Navigation Links
Salk scientists get to the root of plant cell fate

nches, and flowers. "We want to know how a plant can set aside a root and a shoot pole during embryogenesis and keep these functions separate," Long says.

The researchers found that the TOPLESS gene encodes a protein (TOPLESS) that is a transcriptional co-repressor. In plants and animals, co-repressors regulate gene expression by inhibiting the activity of transcription factors, which act as switches to activate target genes. Transcription factors control gene activity by binding to DNA sequences adjacent to a gene, but they are deactivated when they recruit and interact with co-repressors.

Long explains that the normal function of TOPLESS protein is to silence genes required for root development in the top or shoot half of a plant embryo. "In plants with a mutant TOPLESS, genes that should be kept off in order to produce a shoot aren't, so a root is produced," he explains.

Since transcriptional repression plays such a key role in animal embryonic development, the finding that a co-repressor controls polarity in plants was surprising, says Long. "We thought that because plants and animals are believed to have largely developed independently from each other, they would have used a different set of processes to maintain polarity," he says. "But they have a very similar toolbox of genes to set up some aspects of their body plan."

However, a critical difference between plants and animals in terms of polarity development is how much more tolerant plants are of manipulation. Long says, "In animals, early cell divisions are very important to development of polarity and if something goes awry with co-repressors, the animal quickly dies. But in plants, polarity can be changed much later in embryogenesis."

"Plants are so plastic. Our topless mutants can survive very well," he continues. "This suggests that the actual polarity in the embryo isn't fixed until late in development, and that offers us an opportunity to change the fate of the
'"/>

Source:Salk Institute


Page: 1 2 3

Related biology news :

1. Wisconsin scientists grow critical nerve cells
2. UCSB scientists probe sea floor venting to gain understanding of early life on Earth
3. UAB scientists discover the origin of a mysterious physical force
4. Fox Chase Cancer Center scientists identify immune-system mutation
5. Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.
6. U-M scientists find genes that control growth of common skin cancer
7. UCLA scientists transform HIV into cancer-seeking missile
8. RNA project to create language for scientists worldwide
9. Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals
10. To control germs, scientists deploy tiny agents provocateurs
11. Leprosy microbes lead scientists to immune discovery
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Salk scientists get the root plant cell fate

(Date:8/29/2014)... at UC Davis have made some surprising discoveries ... Studying simian immunodeficiency virus (SIV), the team found ... cells are early responders to viral invasion and ... a cytokine called interleukin-1 beta (IL-1β). , ... causes breakdown of the gut epithelium that provides ...
(Date:8/29/2014)... about what genetic changes transform wild animals into domesticated ... is a University of Montana assistant professor, has made ... of the brain and the nervous system were particularly ... 28 in Science and gives answers to ... ., The domestication of animals and plants, a prerequisite ...
(Date:8/29/2014)... understand how the repeated climatic shifts over the ... of genetic diversity, a team of researchers led ... Ana Carnaval developed a new biodiversity metric called ... which the genetic variation within species is restricted ... professor of biology, and 14 other researchers from ...
Breaking Biology News(10 mins):The early cost of HIV 2New research reveals how wild rabbits were genetically transformed into tame rabbits 2New research reveals how wild rabbits were genetically transformed into tame rabbits 3CCNY team defines new biodiversity metric 2
... proteins are the bad guys that help bacterial pathogens do ... immune system. In essence, they knock down the front ... Now, researchers at the University of California, San Diego (UCSD) ... an effector protein called YpkA, one of several effectors of ...
... could soon be roaming our pastures, reports Cath O’Driscoll in ... in New Zealand have discovered that some cows have genes ... and plan to use this information to breed herds of ... plan to breed commercial herds producing milk with the unique ...
... H5N1 strain of avian influenza may hold the key to ... of researchers. In a study published today in the open ... antibodies taken from avian flu survivors in Vietnam can be ... virus in culture vitro and in mice. , The H5N1 ...
Cached Biology News:How plague-causing bacteria disarm host defense 2Skimmed milk -- Straight from the cow 2Avian influenza survivors' antibodies effective at neutralising H5N1 strain 2
(Date:9/2/2014)... Victoria, Australia (PRWEB) September 02, 2014 ... provide a cure for chronic tinnitus are seeking support ... run on the Indiegogo platform ( http://igg.me/at/tinaway ), was ... to be a therapeutic ‘mHealth’ app and is based ... brainchild of a team of biomedical and software engineers, ...
(Date:8/31/2014)... -- Wockhardt Limited today announces a major boost to ... two of its drugs, WCK 771 and WCK 2349, ... from U.S. Food & Drug Administration (FDA).  QIDP status ... have a high degree of unmet need in their ... (a top U.S. government health and safety body).  QIDP ...
(Date:8/30/2014)... Dallas, TX (PRWEB) August 31, 2014 ... Industry is a professional and in-depth study on ... industry in Global and China. , The report ... definitions, applications and industry chain structure. Global market ... with a focus on history, developments, trends and ...
(Date:8/29/2014)... August 29, 2014 According to a new ... the global orthobiologics market was valued at USD 3,754.6 million ... USD 5,519.9million in 2019at a CAGR of 5.9% from 2013 ... years and above is afflicted by bone and joint disorders, ... year 2020. This has and will continue to increase the ...
Breaking Biology Technology:tinAway Pty. Ltd. launch a crowdfunding campaign to fund a clinical trial of tinAway, a new potential cure for chronic tinnitus 2tinAway Pty. Ltd. launch a crowdfunding campaign to fund a clinical trial of tinAway, a new potential cure for chronic tinnitus 3tinAway Pty. Ltd. launch a crowdfunding campaign to fund a clinical trial of tinAway, a new potential cure for chronic tinnitus 4tinAway Pty. Ltd. launch a crowdfunding campaign to fund a clinical trial of tinAway, a new potential cure for chronic tinnitus 5U.S. FDA Grants QIDP Status for Wockhardt Anti-Infective Drug Discovery Program 2U.S. FDA Grants QIDP Status for Wockhardt Anti-Infective Drug Discovery Program 3Electrical Insulating Varnish Market World, China Regional Analysis & 2020 Forecasts Available at DeepResearchReports.com 2Electrical Insulating Varnish Market World, China Regional Analysis & 2020 Forecasts Available at DeepResearchReports.com 3Global Orthobiologics Market to Reach $5,519.9 Million by 2019: Transparency Market Research 2Global Orthobiologics Market to Reach $5,519.9 Million by 2019: Transparency Market Research 3
... , CAMBRIDGE, Mass., Aug. 11 Tolerx, ... therapies for immune-mediated diseases, today announced changes to the protocol for its ... of otelixizumab, a targeted T cell immunomodulator, in patients with new-onset autoimmune ... urable Response Therapy E valuation F or E arly ...
... WALTHAM, Mass., Aug. 11 Decision Resources, one of the world,s ... that the entry and uptake of premium-priced biologics will drive the ... $420 million in 2008 to nearly $2 billion in 2018. , ... Lupus Erythematosus finds that the primary drivers of market growth ...
... , , ... that BD Biosciences, a segment of BD (Becton, Dickinson and ... Pathway Navigation technologies into its new website. By leveraging ... its research customers to quickly and easily identify products and ...
Cached Biology Technology:Tolerx Announces Amendment to Phase 3 DEFEND Protocol 2Tolerx Announces Amendment to Phase 3 DEFEND Protocol 3Biologic Agents Will Drive the Systemic Lupus Erythematosus Drug Market to More Than Quadruple to Nearly $2 Billion in 2018 2Ingenuity's Technology Powers BD Cell Pathways Tool on New BD Biosciences Website 2
Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
... Quality ISO 9001:2000 Certified ... All Precedures Validated, SOP's Training ... Process for All Procedures GLP Documentation Upon ... one stop shopping point for all your ...
Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
Request Info...
Biology Products: