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Researchers reverse juvenile diabetes in animal model

1 diabetes. According to the NIH, 5 percent to 10 percent of diagnosed diabetes cases in the United States are type 1 diabetes.

Type 1 diabetes is regarded as an autoimmune disease because a person's immune system attacks and destroys the beta cells in the pancreas that produce insulin. Symptoms of type 1 diabetes usually develop over a short period of time and include increased thirst, frequent urination, constant hunger, weight loss, blurred vision and extreme fatigue. People with type 1 diabetes require numerous daily injections of insulin to survive.

About Dr. Trucco

Massimo Trucco, MD, has dedicated his life's work to finding a cure for diabetes -- finding a cure is a personal quest for him. As an international leader in the field of immunogenetics, Dr. Trucco has pioneered numerous important studies and also maintains a federally funded national bone marrow HLA typing center within his lab.With this funding, Dr. Trucco and his team are able to continue their landmark research into improving the prediction of type 1 diabetes and understanding and managing its complications. Building on his discovery in 1994 that type 1 diabetes susceptibility may be genetic in nature and triggered by viruses, Dr. Trucco's discoveries have continue to lead to better processes for molecular typing for matching bone marrow donors and recipients, the ability to identify those at risk for diabetes, an understanding of the link between a common virus and type 1 diabetes, and a potential cure for the pancreatic damage that causes insulin dependence.

Diabetes and children statistics:

  • The risk of developing type 1 diabetes is higher than virtually all other severe chronic diseases of childhood.
  • Peak incidence occurs during puberty, around 10 to 12 years of age in girls, and around 12 to 14 years of age in boys.
  • The symptoms of type 1 diabetes can resemble the flu in children.
  • Type 1 diabetes tends to run in families. Brothers
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Source:Children's Hospital of Pittsburgh


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