Navigation Links
Scientists develope a new model of artificial canine skin

Researchers at UNIVET, a spin-off of the Universitat Autònoma de Barcelona, in cooperation with the animal nutrition company Affinity Petcare, have developed an artificial cellular model which faithfully reproduces the characteristics of dog’s skin and which will allow, therefore, the carrying out of various lines of research related to skin biology and pathology without the need to use live animals.

The basic structure of skin consists of an external layer, the epidermis, and an internal layer, the dermis, separated by a basal membrane. A study of the interactions between the cell populations of the various layers is of vital importance for skin biology, but these interactions cannot be investigated adequately by means of conventional cell cultures.

Researchers at the UAB and UNIVET, in cooperation with Affinity Petcare, have developed an artificial canine skin model, very similar to normal skin, which is useful for research and which represents an alternative to the use of animals in research. The model allows the study of those illnesses which most often affect dogs?skin without the need to use animals.

To develop this model, cells from the epidermis (keratocytes) and the dermis (fibroblasts) from samples of healthy dogs were used. The dermis cells, inserted into a collagen marix (a very common protein in skin and joints), were used as a support for the epidermis cells, which were grown on its surface and were kept in growth conditions exposed to air. The cells proliferated forming the various layers of the epidermis.

The model develops a morphological structure similar to that of canine skin. Additionally, the expression of the dermis and epidermis proteins follows the same pattern of expression as that of normal canine skin, even forming a basal membrane, which also maintains the characteristics of conventional skin.
'"/>

Source:Universitat Autonoma de Barcelona


Page: 1

Related biology news :

1. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
2. Scientists Replicate Hepatitis C Virus in Laboratory
3. Scientists detect probable genetic cause of some Parkinsons disease cases
4. Scientists find missing enzyme for tuberculosis iron scavenging pathway
5. Scientists seek answers on what activates deadly anthrax spores
6. Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
7. Scientists collaborate to assess health of global environment
8. Scientists decipher genome of fungus that can cause life-threatening infections
9. Scientists discover the cellular roots of graying hair
10. Scientists rid stem cell culture of key animal cells
11. Scientists develop new color-coded test for protein folding
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Scientists develope new model artificial canine skin

(Date:8/29/2014)... as the prolific bloomer Emiliania huxleyi , can ... The finding contradicts the common view that E. ... scarce supplies of thiamine in the ocean to survive. ... the ocean," says CIFAR Senior Fellow Alexandra Worden ... with CIFAR fellows John Archibald (Dalhousie University), ...
(Date:8/29/2014)... of the Tibetan plateau -- the largest topographic anomaly ... both its profound effect on climate and its reflection ... GSA Bulletin , Katharine Huntington and colleagues employ a ... modern and fossil snail shells to investigate the uplift ... , Views range widely on the timing of surface ...
(Date:8/28/2014)... have identified a handful of bacterial culprits that may ... and ulcerative colitis, using patients, own intestinal immune responses ... 28 in the journal Cell . , Trillions ... plays a critical role in the development and progression ... number of bacterial species affect a person,s susceptibility to ...
Breaking Biology News(10 mins):Not all phytoplankton in the ocean need to take their vitamins 2Not all phytoplankton in the ocean need to take their vitamins 3Snails tell of the rise and fall of the Tibetan Plateau 2Snails tell of the rise and fall of the Tibetan Plateau 3Snails tell of the rise and fall of the Tibetan Plateau 4Snails tell of the rise and fall of the Tibetan Plateau 5Snails tell of the rise and fall of the Tibetan Plateau 6Snails tell of the rise and fall of the Tibetan Plateau 7Yale study identifies possible bacterial drivers of IBD 2
... embryonic stem cell, which has the potential to become any ... of genes, proteins that bind DNA, and molecules that modify ... from MIT and the University of California at San Francisco ... cells into mature heart cells. The study, the first to ...
... A team of researchers that has been working ... within four years of a near-commercial-scale production level., The ... has received a $2 million National Science Foundation grant ... Devarenne, a Texas A&M AgriLife Research biochemist and collaborator ...
... ultrasound waves, MIT engineers have found a way to ... drug delivery more efficient. This technology could pave the ... to the researchers. "This could be used for ... systemic drugs and proteins such as insulin, as ...
Cached Biology News:Probing matters of the heart 2Probing matters of the heart 3Oil from algae closer to reality through studies by unique collaboration of scientists 2Oil from algae closer to reality through studies by unique collaboration of scientists 3Getting (drugs) under your skin 2Getting (drugs) under your skin 3
(Date:8/28/2014)... BELLINGHAM, Washington, USA (PRWEB) August 27, 2014 ... Colorado next month for SPIE Laser Damage 2014 ... on optical materials for high-power lasers will run 14-17 ... international society for optics and photonics . , The ... key for understanding laser damage to optical materials will ...
(Date:8/28/2014)... 2014 Supplementing their complete line ... for Eppendorf Safe Lock Centrifuge Tubes . ... highest quality tubes at an affordable price. Eppendorf ... doing chemical, medical, pharmaceutical, and life science research ... regularly able to afford Eppendorf products. , Eppendorf ...
(Date:8/27/2014)... Rhythm, a biopharmaceutical company developing peptide therapeutics ... in metabolic disorders, announced today that it has filed ... Securities and Exchange Commission (SEC) relating to the proposed ... The number of shares to be offered and the ... determined. Citigroup and Cowen and Company will ...
(Date:8/27/2014)... survive impact by the huge amounts of energy ... energy for photosynthesis. The hypothesis is that the ... the energy throughout the entire protein molecule through ... now managed to successfully ,film, this process. , ... which play a role in photosynthesis and thus ...
Breaking Biology Technology:Laser Damage to Draw Researchers, Engineers, Scientists to 46th Annual Conference 2Laser Damage to Draw Researchers, Engineers, Scientists to 46th Annual Conference 3Eppendorf Safe Lock Centrifuge Tube Promotion Now Available at Major Pipette Distributor Pipette.com 2Eppendorf Safe Lock Centrifuge Tube Promotion Now Available at Major Pipette Distributor Pipette.com 3Rhythm Files Registration Statement for Proposed Initial Public Offering 2DTU researchers film protein quake for the first time 2
... talent and everywhere it is in chains. Fail to develop ... is 21st century wealth. This quotation is taken from Tony ... It opens chapter one of The Mismanagement of Talent (Oxford ... Anthony Hesketh, Phillip Brown and Sara Williams. , ,The ...
... My fathers slow retreat in the face of Alzheimers Disease was ... was slow, at first, but gathered momentum over time. Independence turned ... fine physical shape for a man of 80, but his memory ... or two was gone. His body simply forgot how to function. ...
... Wis. Four Wisconsin-based companies have be listed in Computerworlds ... , three of which landed within the top 25. Schneider ... Wisconsin company this year. American Family Insurance and ... 18th, respectively, and Lands End, Inc. came in ...
Cached Biology Technology:Talent Mismanagement 2Talent Mismanagement 3The passing of Ronald Reagan, and other Americans, is a reminder of the promise of stem-cell research 2
... Japan, also named Sendai virus) Envelope VECTOR ... molecules by means of membrane fusion. Most ... Oligo, cDNA, Antibodies, Vector, and Biomolecule ... has a high fusing capability in short ...
... Dithiothreitol DTT White ... Purity: ≥99% by titration. ... Absorbance: (100 mM, 280 ... EtOH or H 2 O. ...
... White solid.. PACKAGED UNDER INERT GAS. ... reaction is "driven" to completion. A protective agent ... found in many other preparations. Blocks the lethal ... by titration. Contaminants: Heavy metals: ≤1 ...
... Faster speeds, highest precision, more ... flexible concept: this is the definition of ... few years nucleic acid research has been ... capabilities required of PCR Systems. To ...
Biology Products: