Navigation Links
Scientists discover a new disease-causing bacterium in an immune-compromised patient

Researchers discovered a new bacterium in an immune-compromised patient, according to a study recently published in PLoS Pathogens. The bacterium belongs to the family Acetobacteraceae and includes bacteria common in the environment, some of which are used in industry, such as vinegar-making. "This is the first reported case of invasive human disease caused by any of the Acetobacteraceae," according to the article.

The new bacterium was identified in a patient with chronic granulomatous disease (CGD), a rare genetic disorder that impairs the immune system. In the patient, the bacterium caused fever, lymph node inflammation, and weight loss, but not death.

The journal also published an editorial entitled, "Extending the Spectrum of Human Pathogens," which comments on the significance of the discovery.

Usually, our immune systems fight off most bacteria and fungi with everyday ease, thwarting infection. But patients with CGD cannot control attacks by certain bacteria and fungi. The disorder prevents immune cells called neutrophils from functioning properly, and recurrent --and potentially life-threatening-- infections result.

The team isolated the new bacterium from the patient's swollen lymph nodes and demonstrated its pathogenesis. "Our first concern was to determine whether this organism was truly associated with his clinical syndrome," the team wrote.

Despite ineffective neutrophil immune cells, the patient's immune system still tagged the bacterium as an invader. Researchers also exposed CGD mice to the bacterium, recreating the appearance of the patient's infection. Researchers were then able to retrieve the bacteria from the mice's spleens, which are disease-fighting organs. These factors all support the pathogenic nature of the bacterium.

Because the bacterium does not cause death, it may be provide useful comparison with more menacing bacteria and fungi in CGD patients. "Given its appare
'"/>

Source:Public Library of Science


Page: 1 2

Related biology news :

1. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
2. Scientists Replicate Hepatitis C Virus in Laboratory
3. Scientists detect probable genetic cause of some Parkinsons disease cases
4. Scientists find missing enzyme for tuberculosis iron scavenging pathway
5. Scientists seek answers on what activates deadly anthrax spores
6. Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
7. Scientists collaborate to assess health of global environment
8. Scientists decipher genome of fungus that can cause life-threatening infections
9. Scientists discover the cellular roots of graying hair
10. Scientists rid stem cell culture of key animal cells
11. Scientists develop new color-coded test for protein folding
Post Your Comments:
(Date:3/31/2015)... NEW YORK , March 31, 2015  Elephant ... the "Company"), a global provider of Software Defined Network ... solutions, today announced total revenue of approximately $20.4 million ... to a restated $19.5 million for the year ended ... of calendar 2014, the Company had completed its multi-year ...
(Date:3/30/2015)... 26, 2015 Research and Markets ( ... "Global Gesture Recognition Market in Automotive Sector 2014-2018" ... the Global Gesture Recognition market in Automotive Sector to ... 2013-2018. Gesture recognition is the ability of ... of an individual. Gesture recognition technology can be 2D-based ...
(Date:3/24/2015)... --Research and Markets ( http://www.researchandmarkets.com/research/hdgz7h/global_iris ) has ... Market 2015-2019" report to their offering. ... grow at a CAGR of 23.5 percent over the ... scenario and the growth prospects of the Global Iris ... market size, the report considers the revenue generated from ...
Breaking Biology News(10 mins):Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 2Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 3Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 4Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 5Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 6Global Gesture Recognition Market in Automotive Sector Report 2015 - Growing Number of Partnerships 2Global Iris Recognition Market 2015-2019 with 3M Cogent, Bioenable Technologies, Cross Match Technology, Iris ID Systems & Safran Dominating 2
... a key source of water for millions of people in ... climate changes as expected and future water usage is not ... of Oceanography, UC San Diego. Without Lake ... no buffer to sustain the population of the Southwest through ...
... Feb. 11 Most fashion consumers consider,custom-made jeans ... lottery,winners. But Intellifit, a leader in proprietary apparel ... perception., This week, the company will begin ... company retail store outside of Philadelphia. Using Intellifit,technology, ...
... the Moores Cancer Center at University of California, San Diego ... were treated with a gene therapy protocol began making antibodies ... be published on line the week of February 11-15 in ... of Science. Researchers led by Thomas J. Kipps, M.D., ...
Cached Biology News:Lake Mead could be dry by 2021 2Lake Mead could be dry by 2021 3Intellifit(R) Offers Custom-Made Jeans with a High-Tech Twist 2Gene therapy protocol at UCSD activates immune system in patients with leukemia 2
(Date:5/4/2015)... China Cord Blood Corporation (NYSE: CO ... leading provider of cord blood collection, laboratory testing, ... today announced that the Company has been informed that ... Hong Kong listed company and a substantial ... (the "Agreement") to purchase the Company,s outstanding 7% senior ...
(Date:5/4/2015)... , May 4, 2015   Sentrian ™, ... hospitalizations, has teamed with the Scripps Translational Science ... technology on 1,000 patients with chronic obstructive pulmonary disease ... Americans and is the nation,s third leading cause of ... CareMore Health System , a wholly owned subsidiary ...
(Date:5/1/2015)... /PRNewswire/ - BioAmber Inc. (NYSE: BIOA ), an ... has priced an underwritten registered offering of 3,900,000 shares ... per share, and granted the underwriters in the offering ... 585,000 shares of its common stock. The gross proceeds ... expected to close on May 6, 2015, subject to ...
(Date:5/1/2015)... -- Investor-Edge has initiated coverage on ... GENE ), Agilent Technologies Inc. (NYSE: A ... ), Sequenom Inc. (NASDAQ: SQNM ), and ... report on Genetic Technologies can be accessed at ... the NASDAQ Composite ended at 4,941.42, down 1.64%, ...
Breaking Biology Technology:China Cord Blood Corporation Receives Notice of a Transaction Regarding its 7% Senior Convertible Notes Due 2017 Held by KKR 2China Cord Blood Corporation Receives Notice of a Transaction Regarding its 7% Senior Convertible Notes Due 2017 Held by KKR 3CareMore, Scripps Translational Science Institute, and Sentrian Launch Landmark Study of Remote Patient Monitoring for COPD Population 2CareMore, Scripps Translational Science Institute, and Sentrian Launch Landmark Study of Remote Patient Monitoring for COPD Population 3CareMore, Scripps Translational Science Institute, and Sentrian Launch Landmark Study of Remote Patient Monitoring for COPD Population 4CareMore, Scripps Translational Science Institute, and Sentrian Launch Landmark Study of Remote Patient Monitoring for COPD Population 5BioAmber Inc. Announces Pricing Of $35.1 Million Registered Offering 2BioAmber Inc. Announces Pricing Of $35.1 Million Registered Offering 3Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 2Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 3Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 4Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 5
... New Launches Should Contribute Significantly in Second Half, ... PRX ) today announced results for the,second quarter ended ... For the second quarter ended June 28, 2008, Par ... $20.1 million, or $0.60 per diluted,share. This is compared with ...
... ITMN ) today announced that Daniel G. Welch, ... Canaccord Adams 28th Annual,Global Growth Conference in Boston on ... access a live audio webcast of the presentation, investors ... relations page of InterMune,s,corporate website at http://www.intermune.com . ...
... YORK, Aug. 7 Microbes, Inc. today announced that ... all of its outstanding,Class B Common Stock Purchase Warrants, ... 2 until 12:00 midnight, New York City time, on,Friday, ... at 12:00,midnight, New York City time, on August 7, ...
Cached Biology Technology:Par Pharmaceutical Reports Second Quarter 2008 Results 2Par Pharmaceutical Reports Second Quarter 2008 Results 3Par Pharmaceutical Reports Second Quarter 2008 Results 4Par Pharmaceutical Reports Second Quarter 2008 Results 5Par Pharmaceutical Reports Second Quarter 2008 Results 6Par Pharmaceutical Reports Second Quarter 2008 Results 7Par Pharmaceutical Reports Second Quarter 2008 Results 8