including food poisoning.

The toxin, produced by certain strains of E. coli bacteria, has been found to be responsible for an outbreak of haemolytic uraemic syndrome, a dangerous disease that causes acute kidney failure, in South Australia in 1998.

The research team was led by Dr Adrienne Paton from the University of Adelaide, and included scientists from Monash University's ARC Centre of Excellence in Structural and Functional Microbial Genomics, and the United States.

Dr Travis Beddoe from Monash University's Department of Biochemistry and Molecular Biology, is one of the investigators who discovered that the bacterial toxin, subtilase cytotoxin, deactivates an essential component of cells in the gastrointestinal tract.

"It is unique because it cuts an essential component of the cell machinery in half, therefore disabling it," he said.

As well as learning how the toxin works, the scientists have also determined its three-dimensional structure, which will aid in the development of treatments for toxin-related diseases.

"This toxin belongs to the family of toxins that cause whooping cough, a very serious bacterial infection that affects children," Dr Beddoe said.

He said the research breakthrough may also provide insights into the development of age-related and degenerative diseases such as Parkinson's disease and Alzheimer's disease, and may be used in the treatment of some cancers.
'"/>

Source:Monash University


Page: 1

Related biology news :

1. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
2. Scientists Replicate Hepatitis C Virus in Laboratory
3. Scientists detect probable genetic cause of some Parkinsons disease cases
4. Scientists find missing enzyme for tuberculosis iron scavenging pathway
5. Scientists seek answers on what activates deadly anthrax spores
6. Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
7. Scientists collaborate to assess health of global environment
8. Scientists decipher genome of fungus that can cause life-threatening infections
9. Scientists discover the cellular roots of graying hair
10. Scientists rid stem cell culture of key animal cells
11. Scientists develop new color-coded test for protein folding
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/21/2016)...   Neurotechnology , a provider of high-precision ... that the MegaMatcher On Card fingerprint matching algorithm ... NIST Minutiae Interoperability Exchange (MINEX) III ... of the evaluation protocol. The ... fingerprint templates used to establish compliance of template ...
(Date:11/17/2016)... 2016 Global Market Watch: Primarily supported ... Population-Based Banks and Academics) market is to witness a value ... shows the highest Compounded Annual Growth Rate (CAGR) of 10.75% ... the analysis period 2014-2020. North America ... by Europe at 9.56% respectively. ...
(Date:11/16/2016)... , Nov. 16, 2016 Sensory Inc ... and security for consumer electronics, and VeriTran ... and retail industry, today announced a global partnership ... way to authenticate users of mobile banking and ... TrulySecure™ software which requires no specialized biometric ...
Breaking Biology News(10 mins):
(Date:11/30/2016)... and BEIJING , Nov. 30, 2016 ... provider of genomic services and solutions with cutting edge ... it has completed a USD $75 Million [515 Million ... Ltd.,s CMB International Capital Management ( Shenzhen ... Co., Ltd. ("SDIC Innovation") and Shanghai Sigma Square Investment ...
(Date:11/30/2016)... 30, 2016   Merck , a leading science ... into a set of agreements with Evotec AG, whereby ... of genetic reagents such as CRISPR and shRNA libraries. ... offers an accelerated pathway to explore and identify new ... identification of new targets, a process that can be ...
(Date:11/30/2016)... Park, NC (PRWEB) , ... November 30, 2016 ... ... company engaged in the development of a new orally administered treatment for Alzheimer’s ... and neuroimaging results of a Phase 2a clinical trial of T3D-959 in mild ...
(Date:11/30/2016)... Toronto, ON (PRWEB) , ... November 30, 2016 ... ... focused on discovery and development of precision treatments for neurodegenerative diseases, today announced ... disease (AD) (announced on November 3, 2016) blocked propagation of toxic, prion-like forms ...
Breaking Biology Technology: