Navigation Links
Role of noise in neurons

Addressing a current issue in neuroscience, Aldo Faisal and Simon Laughlin from Cambridge University investigate the reliability of thin axons for transmitting information. They show that noise effects in ion channels in the brain are much larger than previously assumed ?meaning the fidelity of transmission is compromised.

Neurons in the cerebral cortex of the brain can have a wiring density of up to 4km per mm3 by using incredibly thin axons as wires, with an average diameter of 0.3 micrometers (1ìm is one millionth of a meter). Although, as in computer chips, this miniaturization economizes on space and energy, it increases the noise introduced by thermodynamic fluctuations in a neuron's voltage-gated ion channels. Axons use action potential (AP) to transmit information fast and reliably to synapses, but the reliability of transmissions down fibers of less than 0.5 ìm in diameter was unknown until this paper.

Using detailed models of rodent and squid axons and stochastic simulations, the authors performed experiments, now published in PLoS Computational Biology, which took several months to simulate a few milliseconds of real time in the brain. They show how conduction along such thin axons is affected by the probabilistic nature of voltage-gated ion channels (channel noise). Channel noise destroys information in the AP, and they conclude that these effects are much larger than previously supposed and therefore must be taken into account in any future studies of neural coding and the reliability of synaptic transmission.


'"/>

Source:Public Library of Science


Page: 1

Related biology news :

1. Elephants imitate truck noises, other animals
2. Researchers quantify more noise in gene expression
3. Phenotype is influenced by nature, nurture and noise
4. New dyslexia theory blames noise
5. Mysterious neural noise actually primes brain for peak performance
6. Cells use noise to make cell-fate decisions
7. Dinosaur hearing, listening to muscle noise, quieter cubicles
8. Eating, body weight regulated by specific neurons
9. Growth factor-promoting angiogenesis expressed in tumor cells and normal neurons
10. Nanowire arrays can detect signals along individual neurons
11. Parkinsons mutation stunts neurons
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Role noise neurons

(Date:12/3/2014)... , Dec. 2, 2014 As part of ... Inception Technologies is pleased to announce the release of ... customers to collect the workforce data that they need. ... have been left by existing readers. Many such devices ... connectivity and modern technology. Older models force users to ...
(Date:11/21/2014)... YORK , Nov. 19, 2014  Earlier this ... at New York College, and one of the most ... biosensor signals that are transmitted from Smartphones to third ... were Smartphones and has one of the earliest known ... discussing its usage in the military, child care, elder ...
(Date:11/21/2014)... -- C-Labs LLC, a leading provider of remote and ... announced the appointment of John Traynor to ... advisor to the firm, Mr. Traynor will now oversee ... out of the C-Labs office in Redmond, ... , Chief Executive Officer. Photo - ...
Breaking Biology News(10 mins):Inception Technologies to Release New Biometric Reader 2Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 2Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 4C-Labs Names Former Microsoft and Bsquare Executive as Chief Operating Officer 2
... to keep an avian marriage together for the Nazca booby, ... coast of Ecuador. , Many Nazca booby females switch mates ... University study scheduled for publication in the journal Proceedings of ... This is surprising because there is an advantage to staying ...
... research consortium today published a set of papers that ... genome functions. The findings challenge the traditional view of ... genes, pointing instead to a complex network in which ... DNA sequences that do not code for proteins, interact ...
... people die with brains untouched by a pathological process, ... dementia increases with the number of different disease processes ... The research was funded by the National Institute on ... and conducted at the Rush Alzheimer’s Disease Center at ...
Cached Biology News:Study investigates 'divorce' among Galapagos seabirds 2New findings challenge established views on human genome 2New findings challenge established views on human genome 3New findings challenge established views on human genome 4Study finds mix of disease processes at work in brains of most people with dementia 2
(Date:12/24/2014)... 2014   BioLife Solutions , Inc. (NASDAQ: ... of proprietary clinical grade hypothermic storage and ... shipping products for cells and tissues  ("BioLife" or ... 2015 Annual Meeting of Stockholders on May 4, 2015 ... for the Annual Meeting represents a change of more ...
(Date:12/24/2014)... 2014 Earlier this year in a ... director of the Adult Stem Cell Technology Center, LLC ... and under appreciated unique property of adult tissue stem ... Cells: Misunderstood in the Past, Important for the Future,” ... He gave the address at the 4th World ...
(Date:12/24/2014)... According to Ross Selinger, President of Selinger ... the national office market continues to be strong, driven by ... by the third quarter’s surprising 3.9% GDP, unemployment decreasing to ... have held inflation down and the Fed is keeping interest ... remaining soft. , This solid economic news is having a ...
(Date:12/24/2014)... The report expects global cell isolation and expansion market ... a carefully analyzed data about the vital drivers, restraints, ... Full Copy of Report @ http://bit.ly/1yUxy0T , ... expansion will keep witnessing growth at an impressive CAGR ... driven by rapid technological advancements, government funding and investments, ...
Breaking Biology Technology:BioLife Solutions Sets Date for Annual Meeting of Stockholders 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 4ITRA Global Reports Long Island Is Out of Sync With The National Office Market 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 3The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 2The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 3
... ... Cloud-Enabled API for Developers. , ... (Vocus) March 4, 2010 -- This seminar details the fast-growing GenomeQuest sequence data ... will include lunch, discussion, and startup to Free Basic Account., , , , ,When: ...
... ... ... ... ...
... ... aimed at ensuring global food security and sustainability. , ... Washington (PRWEB) -- On March 17, the Global ... and improve storage and distribution to eliminate the global productivity gap, will host a ...
Cached Biology Technology:GenomeQuest Hosting Seminar at ABRF Conference In Sacramento, CA 2OncoGenex Pharmaceuticals to Webcast Discussion of Financial Results for Fourth Quarter and Fiscal Year 2009 2OncoGenex Pharmaceuticals to Webcast Discussion of Financial Results for Fourth Quarter and Fiscal Year 2009 3Gloabl Harvest Initiative: Taking Down Fences To Meet Future Needs 2Gloabl Harvest Initiative: Taking Down Fences To Meet Future Needs 3
... dUTPase The thermostable dUTPase(pyrococcus ... PCR (using proofreading DNA polymerases). ... PCR reactions and dNTP solutions. ... proofreading DNA polymerase reaction can prevent ...
... an exciting product for cell-based kinetic assays ... the use of expensive HTS equipment, which ... the assay development stage. The NOVOstar offers ... as well as any other assay suitable ...
... save space and organize gloves, ... other garb. They are the ... small parts used in labs, ... Open-slot design for easy cleaning. ...
... Agilent Technologies introduces an enhanced ... ICP-MS for Windows 2000 and ... From September 2003, all new ... controlled by the new ChemStation ...
Biology Products: