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Rutgers researchers find fat gene

, with similar results.

The researchers showed that the enzyme encoded by the PAH1 gene looks and acts very much like the lipin found in mammals. The yeast PAP enzyme shares a high resemblance to the lipin protein in mammals so they logically deduced the link between PAP enzyme function and lipin.

"These findings are of major importance to the AIDS community as well as to those concerned with the obesity epidemic," said Jean Chin, a program director at the National Institute of General Medical Sciences (NIGMS), the part of the National Institutes of Health that funded the research. Carman's research is also supported by the New Jersey Agricultural Experiment Station.

Obesity in the United States has risen at an epidemic rate during the past 20 years, a condition affecting about one-third of American adults, according to the Centers for Disease Control and Prevention. One of the national health objectives for the year 2010 is to reduce the prevalence of obesity among adults to less than 15 percent.


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Source:Rutgers, the State University of New Jersey


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