Navigation Links
Rewind, please: Nature paper shows that cell division is reversible

Gary J. Gorbsky, Ph.D., a scientist with the Oklahoma Medical Research Foundation, has found a way to reverse the process of cell division.

The discovery could have important implications for the treatment of cancer, birth defects and numerous other diseases and disorders. Gorbsky's findings appear in the April 13 issue of the journal Nature.

"No one has gotten the cell cycle to go backwards before now," said Gorbsky, who holds the W.H. and Betty Phelps Chair in Developmental Biology at OMRF. "This shows that certain events in the cell cycle that have long been assumed irreversible may, in fact, be reversible."

Cell division occurs millions of times each day in the human body and is essential to life itself. In the lab, Gorbsky and his OMRF colleagues were able to control the protein responsible for the division process, interrupt and reverse the event, sending duplicate chromosomes back to the center of the original cell, an event once thought impossible.

"Our studies indicate that the factors pointing cells toward division can be turned and even reversed," Gorbsky said. "If we wait too long, however, it doesn't work, so we know that there are multiple regulators in the cell division cycle. Now we will begin to study the triggers that set these events in motion."

The findings may prove important to controlling the development and metastasis of certain cancers. It also holds promise for the prevention and treatment of birth defects and a wide variety of other conditions.

"Dr. Gorbsky's results provide elegant proof that the cell cycle must be precisely controlled," said Dr. Rodger McEver, OMRF vice president of research. "Now he and his lab can work toward developing innovative methods to probe and better understand the complex process of cell division."

Gorbsky heads the Molecular, Cell and Developmental Biology Research Program at OMRF and holds both an M.A. and a Ph.D. in biology from Princeton University.
'"/>

Source:Oklahoma Medical Research Foundation


Page: 1 2

Related biology news :

1. Nature provides inspiration for important new adhesive
2. First production of human monoclonal antibodies in chicken eggs published in Nature Biotechnology
3. Origen publishes in Nature a robust and versatile method for creating transgenic chickens
4. Natures process for nitrogen fixation caught in action
5. UCLA paper examines how one disease may prevent another
6. Recycled paper and compost could both be key tools to control plant disease
7. Developing uses for sugar-cane bagasse: Biotechnology applied to the paper industry
8. McBride shows DNA detective work with paper-eating bacteria that glide
9. Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer
10. “Nano-scissors?laser shows precise surgical capability
11. Clam embryo study shows pollutant mixture adversely affects nerve cell development
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Rewind please Nature paper shows that cell division reversible

(Date:12/11/2014)... , Dec. 09, 2014 Research and ... ( http://www.researchandmarkets.com/research/twhjll/biometrics_market ) has ... in the APAC Region 2015-2019"  report to their ... in this market is advances in technology. With ... upgrade biometric solutions to the latest standard that ...
(Date:12/11/2014)... Dec. 10, 2014  Data Sciences International (DSI), ... released a new series of digital telemetry implants ... researchers. M series, part of the PhysioTel™ Digital ... best possible physiologic data when incorporating functional endpoints ... endpoints to toxicology studies has evolved from short ...
(Date:12/10/2014)... Forest Baptist Medical Center today announced plans for a ... Funding for this $50 million capital project is part ... launched next summer. The medical education ... R.J. Reynolds Tobacco Company complex, adjacent to 525@vine in ... plans to be ready to welcome medical students in ...
Breaking Biology News(10 mins):Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2New telemetry implants expected to change how large animal toxicology studies are conducted 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 4
... A new clinical trial suggests that long-term use ... may significantly reduce the symptoms of genetic heart disease. ... effects of candesartan on left ventricular hypertrophy and function ... in the January issue of The Journal of ...
... Peering at structures only atoms across, researchers have ... nanomotor. Because of the motor,s strength--to scale, ... inspire engineers designing sophisticated nanomachines. In addition, because ... similar motor, including the virus that causes herpes, ...
... 2008) A team of scientists from the New York-based ... coral reefs in areas of Indonesia, following the tsunami that ... today. ... with the Australian Research Council Centre of Excellence for Coral ...
Cached Biology News:Viruses, start your engines! 2Viruses, start your engines! 34 years after tsunami: Corals stage comeback 24 years after tsunami: Corals stage comeback 3
(Date:12/17/2014)... (PRWEB) December 17, 2014 Gene ... that it has entered into a technology access ... (ADM) to apply DNA2.0’s proprietary protein engineering technology, ... process. , “We are extremely excited that the ... platform. This proprietary bioengineering technology has now ...
(Date:12/17/2014)... SOUTH SAN FRANCISCO, Calif. , Dec. 17, ... positive results of a Phase 2 study evaluating ... for the treatment of patients with severe, chronic ... the current standard of care, including topical steroids ... endpoint was percent change in Visual Analog Scale ...
(Date:12/15/2014)...  GlassesOff Inc. (OTCBB: GLSO) announced today the appointment ... director of the Company,s Board of Directors. ... its CEO until its acquisition by Stanley Black ... Recognized as the inventor of the first Wi-Fi-based Active ... -based RFID solutions focused on improving operational efficiency, safety ...
(Date:12/13/2014)... (PRWEB) December 12, 2014 Clarassance, a ... announced its new name: Therabron Therapeutics , Inc. ... and bronchioles (a type of structure in the lungs ... company’s mission to develop novel protein therapeutics for the ... directors decided to change the name to mark the ...
Breaking Biology Technology:ADM and DNA2.0 Enter Into Protein Engineering Technology Access and Service Agreement 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 3Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 4AeroScout Founder Joins GlassesOff's Board of Directors 2AeroScout Founder Joins GlassesOff's Board of Directors 3Maryland-based Biotech Company's Path Forward in Treating Respiratory Diseases Sparks Name Change 2
... Jeff Cunningham and Lynn Jordan , ... Introduction , ... accessory to the Sciclone Advanced Liquid Handler (ALH). This device is designed ... of 96 and 384 well microplates for purposes of liquid transfer (tertiary ...
... Ed Alderman Applied Science and Technology, Caliper Life Sciences, Inc., ... Adams, Jason Brennan Development Integration, Amersham BioSciences, 800 Centennial Avenue, ... Overview , ... the requirement for extended bacterial growth prior to sequencing. The automation ...
... 1 and Bart Moyson 2 , ... a division of Janssen Pharmaceutica N.V., Laboratory of Virology, Beerse, Belgium , ... Sciences Benelux NV, Teralfene, Belgium , ... this paper is to report the performance obtained by dispensing 1μL organic sample ...
Cached Biology Technology:Precision Testing for the Sciclone Advanced Liquid Handler Z8 Option 2Precision Testing for the Sciclone Advanced Liquid Handler Z8 Option 3Precision Testing for the Sciclone Advanced Liquid Handler Z8 Option 4Precision Testing for the Sciclone Advanced Liquid Handler Z8 Option 5Scalable Automation of the TempliPhi DNA Sequencing Template Amplification and DYEnamic ET Terminator Sequencing Kits on the Sciclone ALH 3000 2Scalable Automation of the TempliPhi DNA Sequencing Template Amplification and DYEnamic ET Terminator Sequencing Kits on the Sciclone ALH 3000 3Scalable Automation of the TempliPhi DNA Sequencing Template Amplification and DYEnamic ET Terminator Sequencing Kits on the Sciclone ALH 3000 4Scalable Automation of the TempliPhi DNA Sequencing Template Amplification and DYEnamic ET Terminator Sequencing Kits on the Sciclone ALH 3000 5Scalable Automation of the TempliPhi DNA Sequencing Template Amplification and DYEnamic ET Terminator Sequencing Kits on the Sciclone ALH 3000 696 Well Pipetting Precision Testing Using the Sciclone ALH with a 384 Fixed-Cannula Array 296 Well Pipetting Precision Testing Using the Sciclone ALH with a 384 Fixed-Cannula Array 3
... yellow solution. In PBS ... and other proprietary stabilizers; ... formulated to stabilize activity ... conjugates at high conjugate ...
... is used to predict the ... sequence up to 3,200 bases, ... of primers and GC clamps ... gradient gel electrophoresis (DGGE), constant ...
... Mini-Sub cell GT cell and PowerPac basic power ... of nucleic acids in agarose gels. The Mini-Sub ... with cables and electrodes, a 7 x 7 ... casting gates, and two 1.5 mm fixed-height combs ...
... ReadySub-Cell GT cell and PowerPac basic power supply ... nucleic acids in agarose gels. The mini format ... and electrodes, and leveling bubble. The PowerPac basic ... of 10-300 V, 4-400 mA, and 75 W. ...
Biology Products: