Navigation Links
Salk scientists get to the root of plant cell fate

nches, and flowers. "We want to know how a plant can set aside a root and a shoot pole during embryogenesis and keep these functions separate," Long says.

The researchers found that the TOPLESS gene encodes a protein (TOPLESS) that is a transcriptional co-repressor. In plants and animals, co-repressors regulate gene expression by inhibiting the activity of transcription factors, which act as switches to activate target genes. Transcription factors control gene activity by binding to DNA sequences adjacent to a gene, but they are deactivated when they recruit and interact with co-repressors.

Long explains that the normal function of TOPLESS protein is to silence genes required for root development in the top or shoot half of a plant embryo. "In plants with a mutant TOPLESS, genes that should be kept off in order to produce a shoot aren't, so a root is produced," he explains.

Since transcriptional repression plays such a key role in animal embryonic development, the finding that a co-repressor controls polarity in plants was surprising, says Long. "We thought that because plants and animals are believed to have largely developed independently from each other, they would have used a different set of processes to maintain polarity," he says. "But they have a very similar toolbox of genes to set up some aspects of their body plan."

However, a critical difference between plants and animals in terms of polarity development is how much more tolerant plants are of manipulation. Long says, "In animals, early cell divisions are very important to development of polarity and if something goes awry with co-repressors, the animal quickly dies. But in plants, polarity can be changed much later in embryogenesis."

"Plants are so plastic. Our topless mutants can survive very well," he continues. "This suggests that the actual polarity in the embryo isn't fixed until late in development, and that offers us an opportunity to change the fate of the
'"/>

Source:Salk Institute


Page: 1 2 3

Related biology news :

1. Wisconsin scientists grow critical nerve cells
2. UCSB scientists probe sea floor venting to gain understanding of early life on Earth
3. UAB scientists discover the origin of a mysterious physical force
4. Fox Chase Cancer Center scientists identify immune-system mutation
5. Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.
6. U-M scientists find genes that control growth of common skin cancer
7. UCLA scientists transform HIV into cancer-seeking missile
8. RNA project to create language for scientists worldwide
9. Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals
10. To control germs, scientists deploy tiny agents provocateurs
11. Leprosy microbes lead scientists to immune discovery
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Salk scientists get the root plant cell fate

(Date:4/23/2014)... is a technique used to read quickly. It ... skipping non-essential words and/ or sentences. Similarly to ... to quickly "read" genetic information. Genes that need ... the smaller the encoding message, the easier it ... from Instituto Gulbenkian de Cincia (IGC, Portugal) and ...
(Date:4/22/2014)... 2014) -- There are all sorts of signaling strategies ... their colorful tails; satin bowbirds build specialized stick structures, ... objects; and European bitterling males show off bright nuptial ... unique method to communicate with others. , ... can have profound fitness implications for individuals that are ...
(Date:4/22/2014)... 22, 2014) Biotechnology scientists must be aware of ... and licensing guidelines, according to a new paper from ... in the current issue of the journal Regenerative ... 2013 U.S. Supreme Court ruling in the case Association ... occurring genes are unpatentable. The court case and rulings ...
Breaking Biology News(10 mins):Cell division speed influences gene architecture 2Best practices in communication for the animal world 2Best practices in communication for the animal world 3New patenting guidelines are needed for biotechnology 2New patenting guidelines are needed for biotechnology 3
... 2013 Medbox, Inc. (OTC Markets: MDBX) ( www.medboxinc.com ), ... the medical and retail industries, announced that their patented software ... means to meet the priorities spelled out by the US ... United States Attorneys titled, "Guidance Regarding Marijuana ...
... flatworms have the remarkable ability to regrow any missing body ... the molecular basis of regeneration. Over the ... differ depending on the severity of the injury they suffer. ... wound reacts at the cellular and molecular levels quite differently ...
... to the origin of species as "that mystery of mysteries," ... cannot fully explain how new animals and plants arise. ... based on the assumption that the main cause of the ... formation of barriers to reproduction between populations. Those barriers ...
Cached Biology News:Medbox's Marijuana Dispensing System Assists Operators in Complying with Federal Government's New Canna-Business Guidelines 2Medbox's Marijuana Dispensing System Assists Operators in Complying with Federal Government's New Canna-Business Guidelines 3Tissue loss triggers regeneration in planarian flatworms 2Long-held assumption about emergence of new species questioned 2Long-held assumption about emergence of new species questioned 3
(Date:1/15/2014)... TAIPEI , Jan. 15, 2014 TaiGen Biotechnology ... an exclusive agreement with R-Pharm, a leading Russian pharmaceutical ... in the Russian Federation , ... Commonwealth Independent States (CIS). Nemonoxacin is a novel antibiotic for ...
(Date:1/14/2014)... 14, 2014 Carahsoft and CDS Federal ... 23, 2014 at 2pm EST (11am PST), “Natural Language ... focuses on how technology can turn raw, heterogeneous data ... government agencies. The online webinar will last approximately one ...
(Date:1/14/2014)... 2014  3D Communications, a leading provider of strategic communications services to ... events in the United States and ... Cox , JD, is returning to the firm,s Washington, ... 3D after more than two years of service as Associate Commissioner ...
(Date:1/14/2014)... January 14, 2014 EquitiesIQ, a leading ... (OTCQB: ALQA). Alliqua is an emerging biomedical company acquiring, ... wound care market. , Free report download: http://equitiesiq.com/reports/alliqua/ ... a seasoned management team and Board, which launched the ...
Breaking Biology Technology:TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2Former FDA Associate Commissioner Returns To 3D Communications 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3
... England, February 14 Executives from Senexis,and O2H, ... under which,O2H will provide synthetic and computational chemistry ... an FTE basis., "We believe our collaboration ... and will benefit our search for new,therapeutics to ...
... Feb. 14 AspenBio Pharma,Inc. (Nasdaq: APPY ) ... drugs and diagnostics for animals and humans, has been,invited ... Growth Stock,Conference. The conference will be held February 18-21, ... California., Roth Capital Partners Stock Conferences are one ...
... Onyx,Pharmaceuticals, Inc. (Nasdaq: ONXX ) today announced that ... quarter and full year 2007,financial results and provide a ... Eastern Time (2:00 p.m. Pacific Time). Financial results,for the ... be released,earlier that day., Interested parties may access ...
Cached Biology Technology:Senexis and O2H (Oxygen Healthcare) Announce Medicinal Chemistry Collaboration 2AspenBio Pharma to Present at the Roth Capital Partners 20th Annual Growth Stock Conference 2Onyx Pharmaceuticals Announces Fourth Quarter and Full Year 2007 Financial Results Teleconference and Webcast 2
Vented Caps for 75 cm2 Flasks...
BD BioCoat Poly-D-Lysine 60 mm Culture Dishes, tissue-culture treated polystyrene with a uniform application of poly-D-lysine....
BD BioCoat Laminin 60 mm Culture Dishes, tissue-culture treated polystyrene with a uniform application of mouse laminin....
... Ciphergens ProteinChip System, Series 4000 incorporates ... clinical researchers and biologists in biomarker research. ... the fastest route for converting biomarker discoveries ... platform. The Series 4000 is designed to ...
Biology Products: