Navigation Links
Researchers shed light on shrinking of chromosomes

A human cell contains an enormous 1.8 metres of DNA partitioned into 46 chromosomes. These have to be copied and distributed equally into two daughter cells at every division. Condensation, the shortening of chromosomes, allows the cell to handle such huge amounts of genetic material during cell division and helps preventing fatal defects in chromosome separation. Now researchers from the European Molecular Biology Laboratory (EMBL) for the first time tracked chromosome condensation in mammalian cells over the entire course of cell division. In this week’s advanced online publication of Nature Cell Biology they report crucial new insights into timing, function and molecular basis of chromosome condensation.

What happens when chromosomes are not correctly separated and distributed during cell division we know very well; two daughter cells with either broken chromosomes or different numbers of chromosomes result and severe diseases including cancer can arise. But so far we know only little about condensation, a process crucial to the successful separation of chromosomes. Using powerful microscopes, researchers led by Jan Ellenberg at EMBL looked at living mammalian cells to find out how and when chromosomes shorten during cell division.

Condensation begins early, when the cell starts preparing for division, and the chromosomes become shorter and shorter until they are about to separate and migrate towards the poles of the cell.

“It is at this stage that textbooks say chromosomes are shortest. Then, after separating they would expand again,” says Ellenberg. “But we found something very different. Shortly after they finish separating, chromosomes actually condense even further. This makes sense, because in this way they are shortest when the physical division of one cell body into two takes place. Like this, no long chromosome arms extend over the plane of division, because that could expose the DNA to serious mechanical damage.”

Th
'"/>

Source:European Molecular Biology Laboratory


Page: 1 2

Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. Researchers reveal the infectious impact of salmon farms on wild salmon
5. Researchers identify target for cancer drugs
6. Researchers discover molecule that causes secondary stroke
7. Researchers find missing genes of ancient organism
8. Researchers trace evolution to relatively simple genetic changes
9. Researchers add new tool to tumor-treatment arsenal
10. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
11. VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Researchers shed light shrinking chromosomes

(Date:8/20/2014)... therapy developed by researchers at the University of Missouri ... from a life-threatening heart condition caused by muscular dystrophy. ... Yi Lai, Ph.D., the leading author of the study ... Medicine,s Department of Molecular Microbiology and Immunology. "This is ... lead to a treatment for people with this devastating ...
(Date:8/20/2014)... 1 (PS1) absorbs light and its energy is ... to biomass. Photovoltaic devices, mostly build from silicon ... electricity. One approach for the development of cheaper ... with the isolated membrane protein complexes of photosynthesis. ... stable PS1 from thermophilic cyanobacteria that live in ...
(Date:8/19/2014)... to decrease China,s increasing caesarean section rate, suggests a ... An International Journal of Obstetrics and Gynaecology (BJOG) . ... rates in the world. Of 16 million babies born ... exact rate is not known, the current Chinese language ... rates ranging from 36% to 58%. However, before the ...
Breaking Biology News(10 mins):Gene therapy protects mice from lethal heart condition, MU researchers find 2A semi-artificial leaf faster than 'natural' photosynthesis 2Is China's 50 percent cesarean section delivery rate too high? 2Is China's 50 percent cesarean section delivery rate too high? 3
... urine test for prostate cancer that measures minute fragments ... through the University of Michigan MLabs. The new testMi-Prostate ... increases physicians, ability to pick out high-risk prostate tumors ... of thousands of men avoid unnecessary biopsies. The ...
... 2013 MedNet Solutions , a global life ... is pleased to announce that Accelovance , an ... phase Oncology, Vaccines and General Medicine development, has joined ... .    Designation as an iMedNet Partner will ...
... the first ever interior 3D map of Italy,s iconic Leaning ... system. Developed by the CSIRO, Australia,s national science agency, ... a laser scanner that sways on a spring to capture ... an operator can walk through it. Specialised software then converts ...
Cached Biology News:Prostate Cancer Foundation announces new urine test for prostate cancer available 2Prostate Cancer Foundation announces new urine test for prostate cancer available 3MedNet Solutions Proudly Welcomes Accelovance To The iMedNet Partner Program 2MedNet Solutions Proudly Welcomes Accelovance To The iMedNet Partner Program 33D mapping is a 'Pisa' cake for Aussie scientists 2
(Date:8/21/2014)... (PRWEB) August 21, 2014 Ontotext ... today by Ontotext . Now the same ... analysis of structured and unstructured data is available to ... cost of enterprise technology. Organizations that do not have ... data management can use S4 since there is no ...
(Date:8/21/2014)... On Wednesday of last week RENU 28, the world's ... became available for purchase in Australia and New Zealand, and ... 28 works is, if you think about the definition of ... cellular renewal within your body. If you think about the ... cellular renewal. What RENU 28 does is it works with ...
(Date:8/20/2014)... lessons often have it that American Indians largely were ... pox, influenza and tuberculosis brought to the New World ... about 20 million people lived in the Americas shortly ... were killed by European diseases., But new research led ... and Johannes Krause of the University of Tubingen in ...
(Date:8/20/2014)... (PRWEB) August 20, 2014 High ... and apply the most complete climate and Earth ... demanding climate change issues. , Eight national laboratories, ... with the National Center for Atmospheric Research, four ... new effort. Other participating national laboratories include Argonne, ...
Breaking Biology Technology:Ontotext Releases Text Mining & Semantic Technology Running in the Cloud – Welcome to “S4? 2Ontotext Releases Text Mining & Semantic Technology Running in the Cloud – Welcome to “S4? 3Ontotext Releases Text Mining & Semantic Technology Running in the Cloud – Welcome to “S4? 4RENU 28 Skin Care Now Available in Australia and New Zealand 2Unusual discovery leads to fascinating tuberculosis theory 2Unusual discovery leads to fascinating tuberculosis theory 3New Project Is the ACME of Addressing Climate Change 2New Project Is the ACME of Addressing Climate Change 3
... be allowed to tax Internet usage, in a move that ... hole in the state budget. , ,The federal measure to ... , R-Wis., who said home users could save around a ... Tax Nondiscrimination Act, a tech-neutral plan that exempts all Internet ...
... Dark Ages, where marks were burned onto cattle. On ever-so-slowly-evolving minds ... solid impression and provides a daily dose of comfort. Belonging to ... a security blanket. A warm fuzzy feeling when a huge name ... craves to carry something with a logo, color and stripes, wear ...
... Wis. The North Carolina simulated learning company ... the Croquet Project at UW-Madison, a graphical communications ... trade show in Orlando that it has begun developing software ... applied to military and commercial avenues. , ,What were doing ...
Cached Biology Technology:State faces revenue drop as federal Internet tax ban passes House 2The black hole of corporate branding 2The black hole of corporate branding 3The black hole of corporate branding 4UW open-source 3D environment tapped for commercial development 2
... software, PC, is used to perform ... obtained from the Experion automated electrophoresis ... electropherogram and simulated gel views and ... in a Results table. This software ...
... use in the Microsart e.motion are sterile-sealed, without ... a specially designed individual package on a band. ... of membrane filter units ensures that they are ... sealed band guarantees uniform dispensing of the individual ...
... that will help protect your PCR runs ... work area prior to use, reducing the ... Containment features reduce the chance of airborne ... for a clear view, an acid-resistant black ...
...
Biology Products: