Navigation Links
Scientists determine structure of enzyme that disrupts bacterial virulence

-sensing.

"Being able to disrupt quorum-sensing in these organisms could potentially augment our current treatments, and knowing the structure of this quorum-quenching enzyme will greatly help in developing more effective enzymes for this type of application," explained Walter Fast, assistant professor in the College of Pharmacy at the University of Texas at Austin.

In addition to treating plant pathogens, the hope is that these quorum-quenching enzymes may eventually be developed for use in treating human and animal pathogens that also rely on quorum-sensing for their virulence.

For example, bacterial pathogens such as Burkholderia mallei, which is responsible for the biowarfare threat glanders, and Pseudomonas aeruginosa, which often forms opportunistic infections on the lung surfaces of patients with cystic fibrosis, rely on their quorum-sensing systems to increase their pathogenicity and resistance to antibiotics.


'"/>

Source:Brandeis University


Page: 1 2

Related biology news :

1. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
2. Scientists Replicate Hepatitis C Virus in Laboratory
3. Scientists detect probable genetic cause of some Parkinsons disease cases
4. Scientists find missing enzyme for tuberculosis iron scavenging pathway
5. Scientists seek answers on what activates deadly anthrax spores
6. Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
7. Scientists collaborate to assess health of global environment
8. Scientists decipher genome of fungus that can cause life-threatening infections
9. Scientists discover the cellular roots of graying hair
10. Scientists rid stem cell culture of key animal cells
11. Scientists develop new color-coded test for protein folding

Post Your Comments:
(Date:11/24/2009)...dge, Md. (November 24, 2009) New research on bact...r ecosystems reveals predictable temporal patterns...nities as markers for monitoring climate change in... in the Proceedings of the National Academy of Sc...ities in the six rivers shifted synchronously over...
(Date:11/23/2009)...gton, D.C. The community-associated strain of the... resistant to most common antibioticsposes a far g...making its way into hospitals, according to a stud...seases . , The new threat is easily picked up i...s and has increased the overall burden of MRSA wit...
(Date:11/23/2009)...w study by the Wildlife Conservation Society says ...amp in the Republic of Congopart of the "mother lo...yearare becoming increasingly threatened by growin...ommends protection of the swamp forests adjacent t... after recent surveys confirmed that high densitie...
Breaking Biology News(10 mins):Researchers establish common seasonal pattern among bacterial communities in Arctic rivers 2New study finds MRSA on the rise in hospital outpatients 2A year after discovery, Congo's 'mother lode' of gorillas remains vulnerable 2Delirium in hospitalized adults 3A Situation critical no relief available 50777 1Delirium in hospitalized adults 3A Situation critical no relief available 50777 2Elderly breast cancer patients receive chemotherapy if treated in private practices 50775 1Elderly breast cancer patients receive chemotherapy if treated in private practices 50775 2Elderly breast cancer patients receive chemotherapy if treated in private practices 50775 3New Pre Clinical Data on OmniGuides BeamPath NEURO 28TM 29 Demonstrates Precise Cutting in Brain Tissue 12900 1New Pre Clinical Data on OmniGuides BeamPath NEURO 28TM 29 Demonstrates Precise Cutting in Brain Tissue 12900 2New Pre Clinical Data on OmniGuides BeamPath NEURO 28TM 29 Demonstrates Precise Cutting in Brain Tissue 12900 3
...an exceptional ability to spray venom into eyes of...ysiological and Biochemical Zoology reveals how t...target. , The name "spitting cobra" is a bit of a...s the study,s lead author Bruce Young, director of...ysical Therapy at the University of Massachusetts,...
...uary 22, 2009--Biotechnology companies are buildin...chniques over the past decade and are expected to ...rs, reports Genetic Engineering and Biotechnology...logy offers a number of advantages, including redu...lytical performance, multiparameter testing, and u...
...A patented Michigan State University process to pr...nol means extra nutrients don,t have to be added, .... , The AFEX (ammonia fiber expansion) pretreatme...stinguished Professor of chemical engineering and ...own of cellulose and hemicellulose in plants 75 pe...
Other Biology News:Here's venom in your eye: Spitting cobras hit their mark 2GEN reports on growing reliance on microfluidics technology 2Process can cut the cost of making cellulosic biofuels 2
(Date:11/25/2009)...ire-FirstCall/--ArdeaBiosciences,Inc.(Nasdaq: RDEA...tandchiefexecutiveofficer,willpresentatthePiperJaf...ondetailsareasfollows:,PiperJaffray21stAnnualHeal...2:00p.m.EasternTime,Location:TheNewYorkPalaceHotel...r.net/ireye/,target=,_blank,title=,http://www.cor...
(Date:11/24/2009)...re-FirstCall/--IES(Nasdaq: IESC ),aleadingnational...vicesforthecommercial,industrialandresidentialmark...sbeenawardedacontractfromManhattanTorconJVtoinstal...-4)replacementfacilityattheU.S.ArmyMedicalResearch...ckinFrederick,Md. ,, ThenewUSAMRIIDreplacementf...
(Date:11/24/2009)...ew York investment bank KTA Capital,s client Neure....7 mil convertible note private placement with a U...was arranged by KTA Capital as Neuren,s exclusive ... New York (PRWEB) November 23, 2009 -- The in...C ("KTA Capital") has announced that its...
(Date:11/24/2009)...rio,Nov.24/PRNewswire-FirstCall/--DowAgroSciencesC...eeds,adivisionofThompsonsLimitedofBlenheim,Ontario...ciences,currentseedsbusinessasthecompanyanticipate...groSciencesHerbicideTolerantTraitTechnologyincorni...re. ,, "Thisacquisitionbringstogethertwostrongp...
Breaking Biology Technology:Ardea Biosciences to Present at the Piper Jaffray 21st Annual Health Care Conference 2Integrated Electrical Services Awarded Contract to Provide Electrical Systems for U.S. Army Medical Research Institute of Infectious Diseases 2KTA Capital Arranges an AU$6.7 Million Private Placement by Neuren Pharmaceuticals 2Dow AgroSciences Canada Announces Agreement to Acquire Hyland Seeds 2Dow AgroSciences Canada Announces Agreement to Acquire Hyland Seeds 3
...Inc. (Nasdaq: VIAP ), a biotechnology company fo...tment of cardiovascular and metabolic disease, tod...March 31, 2009, from the staff of the NASDAQ Stock...rently comply with NASDAQ Marketplace Rule 4310(c)...companies maintain either: (i) $2,500,000 in stock...
... for PACS data disaster recovery , , CHICAGO, Apr...siness unit of Siemens Healthcare ( www.sieme... www.harris.com ) are joining forces to offer h...for Picture Archiving and Communication Systems (P...ity. , , (Logo: http://www.newscom.com/cgi-b...
...all/ -- China Agri-Business, Inc.,(OTC Bulletin Bo...ral,application products through its operating com... the year ended December 31,2008. , Revenue fo...385, a,decrease of 3.8% as compared to $3,037,414 ... operations were adversely affected by natural and...
Other Biology Technology:VIA Pharmaceuticals Receives Anticipated Notice From NASDAQ 2VIA Pharmaceuticals Receives Anticipated Notice From NASDAQ 3VIA Pharmaceuticals Receives Anticipated Notice From NASDAQ 4Siemens Healthcare Announces Planned Collaboration with Harris Corporation 2Siemens Healthcare Announces Planned Collaboration with Harris Corporation 3Siemens Healthcare Announces Planned Collaboration with Harris Corporation 4China Agri-Business Announces 2008 Operating Results 2China Agri-Business Announces 2008 Operating Results 3China Agri-Business Announces 2008 Operating Results 4China Agri-Business Announces 2008 Operating Results 5
Rabbit Anti-Human EDG-1CT (endothelial cell differentiation gene-1, C terminal) Polyclonal Antibody, Unconjugated from Exalpha Biologicals, Inc.
Mouse Anti-Myosin, light chain 1, cardiac Monoclonal Antibody, Unconjugated, Clone MLM544 from Abcam
...orylated Anti-GluR1 Glutamate is the main excitat...it had been considered to act only on the ligand-g...te receptors that are involved in the fast excitat... been shown to regulate enzymes producing second m...
Armenian Hamster Anti-Mouse CD48 Monoclonal Antibody, Biotin Conjugated, Clone HM48-1 from BioLegend
Biology Products: