Navigation Links
Results with newer bladeless LASIK equivalent to standard microkeratome LASIK

A Mayo Clinic study comparing femtosecond (bladeless) and mechanical microkeratome LASIK surgeries has found equal results from both types six months post-surgery, using a variety of vision and eye health measurements. The study's findings will be presented next week in three abstracts at the Association for Research in Vision and Ophthalmology meeting in Fort Lauderdale, Fla.

LASIK (Laser-assisted in situ keratomileusis) involves treating nearsightedness, farsightedness or astigmatism by reshaping the eye's cornea to alter the way the eye refracts light. LASIK involves creating a flap, removing a defined amount of corneal tissue by an excimer laser, and replacing the flap. In standard LASIK with a mechanical microkeratome, the flap is created by a blade; in bladeless LASIK, the newer type, the flap is created by a femtosecond laser.

"At six months after surgery, there are no differences between the eyes that had bladeless or microkeratome LASIK with respect to visual acuity (vision as measured by reading an eye chart), contrast sensitivity (ability to discriminate bright objects from dark objects), or in perception of stray light or glare, such as the glare from oncoming headlights," says Sanjay Patel, M.D., Mayo Clinic ophthalmologist and study investigator.

Given the equivalent findings thus far in eye health and vision between the two types of LASIK, Dr. Patel slightly prefers bladeless LASIK due to its potential safety, which was not measured in his study. "I'd say the short-term outcomes are equal and the risks are, in theory, less with the bladeless technique, although our study was not designed to compare risks," he says. "Bladeless LASIK is potentially safer because of its computer-controlled precision, the ability to visualize the flap being created, and to stop the procedure whenever necessary. That said, however, the risk of complications with a traditional, microkeratome blade is very small: some vision loss from surgery with a microkeratome blade occurs in well under 1 percent of all cases. The long-term risks of either procedure, however, are unknown, and defining them is the primary purpose of our study."

The study followed 20 patients who received LASIK for nearsightedness or astigmatism. Each patient was treated with microkeratome LASIK in one eye and bladeless LASIK in the other eye. The researchers found no difference in subbasal nerve density between types of surgery, though the density decreased after both treatments compared to density before LASIK. Corneal sensitivity did not differ between microkeratome and bladeless LASIK. Subbasal nerve density and corneal sensitivity do not impact vision, but rather the potential to heal from a scratch or other injury to the eye. High-contrast visual acuity, the capability to see fine details, and contrast sensitivity, the ability to perceive contrast in objects and their environments, also did not differ between LASIK types. The researchers found corneal backscatter was greater with bladeless LASIK for the first three months after surgery, yet the patients perceived no difference in vision after three months between their eyes treated with bladeless or microkeratome LASIK. Backscatter is haziness in the cornea that is usually invisible to the naked eye and is identified through testing in a physician's office. Cell densities in all layers of the cornea also did not differ between the LASIK surgeries.

The ultimate goal of the Mayo Clinic study of microkeratome versus bladeless LASIK is to obtain long-term information about patients' vision and eye health five years following surgery. The results presented now represent the first six months of findings.


Source:Mayo Clinic

Related biology news :

1. Results of worlds first gene therapy trial for arthritis show approach safe, feasible
2. Combating anthrax: Results of study published this month as researchers look for a better vaccine
3. Expression Project for Oncology (expO) completes first phase of standardized gene expression analyses
4. Carnegie Mellon U. transforms DNA microarrays with standard Internet communications tool
5. Setting the standard for computer models of life
6. DOE JGI sets gold standard for metagenomic data analysis
Post Your Comments:

(Date:11/19/2015)... , Nov. 19, 2015  Although some 350 ... is dominated by a few companies, according to Kalorama ... own 51% of the market share of the 6.1 ... The World Market for Molecular Diagnostic s . ... "The market is still controlled by one company and ...
(Date:11/17/2015)... 2015  Vigilant Solutions announces today that Mr. ... Directors. --> --> ... the partnership at TPG Capital, one of the largest ... Billion in revenue.  He founded and led TPG,s Operating ... companies, from 1997 to 2013.  In his first role, ...
(Date:11/12/2015)...   Growing need for low-cost, easy to ... paving the way for use of biochemical sensors ... in clinical, agricultural, environmental, food and defense applications. ... medical applications, however, their adoption is increasing in ... emphasis on improving product quality and growing need ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... -- Cepheid (NASDAQ: CPHD ) today announced that ... and invited investors to participate via webcast. ... 1, 2015 at 11.00 a.m. Eastern Time --> ... 1, 2015 at 11.00 a.m. Eastern Time --> ... NY      Tuesday, December 1, 2015 at 11.00 ...
(Date:11/24/2015)... /PRNewswire/ - Aeterna Zentaris Inc. (NASDAQ:  AEZS) (TSX: AEZ) (the ... the Toronto Stock Exchange, confirms that as of the ... developments that would cause the recent movements in the ... --> About Aeterna Zentaris Inc. ... Aeterna Zentaris is a specialty biopharmaceutical company engaged in ...
(Date:11/24/2015)... 24, 2015 SHPG ) announced today that ... Piper Jaffray 27 th Annual Healthcare Conference in ... at 8:30 a.m. EST (1:30 p.m. GMT). --> SHPG ... will participate in the Piper Jaffray 27 th Annual Healthcare ... Tuesday, December 1, 2015, at 8:30 a.m. EST (1:30 p.m. GMT). ...
(Date:11/24/2015)... ... November 24, 2015 , ... In harsh industrial ... points for in-line sensors can represent a weak spot where leaking process media ... of retractable sensor housings , which are designed to tolerate extreme process conditions. ...
Breaking Biology Technology: