Navigation Links
Scientists detect probable genetic cause of some Parkinson's disease cases

Two new studies strongly suggest that a mutation in a recently discovered gene is the most common genetic cause of Parkinson's disease identified to date. The discovery by an international research team provides fresh evidence that genetics may contribute to the development of some cases of Parkinson's disease. The findings could lead to the development of a genetic test to detect the mutation in individuals at risk. The research team includes investigators at the National Institute on Aging (NIA) and scientists supported by the National Institute of Neurological Disorders and Stroke (NINDS).

Parkinson's disease, which affects at least 500,000 Americans, is a progressive neurologic disorder that is caused by the degeneration of nerve cells in the portion of the brain that controls movement. Scientists have long suspected genetics plays a role in the onset of the disease. In these studies, the investigators found that a mutation in the gene LRRK2 appears to occur in at least one of every 60 people who have the disease. Overall, the mutation could be responsible for up to 5 percent of Parkinson's disease in people with a family history of the disorder and may account for 1½ to 2 percent of cases in individuals who do not have a family history of the disease. The researchers found a mutation in one copy of the gene can lead to the disease. The findings were published online by Lancet at 6:30 p.m. ET on January 17, 2004. Copies of the studies will be made available to the media on January 17. To request copies, journalists should email pressoffice@lancet.com. "Among the forms of Parkinson's disease that are genetic in origin, this gene mutation causes more cases of Parkinson's disease than any other gene discovered to date," says Andrew Singleton, Ph.D., chief of the Molecular Genetics Unit in the NIA's Laboratory of Neurogenetics. "Knowing that this mutation is not only important in familial forms of disease, but in typical sporadic disease, where there is no st
'"/>

Source:Eurekalert


Page: 1 2 3

Related biology news :

1. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
2. Scientists Replicate Hepatitis C Virus in Laboratory
3. Scientists find missing enzyme for tuberculosis iron scavenging pathway
4. Scientists seek answers on what activates deadly anthrax spores
5. Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
6. Scientists collaborate to assess health of global environment
7. Scientists decipher genome of fungus that can cause life-threatening infections
8. Scientists discover the cellular roots of graying hair
9. Scientists rid stem cell culture of key animal cells
10. Scientists develop new color-coded test for protein folding
11. Scientists identify genetic pathways essential to RNA interference
Post Your Comments:
(Date:7/31/2014)... Spain, France, and the U.S. has discovered and ... definitive member of the tribe Omaliini that has ... description were made possible through the use of ... allows the detailed study of otherwise invisible specimens ... in the journal Annals of the Entomological ...
(Date:7/31/2014)... photovoltaic effect in 1839, humankind has sought to further ... own purposes. In a new research report published in ... Journal , scientists may have uncovered a new ... on a naturally occurring combination of lipids that have ... time and across speciessuggests that this specific natural combination ...
(Date:7/31/2014)... Hibiscus flowers- they are an iconic symbol of ... in the landscape. Some, like Hawaii,s State Flower- ... Only a relatively few botanists and Hawaiian conservation ... and intriguing related group of plants known as ... Brother of Hibiscus species are in fact highly ...
Breaking Biology News(10 mins):Scientists shine bright new light on how living things capture energy from the sun 2Brother of Hibiscus is found alive and well on Maui 2
... millions the number of poor forced to seek new ... intense dust storms plaguing many areas menace the health ... a new report. , Thick storms rising out of ... Japan and even reduce air quality over North America, ...
... nerve cells to trees -- some are short and bushy ... branches coming out of one or two main trunks. Different ... to discover how these dissimilar patterns come about and why. ... Rutgers, The State University of New Jersey, examines the role ...
... today that regions of the human genome have been ... specific time-points during evolution. It appears that long periods ... accretion of duplicated DNA fragments, are "punctuated" by relatively ... time that such temporal bias has been documented for ...
Cached Biology News:Millennium Ecosystem Assessment: Many of 2 billion dryland dwellers at risk as land degrades 2Millennium Ecosystem Assessment: Many of 2 billion dryland dwellers at risk as land degrades 3Millennium Ecosystem Assessment: Many of 2 billion dryland dwellers at risk as land degrades 4Snapin: A protein with therapy potential for autism 2'Punctuated' evolution in the human genome 2'Punctuated' evolution in the human genome 3
(Date:7/31/2014)... July 31, 2014 CollabRx, Inc. (NASDAQ: ... therapeutic decision-making in oncology, today announced that it will ... to discuss the Company's financial results for the first ... about the business in the current fiscal year. , ... on Thursday, August 14, 2014, at 5 p.m. EDT ...
(Date:7/31/2014)... Diego, CA (PRWEB) July 31, 2014 ... announced today the integration of Omicsoft’s Array Suite with ... both platforms will be able to send data in ... integration works with all versions of tranSMART including the ... the art statistics, visualization and storage for the analysis ...
(Date:7/31/2014)... SoundConnect , an award ... proud to announce the addition of Adobe Connects ... elearning tools to quickly deploy and manage online ... tools for desktop and mobile learning solutions. , ... perfect online training solution, enabling organizations to deploy, ...
(Date:7/30/2014)... PARIS , July 30, 2014  Regeneron ... NYSE: SNY) today announced that the Companies intend to ... pediatric disease priority review voucher in connection with the ... review voucher entitles the holder to designate a BLA ... review from the filing date instead of the standard ...
Breaking Biology Technology:CollabRx, Inc. Schedules First Quarter Fiscal Year 2015 Financial Conference Call and Business Update 2Rancho BioSciences, in Partnership with Omicsoft, have Integrated Array Suite with tranSMART 2Rancho BioSciences, in Partnership with Omicsoft, have Integrated Array Suite with tranSMART 3SoundConnect Enhances Portfolio with Adobe Connect Learning Management System (LMS) 2Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 2Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 3Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 4Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 5Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 6
... Ohio Scientists are using the engineering technology ... design 3-D models for the replacement of delicate ... or trauma. The researchers, combining engineering ... technique called topological optimization to design an experimental ...
... - Ocean Nutrition Canada (ONC) supplier of the most trusted source ... acquisition of the exclusive global marketing and distribution rights to GAT ... , , ... acquired the rights to exclusive use of GAT,s unique and patented ...
... NEW YORK , July 12 ... or the "Company"), an international,biopharmaceutical company with operations in ... has been awarded a $700,000 contract from ... Advanced Technology,Research Center (USAMRMC-TATRC) under U.S. Army Medical Research ...
Cached Biology Technology:High-performance engineering used to design facial bone replacements 2High-performance engineering used to design facial bone replacements 3Ocean Nutrition Canada Announces Acquisition of Exclusive License to GAT Food Essentials, Omega-3 Microencapsulation-Emulsion Technology 2Ocean Nutrition Canada Announces Acquisition of Exclusive License to GAT Food Essentials, Omega-3 Microencapsulation-Emulsion Technology 3NeoStem to Receive $700,000 from the U.S. Army's Medical Research and Materiel Command to Advance Adult Stem Cell Therapies in Treating Traumatic Wounds 2NeoStem to Receive $700,000 from the U.S. Army's Medical Research and Materiel Command to Advance Adult Stem Cell Therapies in Treating Traumatic Wounds 3NeoStem to Receive $700,000 from the U.S. Army's Medical Research and Materiel Command to Advance Adult Stem Cell Therapies in Treating Traumatic Wounds 4NeoStem to Receive $700,000 from the U.S. Army's Medical Research and Materiel Command to Advance Adult Stem Cell Therapies in Treating Traumatic Wounds 5
... Colorimetric Detection System is intended for use ... generated by an in-house validated in vitro ... of interest. • ... a hybridization capture assay designed to detect ...
... is optimized for maximum packaging efficiencies of cDNA ... l vector. Using a test insert with Novagen's ... (> 4 x 10^8 pfu/g ligated l control ... extremely easy to use; simply add up to ...
BD BioCoat Laminin 150 mm Culture Dishes...
MAb to Desmoplakin I & II Desmoplakin I & II...
Biology Products: