Navigation Links
Scientists discover a genetic code for organizing DNA within the nucleus

DNA ?the long, thin molecule that carries our hereditary material ?is compressed around protein scaffolding in the cell nucleus into tiny spheres called nucleosomes. The bead-like nucleosomes are strung along the entire chromosome, which is itself folded and packaged to fit into the nucleus. What determines how, when and where a nucleosome will be positioned along the DNA sequence? Dr. Eran Segal and research student Yair Field of the Computer Science and Applied Mathematics Department at the Weizmann Institute of Science have succeeded, together with colleagues from Northwestern University in Chicago, in cracking the genetic code that sets the rules for where on the DNA strand the nucleosomes will be situated. Their findings appeared today in Nature.

The precise location of the nucleosomes along the DNA is known to play an important role in the cell's day to day function, since access to DNA wrapped in a nucleosome is blocked for many proteins, including those responsible for some of life's most basic processes. Among these barred proteins are factors that initiate DNA replication, transcription (the transfer of genetic information from DNA to RNA) and DNA repair. Thus, the positioning of nucleosomes defines the segments in which these processes can and can't take place. These limitations are considerable: Most of the DNA is packaged into nucleosomes. A single nucleosome contains about 150 genetic bases (the "letters" that make up a genetic sequence), while the free area between neighboring nucleosomes is only about 20 bases long. It is in these nucleosome-free regions that processes such as transcription can be initiated.

For many years, scientists have been unable to agree whether the placement of nucleosomes in live cells is controlled by the genetic sequence itself. Segal and his colleagues managed to prove that the DNA sequence indeed encodes "zoning" information on where to place nucleosomes. They also characterized this code and then, usin
'"/>

Source:American Committee for the Weizmann Institute of Science


Page: 1 2 3

Related biology news :

1. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
2. Scientists Replicate Hepatitis C Virus in Laboratory
3. Scientists detect probable genetic cause of some Parkinsons disease cases
4. Scientists find missing enzyme for tuberculosis iron scavenging pathway
5. Scientists seek answers on what activates deadly anthrax spores
6. Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
7. Scientists collaborate to assess health of global environment
8. Scientists decipher genome of fungus that can cause life-threatening infections
9. Scientists discover the cellular roots of graying hair
10. Scientists rid stem cell culture of key animal cells
11. Scientists develop new color-coded test for protein folding
Post Your Comments:
(Date:5/22/2015)... CT , May 22, 2015  NXT-ID, Inc. (NASDAQ: ... June 1st, it will be ending its promotional pricing and ... . Laurence Savin , Head of Marketing ... exclusive promotional pricing until the end of May. To get ... wocketwallet.com/invite and when we open the store on June 1, ...
(Date:5/20/2015)... May 20, 2015 NXT-ID, Inc. (NASDAQ: ... wholly owned subsidiary, 3D-ID LLC, a company engaged in ... for the biometrics technology portion of the recently awarded ... the Department of the Army. 3D-ID LLC ... for government, law enforcement and security agencies. ...
(Date:5/14/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/5whpxg/fingerprint ... Sensors Market in Smart Mobile Devices " report ... 2014 was a watershed year for fingerprint sensors in ... Pay,. Apple gave fingerprint sensors a raison d,etre in ... sensors are a must-have feature in flagship smartphones. ...
Breaking Biology News(10 mins):NXT-ID, Inc Announces Retail Price For Wocket Smart Wallet And Extends Discounted Promotional Price Till End Of May 2NXT-ID, Inc Announces Retail Price For Wocket Smart Wallet And Extends Discounted Promotional Price Till End Of May 3NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 2NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 3Global Smart Mobile Devices Fingerprint Sensors Market 2015-2019: Key Vendors are Authentec, Validity Sensors, Fingerprint Cards, Next Biometrics Group. IDEX, and Qualcomm 2
... Institutet have identified an important mechanism that regulates how ... cell. The study is published in the latest issue ... help us develop new drugs for things like neurological ... most organs of the body, old cells are continually ...
... To a tiny tadpole, life boils down to two basic ... The more a tadpole eats, the faster it grows big ... being active, which ups the odds of becoming someone else's ... activity levels in response to predation risk, but new research ...
... discovered how the brain creates a scent symphony from signals ... researchers found that nerve cells in the brain's olfactory bulb ... do not perceive complex scent mixtures as single objects, such ... cells, or neurons, detect the host of chemical compounds that ...
Cached Biology News:New stem-cell findings can help the body to cure itself 2Time of day tempers tadpoles' response to predators 2Researchers show how brain decodes complex smells 2
(Date:6/2/2015)... Calif. (PRWEB) June 02, 2015 ... build-to-order, independent blade-based and rackmount computing and storage ... announced the launch of its high density scale-out, ... Cirrascale Slipstream™ RM1622D . The high density, ... E3-1200 v4 product family with Intel® Iris™ Pro ...
(Date:6/2/2015)... GERMANTOWN, Md. , June 2, 2015 /PRNewswire/ ... a leader in synthetic biology, announced today the ... as Senior Vice President, Consumer Sector.  Mr. Jarry ... biologically-based solutions in products and applications for consumer ... Intrexon over 30 years of experience in leading ...
(Date:6/2/2015)... 2015 GOJO, inventors of PURELL ® ... stewardship at the White House Forum.  GOJO was among ... and stakeholders at the White House Forum to announce ... emergence of antibiotic-resistant bacteria, detect resistant strains, preserve the ... of resistant infections. "A primary prevention approach ...
(Date:6/1/2015)... York, NY (PRWEB) June 02, 2015 ... views on health care, Jack Uldrich has been ... firm in New York today. He will deliver ... , Uldrich has delivered presentations to the ... Academies of Audiology and Neurology, Alcetel-Lucent/Verizon Forum on ...
Breaking Biology Technology:Cirrascale® Announces Support for Intel® Xeon® Processor E3-1200 v4 Product Family; Launches Server Offering Optimized for Low Cost-per-Stream Transcoding Applications 2Cirrascale® Announces Support for Intel® Xeon® Processor E3-1200 v4 Product Family; Launches Server Offering Optimized for Low Cost-per-Stream Transcoding Applications 3Intrexon Announces New Sector Leader 2Intrexon Announces New Sector Leader 3GOJO Among Leaders At The White House Forum On Antibiotic Stewardship 2GOJO Among Leaders At The White House Forum On Antibiotic Stewardship 3GOJO Among Leaders At The White House Forum On Antibiotic Stewardship 4Futurist Jack Uldrich to Address the Future of Pharmaceuticals 2
... ... capacity, additional capabilities to growing laboratory in order to meet growing customer demands. , ... Tampa, FL (Vocus) June 15, 2009 ... triple the company,s previous capacity and will accommodate projected growth through 2015., , , , ...
... , ... Leadership in Highly Automated QT(sm) Evaluation and Helps Sponsors Avoid False Positives , ... Rochester, NY (PRWEB) June ... and automated QT analysis, announced that it has been chosen by a medium sized ...
... complete a $17.3 million Series C investment , , ... CEO , , - Aggressive launch of Sideguard(TM) Sidebranch ... - Expansion of management team, R&D and manufacturing capacity in ... June 15 Cappella, Inc. (Cappella) announces today ...
Cached Biology Technology:CoreRx, Inc. Announces Plans for Expansions to Meet the Needs of Growing Pharmaceutical Formulation Development Business 2iCardiac Selected for Multiple Cardiac Safety Studies 2Cappella Inc. Secures $17.3 Million Series C Investment 2Cappella Inc. Secures $17.3 Million Series C Investment 3Cappella Inc. Secures $17.3 Million Series C Investment 4Cappella Inc. Secures $17.3 Million Series C Investment 5
... White crystalline solid. HYGROSCOPIC. Water-soluble ... (Cat. No. 252005) but differing in the ... for the extraction of mycoplasma membrane antigens ... ≥98% by TLC. Soluble in H ...
Goat polyclonal to STMN2 ( Abpromise for all tested applications). Antigen: Synthetic peptide: AKTAMAYKEK, corresponding to C terminal amino acids 2-11 of STMN2. Entrez Gene ID: 11075 Swi...
Anti-Human alpha2-Antiplasmin Purified (Polyclonal) (goat IgG)...
... proud to work in collaboration with Pall ... syringe filters in a variety of membrane ... for use on the Caliper TPWII, MultiDose, ... Pricing for our Automation Certified Syringe Filters ...
Biology Products: