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Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

anufacture more cholesterol, which it does in the form of very low-density lipoproteins. The investigators noted that in mice fed high-fat diets, the PCG-1beta mechanism actually decreased cholesterol in the liver while increasing it in the bloodstream.

"Before this report, it wasn't clear what the differences were between saturated fats and unsaturated fats in their ability to raise cholesterol blood levels," commented Jeffrey Flier, MD, an obesity specialist at Beth Israel Deaconess Medical Center. "These are important findings in a long-established area of medicine."


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Source:Dana-Farber Cancer Institute


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Rabbit monoclonal [EP282Y] to Asparagine synthetase ( Abpromise for all tested applications). Antigen: Synthetic peptide corresponding to residues in the C-terminus of Human Asparagine synthetas
Dog polyclonal to Porcine Pancreatic Islets of Langerhans Cells ( Abpromise for all tested applications). Antigen: Tissue / cell preparation (Pig): Sonicated crude membrane fraction of porcine p
Transcription factor Sp2. [Source:Uniprot/SWISSPROT;Acc:Q02086] Antigen: Recombinant Protein Epitope Signature Tag (PrEST).
E2F2 protein
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