Navigation Links
Retroviral resistance gene found

Dr. Stephen Goff and colleagues have identified a novel retroviral resistance gene, called FEZ1, that can mediate a potent resistance to murine leukemia virus, as well as HIV-1, in cell culture. The researchers found that the high level of FEZ1 expression in a specific laboratory rat cell line caused a significant block to retroviral infection ?retroviruses were able to enter the host cells and synthesize the viral DNA, but were excluded from entering the host cell nucleus.

"We suspect that the overexpression of FEZ1 interferes with intracellular trafficking of the viral preintegration complex and traps the viral DNA in the cytoplasm. We hope that learning more about this transport machinery might reveal a new target for antiviral drugs in the treatment of HIV-1 disease."


'"/>

Source:Cold Spring Harbor Laboratory


Page: 1

Related biology news :

1. Study identifies predictors of HIV drug resistance in patients beginning triple therapy
2. Researchers make gains in understanding antibiotic resistance
3. MUHC scientists describe genetic resistance to rampant virus
4. New polysaccharide may help combat multidrug resistance in cancer
5. New book explains antibiotic resistance for a broad audience
6. Insects develop resistance to engineered crops
7. Drug resistance testing in treatment-naive HIV patients is cost-effective
8. Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance
9. Gaining ground in the race against antibiotic resistance
10. Genes linked to treatment resistance in children with leukemia
11. Einstein researchers identify new way that bacteria develop resistance to antibiotics
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/17/2016)... Global Market Watch: Primarily supported by ownership types; ... Academics) market is to witness a value of US$37.1 billion ... Compounded Annual Growth Rate (CAGR) of 10.75% is foreseen from ... 2014-2020. North America is not way ... Europe at 9.56% respectively. Report Focus: ...
(Date:11/14/2016)... Technology, Inc. ("xG" or the "Company") (Nasdaq: XGTI, XGTIW), ... in challenging operating environments, announced its results for the ... a conference call to discuss these results on November ... Key Recent Accomplishments ... acquire Vislink Communication Systems. The purchase is expected to ...
(Date:6/22/2016)... June 22, 2016 On Monday, the Department ... industry to share solutions for the Biometric Exit Program. ... and Border Protection (CBP), explains that CBP intends to ... the United States , in order ... defeat imposters. Logo - http://photos.prnewswire.com/prnh/20160622/382209LOGO ...
Breaking Biology News(10 mins):
(Date:12/6/2016)... ... December 06, 2016 , ... Discovering new clues to natural ... with lasers what’s happening in our brains. And searching for keys to our immune ... research being honored with the 2017 Edith and Peter O’Donnell Awards by ...
(Date:12/6/2016)... According to a new market research report "Microfluidics Market ... (Genomics, Proteomics, Capillary Electrophoresis, POC, Clinical, Environmental, Drug Delivery) - Global ... to reach USD 8.78 Billion by 2021 from USD 3.65 Billion ... (2016 to 2021). Continue Reading ... ...
(Date:12/6/2016)...  The Texas Medical Center (TMC) and ... today announced the establishment of a new international BioBridge, ... Australia and the Texas Medical Center, the ... HISA and the Texas Medical Center, with the support ... global health innovation ecosystem where emerging technologies can be ...
(Date:12/5/2016)... ... December 05, 2016 , ... ... cellulose nanocrystals and cellulose nanofibrils. The composition claims are not limited to ... claims directed to combination with polymers, carbon fibers, graphene, and other materials. ...
Breaking Biology Technology: