Navigation Links
Resistant HIV quickly hides in infants' cells

New evidence shows that drug-resistant virus passed from mother-to-child can quickly establish itself in infants?CD4+ T cells where it can hide for years, likely limiting their options for future treatment. The study is published in the May 15 issue of The Journal of Infectious Diseases, now available online.

Mother-to-child transmission of HIV is an important factor in the AIDS pandemic, although important strides have been made in limiting transmission with antiviral drug therapies before, during, and following birth. In the last few decades the rate of mother-to-child transmission of HIV in the United States has been reduced from 25 percent to its current rate of less than 2 percent. However, the transmission of drug-resistant strains of HIV from mother to child is still a problem, and much is unknown concerning how such transmission affects the responses of infants to various drug treatments.

The study, conducted by Deborah Persaud, MD, of Johns Hopkins University School of Medicine and colleagues working throughout the United States, analyzed HIV-infected infants less than six months of age enrolled in a large, multi-center clinical trial covering 10 states.

Their results showed that five of 21 HIV-positive infants were infected with drug-resistant HIV transmitted from their mothers—a surprisingly high figure. Of those five, four were resistant to non-nucleoside reverse transcriptase inhibitors (NNRTIs), a common class of antiretroviral drug used to treat HIV infection and to prevent mother-to-child transmission. All had uncommon drug-resistance mutations that some resistance tests would miss.

Earlier studies looking at infants treated with antiretrovirals in an unsuccessful attempt to prevent mother-to-child transmission found the virus quickly developed resistance, but levels of resistant virus declined over time to undetectable levels. In the current study, however, researchers found these resistant viruses quickly
'"/>

Source:Infectious Diseases Society of America


Page: 1 2 3

Related biology news :

1. Antibiotic Resistant Bacterium Uses Sonar-like Strategy to “See?Enemies or Prey
2. Resistant bacteria increasing source of muscle infection
3. To translate touch, the brain can quickly rearrange its sense of the body
4. Gene patterns in white blood cells quickly diagnose disease
5. Animals can change genes quickly to keep up with viral ingenuity
6. New MRI technique quickly builds 3-D images of knees
7. Mussels evolve quickly to defend against invasive crabs
8. Biodegradable napkin -- featuring sensitive nanofibers -- may quickly detect biohazards
9. Drug can quickly mobilize an army of cells to repair injury
10. A new portable biosensor detects traces of contaminants in food more quickly and cheaply
11. Asexual worm quickly adapts to soil contamination
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Resistant HIV quickly hides infants cells

(Date:8/22/2014)... In 2015, American consumers will finally be able to ... Although touted as zero-emissions vehicles, most of the cars ... fossil fuel that contributes to global warming. , Now ... device that uses an ordinary AAA battery to produce ... electric current through two electrodes that split liquid water ...
(Date:8/21/2014)... A new study of American singles found that ... the highest orgasm rates. On average, men experience ... sexual orientation making little difference. For women, however, ... experience orgasm 62.9 percent of the time during ... pattern varies with women,s sexual orientation, with lesbian ...
(Date:8/21/2014)... skin fungus linked to dandruff, eczema and other itchy, ... even further global reachesincluding Hawaiian coral reefs and the ... , A review in the scientific journal PLOS ... the fungi of the genus Malassezia in ... datasets from around the world. , University of Hawai,i ...
Breaking Biology News(10 mins):Stanford scientists develop a water splitter that runs on an ordinary AAA battery 2Stanford scientists develop a water splitter that runs on an ordinary AAA battery 3Orgasm rates for single women less predictable than men's, vary by sexual orientation 2Orgasm rates for single women less predictable than men's, vary by sexual orientation 3Orgasm rates for single women less predictable than men's, vary by sexual orientation 4From dandruff to deep sea vents, an ecologically hyper-diverse fungus 2
... entities conducting research in synthetic biology worldwide grew significantly ... of an interactive map produced by the Synthetic Biology ... The map is available online at http://www.synbioproject.org/map . ... the design and construction of new biological parts and ...
... Centers for Disease Control, about one in six Americans gets ... of raw oysters in the U.S. are estimated to cost ... of health risk from eating raw oysters, Texas A&M University ... scientist Dr. Suresh Pillai and a team of researchers from ...
... 2013 Signal Hill, CA Bowman Design Group, an ... exhibits, and event marketing, is the first and only ... certification from FAMAB, the German exhibition and events industry ... established that the company met or exceeded goals set ...
Cached Biology News:Synthetic biology research community grows significantly 2Electron-beam pasteurization of raw oysters may reduce viral food poisoning 2Electron-beam pasteurization of raw oysters may reduce viral food poisoning 3Bowman Design Group is first US company awarded German FAMAB 'Sustainable Company' certification 2
(Date:8/22/2014)... 22, 2014 Research and Markets ... Biology Enzymes, Kits, & Reagents (Cloning, Epigenetics, PCR, Restriction ... to their offering. The global molecular ... 2013, and is expected to grow at a CAGR ... biology enzymes, kits, & reagents find applications in a ...
(Date:8/21/2014)... , Aug. 21, 2014  BioSpecifics Technologies ... company developing first in class collagenase-based products marketed ... CCH) in the U.S. and XIAPEX ® ... results from a randomized, double-blind Phase 2a study ... or edematous fibrosclerotic panniculopathy. The results showed that ...
(Date:8/21/2014)... , August 21, 2014 ... http://www.researchandmarkets.com/research/3zh3q8/global_hormone ) has announced the addition of ...  report to their offering.       ... as hormone therapy, is a means of ... produced by the body. This type of ...
(Date:8/21/2014)... , Aug. 21, 2014 Mathematic studies at the ... University , and funded by the Jeffrey Epstein VI ... tumors can be visually identified for elimination. These aggressive cells ... study, which shows a topological map of what to look ... cancer research, for while tumor cells can be extracted from ...
Breaking Biology Technology:Global Molecular Biology Enzymes, Kits, & Reagents (Cloning, Epigenetics, PCR, Restriction Digestion, Sequencing) Market - Forecast to 2018 2Global Molecular Biology Enzymes, Kits, & Reagents (Cloning, Epigenetics, PCR, Restriction Digestion, Sequencing) Market - Forecast to 2018 3BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 2BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 3BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 4BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 5Global Hormone Replacement Therapy Market 2014-2018: Key Vendors are Actavis, Bayer, Merck & Co, Novartis and Novo Nordisk 2Science Power Jeffrey Epstein and Harvard University Fund Project to Visually Stop Tumor Growth 2
... GeoPharma, Inc. (Nasdaq:,GORX) (the "Company") announced today in an ... audience as possible it has placed both of the ... at, http://www.GeoPharmainc.com under the "Analyst Coverage" tab in ... publicly several times in,the next few months., In ...
... Rigel,Pharmaceuticals, Inc. (Nasdaq: RIGL ) today announced that ... is scheduled to present,a company overview at the BIO ... February 11 at 11:45 a.m. EST., To access ... on to http://www.rigel.com . Please connect to Rigel,s ...
... Feb. 6 Cell Therapeutics, Inc. (CTI),(Nasdaq: CTIC ; MTAX) management will ... at 1:15 PM in the West Foyer,of the Waldorf-Astoria Hotel., The presentation ... The webcast can be accessed at, http://www.cticseattle.com ., , ... BIO CEO & Investor Conference ...
Cached Biology Technology:Recent Research Reports and Near-Term Corporate Events 2Recent Research Reports and Near-Term Corporate Events 3
... Time- and temperature-controlled microwave oven ... and Antigen Retrieval of formalin-fixed, ... ease of use, high throughput ... high performance. When used in ...
... reagents and supplies, for 10 chips, ... to perform protein analysis with 10 ... system. Supplied are 3 x 520 ... stain, 60 microliters Pro260 ladder (10-260 ...
...
... submicron range are part of your production ... of particle size is important to you. ... detect the component populations in your sample ... Analyzer uses Photon Correlation Spectroscopy (PCS) , ...
Biology Products: