Navigation Links
Revealing the machinery underlying the 'plastic' juvenile brain

at would increase chemical modification of histone. They found that such adult mice, indeed, showed an increase in a form of visual plasticity.

"Our results show that visual experience differently activates intracellular signaling pathways that control gene expression in the visual cortex of juvenile and adult mice, and that this developmental downregulation could regulate the developmental reduction of plasticity occurring in the adult visual cortex," concluded Pizzorusso and colleagues. They also concluded that the closure of the critical period was associated with a decrease in the ability of visual experience to drive the histone modifications that are necessary for neural rewiring.

The researchers concluded that the mechanism they discovered "might be important for plasticity in the visual cortex during the critical period, and its downregulation could be involved in the closure of the critical period."

They wrote that "Thus, multiple molecular mechanisms acting at different levels—extracellularly, on the cell membrane, and intracellularly—might contribute to the developmental downregulation of plasticity occurring in coincidence with the closure of the critical period."


'"/>

Source:Cell Press


Page: 1 2

Related biology news :

1. Scientists take aim at virulent bacteria by decoding machinery of key control enzyme
2. Gambling monkeys give insight into neural machinery of risk
3. Clearing jams in copy machinery
4. New insight into machinery of immune cells tentacles
5. Dissecting the machinery of nicotines reward
6. Biologists probe the machinery of cellular protein factories
7. Change in gene may be underlying molecular defect in some colorectal cancers
8. New mechanism underlying pain found
9. Researchers reverse juvenile diabetes in animal model
10. A puzzle piece found in unraveling the wiring of the brain
11. Mapping neuron connections in the brain
Post Your Comments:
Other Biology Technology:Medco Issues $1.5 Billion of Senior Notes 2Medco Issues $1.5 Billion of Senior Notes 3Nile Therapeutics Reports 2007 Fourth Quarter and Full Year Financial Results 2Nile Therapeutics Reports 2007 Fourth Quarter and Full Year Financial Results 3Angiotech announces filing of audited financial results for the year ended December 31, 2007 and restatement of results for the year ended December 31, 2006 2Angiotech announces filing of audited financial results for the year ended December 31, 2007 and restatement of results for the year ended December 31, 2006 3Angiotech announces filing of audited financial results for the year ended December 31, 2007 and restatement of results for the year ended December 31, 2006 4Angiotech announces filing of audited financial results for the year ended December 31, 2007 and restatement of results for the year ended December 31, 2006 5Angiotech announces filing of audited financial results for the year ended December 31, 2007 and restatement of results for the year ended December 31, 2006 6Angiotech announces filing of audited financial results for the year ended December 31, 2007 and restatement of results for the year ended December 31, 2006 7Angiotech announces filing of audited financial results for the year ended December 31, 2007 and restatement of results for the year ended December 31, 2006 8Angiotech announces filing of audited financial results for the year ended December 31, 2007 and restatement of results for the year ended December 31, 2006 9